anti-Abelson Helper Integration Site 1 (AHI1) Anticorps

AHI1 is apparently required for both cerebellar and cortical development in humans. De plus, nous expédions AHI1 Kits (3) et AHI1 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
AHI1 54806 Q8N157
AHI1 52906  
AHI1 308923 Q6DTM3
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Top anti-AHI1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 53 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-Ahi1 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Rat Lung 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$242.88
Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Souris Souris Inconjugué ICC, IF, IP, IHC, WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$419.83
Détails
Humain Chèvre Inconjugué ELISA   100 μg Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Lapin Inconjugué IP, WB AHI1 MaxPab rabbit polyclonal antibody. Western Blot analysis of AHI1 expression in mouse testis. Immunoprecipitation of AHI1 transfected lysate using anti-AHI1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with AHI1 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Connectez-vous pour afficher 11 to 12 Days
$425.71
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: AHI1 Antibody [NBP2-15309] - Analysis of methanol-fixed HeLa, using antibody at 1:500 dilution. Immunohistochemistry-Paraffin: AHI1 Antibody [NBP2-15309] - Paraffin-embedded Colon ca, using antibody at 1:500 dilution. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$514.63
Détails
Humain Lapin Inconjugué WB Western Blot showing Ahi1 antibody used at a concentration of 1.0 ug/ml against Rat Lung Lysate 50 μg Connectez-vous pour afficher 6 to 8 Days
$473.93
Détails
Humain Lapin Inconjugué IHC (p), WB   50 μL Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails

AHI1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , , , ,
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Mouse (Murine)
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Rat (Rattus)


anti-AHI1 Anticorps mieux référencés

  1. Human Polyclonal AHI1 Primary Antibody pour ELISA, WB - ABIN250311 : Jiang, Hanna, Kaouass, Girard, Jolicoeur: Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrations. dans Journal of virology 2002 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal AHI1 Primary Antibody pour ELISA, WB - ABIN185303 : Dixon-Salazar, Silhavy, Marsh, Louie, Scott, Gururaj, Al-Gazali, Al-Tawari, Kayserili, Sztriha, Gleeson: Mutations in the AHI1 gene, encoding jouberin, cause Joubert syndrome with cortical polymicrogyria. dans American journal of human genetics 2004 (PubMed)
    Show all 5 Pubmed References

Plus d’anticorps contre AHI1 partenaires d’interaction

Zebrafish Abelson Helper Integration Site 1 (AHI1) interaction partners

  1. We cloned the full cDNA sequence of Ahi-1 homologous in zebrafish.RT-PCR reveal that ZAhi-1 expressed highest in the mature gonad. In situ hybridization results of zebrafish gonad show that ZAhi-1 only expressed in the early stages' gamete cells.[ZAhi-1]

  2. a role for Ahi1 in epithelial cell organization and ciliary formation and explain the ciliopathy phenotype of AHI1 mutations in man.

  3. Results describe spatiotemporal expression patterns of AHI1 and orthologs throughout development, in human, mouse, and zebrafish, and suggest roles for AHI1 in neurodevelopmental processes behind most of the neuroanatomical defects in Joubert syndrome.

Human Abelson Helper Integration Site 1 (AHI1) interaction partners

  1. Results identified 74 somatic insertions in squamous cell carcinoma of the esophagus (SCC (Montrer CYP11A1 Anticorps)); 12 of them appeared to be somatic, not genetically inherited, and sub-clonal in the adjacent normal esophagus, while clonal in the tumor. These results indicate that L1 retrotransposition is active in SCC (Montrer CYP11A1 Anticorps) of the esophagus and that insertion events are present in histologically NE that expands clonally in the subsequent tumors.

  2. a new AHI-1-BCR-ABL (Montrer ABL1 Anticorps)-DNM2 (Montrer DNM2 Anticorps) protein complex was uncovered, which regulates leukemic properties of these cells through a unique mechanism of cellular endocytosis and ROS (Montrer ROS1 Anticorps)-mediated autophagy. Thus, targeting this complex may facilitate eradication of LSCs for curative therapies

  3. introduction of equivalent stop codons in the full-length human L1 sequence leads to the expression of truncated ORF1 proteins.

  4. Aicardi-Goutieres syndrome protein TREX1 (Montrer TREX1 Anticorps) suppresses L1 and maintains genome integrity through exonuclease (Montrer EXO1 Anticorps)-independent ORF1p depletion.

