anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4) Anticorps

The protein encoded by ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ATP-Binding Cassette, Sub-Family D (Ald), Member 4 Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ABCD4 5826 O14678
ABCD4 299196  
ABCD4 19300 O89016
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Top anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 4 Anticorps sur anticorps-enligne.fr

Showing 10 out of 63 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-ABCD4 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  721_B cell lysate ABCD4 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Chèvre Inconjugué ELISA, IHC, WB EB08711 (0.3µg/ml) staining of Jurkat lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected with chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$429.62
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-ABCD4 Antibody Titration:  1.25ug/ml  Positive Control:  HepG2 cell lysate ABCD4 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Lapin Inconjugué IHC, WB Immunohistochemical analysis of ABCD4 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of ABCD4 expression in Jurkat (A), Raji (B), THP1 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Chèvre Inconjugué ELISA, IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, IHC, WB Western Blot (WB) analysis of specific cells using ABCD4 Polyclonal Antibody. 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Cobaye Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, IHC, WB ABIN6274885 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6274885 staining HepG2 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails

anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 4 Anticorps mieux référencés

  1. Human Polyclonal ABCD4 Primary Antibody pour ELISA, WB - ABIN451659 : Asheuer, Bieche, Laurendeau, Moser, Hainque, Vidaud, Aubourg: Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy. dans Human molecular genetics 2005 (PubMed)

  2. Human Polyclonal ABCD4 Primary Antibody pour IHC, IHC (p) - ABIN4277208 : Coelho, Kim, Miousse, Fung, du Moulin, Buers, Suormala, Burda, Frapolli, Stucki, Nürnberg, Thiele, Robenek, Höhne, Longo, Pasquali, Mengel, Watkins, Shoubridge, Majewski, Rosenblatt, Fowler, Rutsch et al.: Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism. ... dans Nature genetics 2012 (PubMed)

Plus d’anticorps contre ATP-Binding Cassette, Sub-Family D (Ald), Member 4 partenaires d’interaction

Human ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4) interaction partners

  1. endogenous ABCD4 was localized to both lysosomes and the ER, and its lysosomal localization was disturbed by knockout of LMBRD1 (Montrer LMBRD1 Anticorps)

  2. Data suggest that ABCD4 lysosomal targeting depends on co-expression of and interaction with LMBRD1; mutations in LMBRD1 and ABCD4 that result in cobalamin metabolism disorders cblF and cblJ (or mutations in ATPase domain) disrupt interactions between LMBRD1 and ABCD4. (LMBRD1 = nuclear export signal-interacting protein; ABCD4 = ATP-binding cassette, sub-family D (ALD), member 4)

  3. ABCD1 (Montrer ABCD1 Anticorps) and ABCD2 (Montrer Abcd2 Anticorps) are involved in the transport of long and very long chain fatty acids (VLCFA) or their CoA-derivatives into peroxisomes with different substrate specificities, while ABCD3 (Montrer ABCD3 Anticorps) is involved in the transport of branched chain acyl-CoA (Montrer GNPAT Anticorps) into peroxisomes.ABCD4 is deduced to take part in the transport of vitamin B12 (Montrer NDUFB3 Anticorps) from lysosomes into the cytosol.

  4. Results propose a model whereby membrane-bound LMBD1 (Montrer LMBRD1 Anticorps) and ABCD4 facilitate the vectorial delivery of lysosomal vitamin B12 (Montrer NDUFB3 Anticorps) to cytoplasmic MMACHC (Montrer MMACHC Anticorps).

  5. mutations altering the putative ATPase (Montrer ATP13A2 Anticorps) domain of ABCD4 affect its function, suggesting that the ATPase (Montrer DNAH8 Anticorps) activity of ABCD4 may be involved in intracellular processing of vitamin B12 (Montrer NDUFB3 Anticorps).

  6. Defects in ABCB4 (Montrer ABCB4 Anticorps) have been found to cause progressive familial intrahepatic cholestasis type 3.

Mouse (Murine) ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4) interaction partners

  1. P70R resides in the ER but not the peroxisomal membranes, and the hydrophobic property of NH(2)-terminal region determines the subcellular localization of ABC (Montrer ABCB6 Anticorps) subfamily D (Montrer CYP Anticorps) proteins.

ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4) profil antigène

Profil protéine

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.

Gene names and symbols associated with ABCD4

  • ATP binding cassette subfamily D member 4 (ABCD4) anticorps
  • ATP binding cassette subfamily D member 4 (Abcd4) anticorps
  • ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4) anticorps
  • ATP-binding cassette, sub-family D (ALD), member 4 (abcd4) anticorps
  • ATP-binding cassette, sub-family D (ALD), member 4 (Abcd4) anticorps
  • ABC41 anticorps
  • ABCD4 anticorps
  • EST352188 anticorps
  • MAHCJ anticorps
  • P69r anticorps
  • P70R anticorps
  • P79R anticorps
  • PMP69 anticorps
  • Pxmp1l anticorps
  • zgc:153503 anticorps

Protein level used designations for ABCD4

69 kDa peroxisomal ABC-transporter , ATP-binding cassette sub-family D member 4 , PMP70-related protein , PXMP1-L , peroxisomal membrane protein 69 , ATP-binding cassette, sub-family D (ALD), member 4 , ATP-binding cassette, sub-family D, member 4 , PMP69 , peroxisomal membrane protein, 70 kDa-related , ATP-binding cassette sub-family D member 4-like

GENE ID SPECIES
5826 Homo sapiens
299196 Rattus norvegicus
528646 Bos taurus
423349 Gallus gallus
453032 Pan troglodytes
490781 Canis lupus familiaris
699380 Macaca mulatta
767748 Danio rerio
19300 Mus musculus
100412514 Callithrix jacchus
100450774 Pongo abelii
100479969 Ailuropoda melanoleuca
100722270 Cavia porcellus
100341975 Oryctolagus cuniculus
101106333 Ovis aries musimon
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