ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) Kits ELISA

The membrane-associated protein encoded by ABCB11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ABCB11 Anticorps (65) et ABCB11 Protéines (8) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
ABCB11 8647 O95342
ABCB11 27413 Q9QY30
ABCB11 83569 O70127
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Top ABCB11 Kits ELISA sur anticorps-enligne.fr

Showing 3 out of 14 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 15 to 18 Days
$910.56
Détails
Souris 4.7 pg/mL 18.75-1200 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 15 to 18 Days
$910.56
Détails
Rat < 33 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$653.82
Détails

Plus Kits ELISA pour ABCB11 partenaires d'interaction

Rainbow Trout (Oncorhynchus mykiss) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) interaction partners

  1. Data show the gene expression profiling of ABC (Montrer ABCB6 Kits ELISA) transporters in seven tissues.

  2. cloned one partial and two full gene sequences, which show high degree of identity with mammalian Pgp1 (ABCB1 (Montrer ABCB1 Kits ELISA)), BSEP (ABCB11) and MRP2 (ABCC2 (Montrer ABCC2 Kits ELISA)) efflux transporters and found identical relative expression patterns for both liver and primary hepatocytes

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) interaction partners

  1. We concluded that Egyptian patients having chronic hepatitis C genotype 4 with CC genotype of ABCB11 SNP 1331T>C and high plasma bile acid levels at cutoff value of 75.5 mumol/L were associated with advanced hepatic fibrosis.

  2. The overrepresentation of mutated variants of the 1331T > C ABCB11 polymorphism in the ICP group suggests its contribution to the etiology of the intrahepatic cholestasis of pregnancy. Analysis of genotypes' co-existence pointed to the possibility of the mutated variants of polymorphism 1954A > G ABCB4 (Montrer ABCB4 Kits ELISA) and 1331T > C ABCB11 having a summation effect on the development ofintrahepatic cholestasis of pregnancy

  3. These data demonstrated that c.386G>A (p.C129Y) in ABCB11 was a causative mutation that correlated with the phenotype of patients with PFIC2, the impairment of biliary excretion into bile canaliculi, and the absence of canalicular BSEP expression in liver histological assessments.

  4. FIC1, BSEP, and MDR3 (Montrer ABCB4 Kits ELISA) represent hepatobiliary transport proteins essential for bile formation.

  5. This is the first report on a diagnostic test for simultaneous genotyping of IFNL3, ABCB11, and RNF7 in Chronic hepatitis C (CHC) patients. Reliable and inexpensive, the assay should provide useful information for the clinical management of CHC, like identification of patients at risk of rapid disease progression or with high chances of response to classic therapy.

  6. Residual function of BSEP as well as substrate specificity influence the therapeutic effectiveness of partial external biliary diversion in progressive familial intrahepatic cholestasis type 2.

  7. Study suggested that the CC genotype of rs2287616 variant of ABCB11 gene might contribute to anti-tuberculosis drug-induced cholestatic liver injury in Chinese patients.

  8. Case Report: compound heterozygotes for two missense mutations of the ABCB11 with a mild form of progressive familial intrahepatic cholestasis type 2.

  9. Patients with a confirmed ABCB11 or tight junction protein 2 gene mutation (n = 7) had a minimally detectable THBA proportion (0.23-2.99% of total BAs). Three patients with an ATP8B1 mutation had an elevated THBA proportion (7.51-37.26%).

  10. By these complementary approaches, a set of ten novel BSEP interaction partners was identified. With the exception of radixin (Montrer RDX Kits ELISA), all other interaction partners were integral or membrane-associated proteins including proteins of the early secretory pathway and the bile acyl-CoA synthetase (Montrer SLC27A5 Kits ELISA), the second to last, ER-associated enzyme of bile salt synthesis

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) interaction partners

  1. Studied effect of endotoxin exposure on liver following partial hepatectomy; found endotoxin exposure induced autoantibody production against Bsep (bile salt export pump) leading to dysfunction of hepatobiliary transporter systems.

  2. Isoniazid/rifampicin administration significantly down-regulated the expression of hepatic bile acids transporters Ntcp (Montrer SLC10A1 Kits ELISA) and Bsep in liver.

  3. mechanism of increased biliary lipid secretion in Bsep-/- mice is based on increased expression of the responsible canalicular transporter proteins.

  4. LKB1 (Montrer STK11 Kits ELISA)/AMPK (Montrer PRKAA1 Kits ELISA) and PKA control ABCB11 trafficking and polarization in hepatocytes.

  5. CA feeding of Bsep (-/-) mice increased hepatic Cyp3a11 protein levels.

  6. FXR (Montrer NR1H4 Kits ELISA) regulates BSEP in an isoform-dependent and species-specific manner

  7. Ursodeoxycholic acid fed to abcb11-/- mice caused liver damage and the appearance of biliary tetra- and penta-hydroxy bile acids.

  8. Hepatic Abcb11 overexpression in mice increases the conservation of bile acids within the enterohepatic circulation.

  9. The authors show that two of these transporters, ABCB11 and ATP8B1, are functional targets of miR (Montrer MLXIP Kits ELISA)-33, a micro-RNA that is expressed from within an intron of SREBP-2 (Montrer SREBF2 Kits ELISA).

  10. Abcb11 deficiency induces cholestasis coupled to impaired beta-fatty acid oxidation in mice.

ABCB11 profil antigène

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

Gene names and symbols associated with ABCB11

  • ATP binding cassette subfamily B member 11 (ABCB11) anticorps
  • bile salt export pump (LOC100489744) anticorps
  • bile salt export pump (LOC100565276) anticorps
  • bile salt export pump (EDI_111220) anticorps
  • bile salt export pump (EDI_272930) anticorps
  • bile salt export pump (abcb11) anticorps
  • ATP binding cassette subfamily B member 11 (Abcb11) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 11 (Abcb11) anticorps
  • ABC16 anticorps
  • ABCB11 anticorps
  • BRIC2 anticorps
  • BSEP anticorps
  • BSEP/SPGP anticorps
  • Lith1 anticorps
  • PFIC-2 anticorps
  • PFIC2 anticorps
  • PGY4 anticorps
  • Spgp anticorps

Protein level used designations for ABCB11

ATP-binding cassette, sub-family B (MDR/TAP), member 11 , bile salt export pump , bile salt export pump-like , ABC member 16, MDR/TAP subfamily , ATP-binding cassette sub-family B member 11 , progressive familial intrahepatic cholestasis 2 , sister p-glycoprotein , ATP-binding cassette, sub-family B, member 11 , sister of P-glycoprotein , liver bile salt export pump

GENE ID SPECIES
424170 Gallus gallus
470717 Pan troglodytes
488390 Canis lupus familiaris
531150 Bos taurus
100024107 Monodelphis domestica
100052359 Equus caballus
100083318 Ornithorhynchus anatinus
100404882 Callithrix jacchus
100454135 Pongo abelii
100473353 Ailuropoda melanoleuca
100489744 Xenopus (Silurana) tropicalis
100518154 Sus scrofa
100543935 Meleagris gallopavo
100565276 Anolis carolinensis
100590891 Nomascus leucogenys
5879080 Entamoeba dispar SAW760
5914265 Entamoeba dispar SAW760
100136688 Oncorhynchus mykiss
100337637 Cavia porcellus
8647 Homo sapiens
27413 Mus musculus
100008767 Oryctolagus cuniculus
83569 Rattus norvegicus
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