  5. We observed that a cis (Montrer CISH Anticorps)-eQTL (Montrer EQTN Anticorps) of AHI1, rs11154801, showed significant association with AHI1 expression. Genetic evidence exhibited that rs11154801 was significantly associated with schizophrenia risk in both the discovery and the replication sample. These results suggested that AHI1 is likely a risk gene for schizophrenia, at least in European populations.

  6. We examined a Chinese strabismus (Montrer VANGL2 Anticorps) pedigree with the parents unaffected and 2 offspring affected. Whole-exome sequencing and bioinformatics filtering identified 2 variants including Abelson helper integration site 1 (AHI1) gene and nebulin (NEB (Montrer NEB Anticorps)) gene. The variant in the AHI1 gene, c.A3257G (p.E1086G), and the altered amino acid had a damaging effect on the encoded protein predicted by Polyphen2.

  7. Homozygosity mapping and WES in the only other reported JBTS family with a homozygous C-terminal truncation (p.Trp1088Leufs*16) confirmed AHI1 as disease gene.

  8. Two SNPs of AHI1 (rs7750586 and rs9647635) were associated with clinical improvement of negative symptoms in the allelic analysis, although in the genotypic analysis, only trends of association were found for the same SNPs.

  9. Joubert syndrome-associated missense mutations alter the subcellular distribution and protein interactions of AHI1.

  10. The WD40-repeat domain of AHI-1 interacts with BCR-ABL, whereas the N-terminal region interacts with JAK2; loss of these interactions statistically significantly increased the IM sensitivity of CML cells.

Mouse (Murine) Abelson Helper Integration Site 1 (AHI1) interaction partners

  1. The current research describes multi-faceted effort to link early variations in Ahi1 expression with long-term consequences for functional brain networks and cognitive-emotional phenotypes.

  2. Our findings suggest that Ahi1 KO mice can be used for studying the mechanisms of depression and screening therapeutic targets.

  3. Jouberin is expressed in mESCs and localized at the primary cilium. Jouberin controls mouse embryonic stem cells early neural differentiation.

  4. Results suggest that under-expression of the Ahi1 gene during neurodevelopment brings about relative resilience to various stressors during adulthood

  5. The results of this study suggest that Cend1 (Montrer CEND1 Anticorps) is involved in Ahi1 mutation-induced neuropathology.

  6. Hypothalamic Ahi1 functions as a sensor of insulin (Montrer INS Anticorps) signaling.

  7. a role for Ahi1 in epithelial cell organization and ciliary formation and explain the ciliopathy phenotype of AHI1 mutations in man.

  8. Results indicate that the Hap1 (Montrer HAP1 Anticorps)-Ahi1 complex in the brainstem works as a sensor for insulin (Montrer INS Anticorps) signals in feeding control.

  9. Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB (Montrer NTRK2 Anticorps) signaling with a depressive phenotype.

  10. The retinal degeneration observed in Ahi1(-/-) mice recapitulates aspects of the retinal phenotype observed in patients with Joubert syndrome and suggests the importance of Ahi1 in photoreceptor function.

AHI1 profil antigène

Profil protéine

This gene is apparently required for both cerebellar and cortical development in humans. This gene mutations cause specific forms of Joubert syndrome-related disorders. Joubert syndrome (JS) is a recessively inherited developmental brain disorder with several identified causative chromosomal loci. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with AHI1

  • Abelson helper integration site 1 (AHI1) anticorps
  • Abelson helper integration site 1 (ahi1) anticorps
  • Abelson helper integration site 1 (Ahi1) anticorps
  • 1700015F03Rik anticorps
  • Ahi-1 anticorps
  • AHI1 anticorps
  • D10Bwg0629e anticorps
  • dJ71N10.1 anticorps
  • JBTS3 anticorps
  • ORF1 anticorps

Protein level used designations for AHI1

Abelson helper integration site 1 , jouberin , ZAhi-1 , jouberin-like , abelson helper integration site 1 protein homolog , contatins SH3 and WD40 domains , abelson helper integration site 1 protein

GENE ID SPECIES
472132 Pan troglodytes
562701 Danio rerio
706412 Macaca mulatta
100073172 Equus caballus
100408138 Callithrix jacchus
100339239 Oryctolagus cuniculus
100552011 Anolis carolinensis
100590801 Nomascus leucogenys
100617670 Monodelphis domestica
54806 Homo sapiens
52906 Mus musculus
308923 Rattus norvegicus
476212 Canis lupus familiaris
100514806 Sus scrofa
528398 Bos taurus
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