ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) Kits ELISA

The protein encoded by ABCC10 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 Anticorps (96) et ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
ABCC10 89845 Q5T3U5
Anti-Souris ABCC10 ABCC10 224814 Q8R4P9
Anti-Rat ABCC10 ABCC10 316231  
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Top ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 Kits ELISA sur anticorps-enligne.fr

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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.061 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$810.53
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Plus Kits ELISA pour ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 partenaires d'interaction

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) interaction partners

  1. In the cancer cell lines, only rs2125739 of ABCC10 gene was significantly associated with docetaxel cytotoxicity, and this was confirmed in the genome-edited cell line. In the non-small cell lung cancer (NSCLC) patients, there were no significant differences related to rs2125739 genotype in terms of response rate, progression free and overall survival. However, this SNP was associated with grade 3/4 neutropenia.

  2. FOXM1 promotes 5-FU resistance by up-regulating ABCC10 expression in colorectal tumor cells.

  3. It is thus inferred, that ABCC10 expression in CWR22Rv1 cells is not S phase-specific but is primarily associated with cell proliferation.

  4. The present study shows that the protein expression of ABCC10 significantly associates with overall survival and the expression of ABCC11 with disease-free interval of colorectal cancer patients

  5. BAG3-mediated miRNA let-7g and let-7i inhibit proliferation and enhance apoptosis of human esophageal carcinoma cells by targeting the drug transporter ABCC10 and modulates cisplatin resistance.

  6. the combination of paclitaxel and masitinib could serve as a novel and useful therapeutic strategy to reverse paclitaxel resistance mediated by ABCC10

  7. ABCC10 expression is correlated with human breast cancer subtype using breast tissue microarrays.

  8. This report describes the ATPase activity of ABCC10 and further revealed ABCC10 localizes basolaterally using an in vitro system. The described work also identifies the tyrosine kinase sorafenib as an inhibitor of ABCC10.

  9. Study establishes that ABCC10 is able to modulate taxane resistance in vivo using a mouse model.

  10. Study establishes that ABCC10 confers resistance to several classes of agents including nucleoside analogs (cytabarine, dideoxycytidine) and epothilone B.

  11. This study shows that ABCC10 confers resistance to the anticancer agents taxanes and vinca alkaloids in vitro.

  12. MRP7 has the facility for mediating the transport of conjugates such as E(2)17betaG indicates that it is a lipophilic anion transporter involved in phase III (cellular extrusion) of detoxification.

  13. First study to describe structure and expression pattern of this transporter.

  14. Tetrandrine and 5-bromotetrandrine can both reverse multidrug resistance in K562 cells by reducing expression of MRP7.

  15. Multivariate regression analysis identified carriage of a composite genotype of ABCC10 rs2125739 to be associated with nevirapine plasma concentrations

  16. Tenofovir is a substrate for ABCC10, and genetic variability within the ABCC10 gene may influence tenofovir renal tubular transport and contribute to the development of kidney tubular dysfunction.

  17. Imatinib and nilotinib reverse multidrug resistance in cancer cells by inhibiting the efflux activity of the MRP7 (ABCC10)

  18. The genomic organization and gene expression regulation of human multidrug resistance-associated protein 7 and a splicing variant MRP7A were identified

  19. A non-major histocompatibility complex MRP7 leader peptide ALALVRMLI binds to HLA-E and strongly inhibits natural killer (NK) cell-mediated lysis

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) interaction partners

  1. Abcc10 is dispensable for health and viability and it is an endogenous resistance factor for taxanes, other natural product agents, and nucleoside analogues

  2. MDR1 expression, MRP1 expression, and MRP7 expression are refractory factors in head and neck cancer chemotherapy; induction of MRP7 expression is involved in drug resistance to natural products, especially to docetaxel in salivary gland adenocarcinoma

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) profil antigène

Antigen Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ABCC10

  • ATP binding cassette subfamily C member 10 (ABCC10) anticorps
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 10 (Abcc10) anticorps
  • ATP binding cassette subfamily C member 10 (Abcc10) anticorps
  • EST182763 anticorps
  • mFLJ00002 anticorps
  • Mrp7 anticorps
  • SIMRP7 anticorps

Protein level used designations for ABCC10

ATP-binding cassette sub-family C member 10 , multidrug resistance-associated protein 7 , ATP-binding cassette, sub-family C (CFTR/MRP), member 10 , ATP-binding cassette, subfamily C (CFTR/MRP), member 10

GENE ID SPECIES
89845 Homo sapiens
224814 Mus musculus
316231 Rattus norvegicus
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