anti-Aconitase 2, Mitochondrial (ACO2) Anticorps

The protein encoded by ACO2 belongs to the aconitase/IPM isomerase family. De plus, nous expédions ACO2 Kits (30) et ACO2 Protéines (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ACO2 50 Q99798
ACO2 11429 Q99KI0
ACO2 79250 Q9ER34
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Top anti-ACO2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 134 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-ACO2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>721_B cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-ACO2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human heart 100 μL Connectez-vous pour afficher 2 to 3 Days
$319.00
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of anti-ACO2 Pab (ABIN388648) in mouse heart(left) and 293 (right) tissue lysates (35 µg/lane). ACO2(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Perfused isolated rat heart whole tissue lysate was lysed with either A) 50 mM Tris-HCl, 150 mM NaCl, 1 mM EDTA, 1% NP-40, 0.1% SDS, 0.5% Na-deoxycholate, 1 mM Na3VO4, 20 mM NaF, 1 mM PMSF, 5 v/v % protease inhibitor cocktail or B) T-PER Tissue Protein Extraction Reagent [# 785101. Pierce], containing 1mM Na3VO4, 20 mM NaF, 5 v/v % protease inhibitor cocktail (Sigma). PVDF membrane was incubated in primary Ab [rabbit polyclonal antibody against ACO2 (Center) (ABIN388648). Solution: 1:1000 diluted in 5% NFM TBS-T 0,05 for overnight (15 hrs) at 4 °. Data courtesy of Boglarka Laczy M.D., Division of Cardiovascular Disease, Dept. of Medicine, University of Alabama at Birmingham. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Chèvre Inconjugué ELISA, IF, IHC, WB (0.01µg/ml) staining of Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$429.62
Détails
Humain Chèvre Inconjugué IHC, ELISA, WB (0.01µg/ml) staining of Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$429.62
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of Aconitase 2 expression in rat skeletal muscle extract ( Lane 1), mouse brain extract ( Lane 2) and HELA whole cell lysates ( Lane 3). Aconitase 2 at 85KD was detected using rabbit anti- Aconitase 2 Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Western Blot: Aconitase 2 Antibody [NBP1-90264] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells).Lane 3: PC12 cell lysate (Pheochromocytoma of rat adrenal medulla) Immunocytochemistry/Immunofluorescence: Aconitase 2 Antibody [NBP1-90264] - Staining of human cell line U-2 OS shows positivity in mitochondria. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), IP, WB Western Blot: Aconitase 2 Antibody [NBP1-32781] - Sample (30 ug of whole cell lysate) A: 293T B: A431 7.5% SDS PAGE, antibody diluted at 1:10000. Immunocytochemistry/Immunofluorescence: Aconitase 2 Antibody [NBP1-32781] - Analysis of methanol-fixed HeLa, using antibody at 1:500 dilution. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$514.63
Détails
Humain Souris Inconjugué IF, IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails

anti-ACO2 Anticorps mieux référencés

  1. Human Polyclonal ACO2 Primary Antibody pour IHC (p), WB - ABIN388648 : OConnell, Gannon, Doran, Ohlendieck: Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle. dans International journal of molecular medicine 2007 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal ACO2 Primary Antibody pour EIA, WB - ABIN357262 : Geurts van Kessel, Westerveld, de Groot, Meera Khan, Hagemeijer: Regional localization of the genes coding for human ACO2, ARSA, and NAGA on chromosome 22. dans Cytogenetics and cell genetics 1981 (PubMed)
    Show all 8 Pubmed References

  3. Cow (Bovine) Polyclonal ACO2 Primary Antibody pour WB - ABIN2786627 : Yu, Costello, Feng, Franklin: Characterization of the mitochondrial aconitase promoter and the identification of transcription factor binding. dans The Prostate 2006 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal ACO2 Primary Antibody pour ICC, IF - ABIN4277666 : Cantu, Fulton, Drechsel, Patel: Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂. dans Journal of neurochemistry 2011 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal ACO2 Primary Antibody pour ICC, IF - ABIN442737 : Tammineni, Anugula, Mohammed, Anjaneyulu, Larner, Sepuri: The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain. dans The Journal of biological chemistry 2013 (PubMed)

  6. Human Polyclonal ACO2 Primary Antibody pour IHC (p), WB - ABIN391809 : Dey, Guha, Alam, Goyal, Bindu, Pal, Maity, Mitra, Bandyopadhyay: Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis. dans Free radical biology & medicine 2009 (PubMed)

  7. Human Polyclonal ACO2 Primary Antibody pour ELISA, IHC - ABIN4277664 : Bota, Davies: Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism. dans Nature cell biology 2002 (PubMed)

  8. Cow (Bovine) Polyclonal ACO2 Primary Antibody pour IHC, WB - ABIN2786628 : Scheving, Wittig, Heide, Albuquerque, Steger, Brandt, Tegeder: Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve. dans Journal of proteomics 2012 (PubMed)

  9. Human Monoclonal ACO2 Primary Antibody pour ELISA - ABIN513071 : Lin, Brownsey, MacLeod: Regulation of mitochondrial aconitase by phosphorylation in diabetic rat heart. dans Cellular and molecular life sciences : CMLS 2009 (PubMed)

Plus d’anticorps contre ACO2 partenaires d’interaction

Arabidopsis thaliana Aconitase 2, Mitochondrial (ACO2) interaction partners

  1. The identification of ACO1 (Montrer ACO1 Anticorps), ACO2, and ACO3 in A. thaliana is reported, and it was demonstrated that, in plants, the cytosolic ACOs are not converted into iron regulatory proteins.

Human Aconitase 2, Mitochondrial (ACO2) interaction partners

  1. Aco2 activity correlated significantly with motor score, independence scale, and functional capacity of the Unified Huntington's Disease Rating Scale as well as disease duration. Our study provides a potential biomarker to assess the disease status of HD patients and PreHD carriers.

  2. Results suggest that ACO2 activity is reduced in peripheral lymphocytes of subjects with Alzheimer's disease and mild cognitive impairment and correlates with antioxidant protection

  3. Our study shows that autosomal recessive ACO2 mutations can cause either isolated or syndromic optic neuropathy.

  4. immunofluorescence staining localized ACO2 to the human sperm mid-piece. By immunoblotting, we demonstrated that the level of ACO2 protein in asthenozoospermic samples was significantly decreased compared with that in normal fertile men

  5. Ogg1 (Montrer OGG1 Anticorps) chaperoning of Aco-2 in preventing oxidant-mediated mtDNA damage and apoptosis may afford an innovative target for the molecular events underlying oxidant-induced toxicity.

  6. Hypoxia upregulates the gene expression of mitochondrial aconitase in prostate carcinoma cells

  7. Gastric cancer patients with lower ACO2 expression have a shorter survival time than those with higher ACO2 expression.

  8. Homozygosity mapping followed by whole-exome sequencing disclosed a Ser112Arg mutation in ACO2.

  9. these results suggest that p53 downregulation of mACON gene expression in human prostate carcinoma cells may not occur through the putative consensus p53 response elements found within the mACON promoter.

  10. Lon (Montrer LONP1 Anticorps) protease selectively recognizes and degrades the oxidized, hydrophobic form of aconitase (Montrer ACO1 Anticorps) after mild oxidative modification, but that severe oxidation results in aconitase (Montrer ACO1 Anticorps) aggregation, which makes it a poor substrate for Lon (Montrer LONP1 Anticorps).

Mouse (Murine) Aconitase 2, Mitochondrial (ACO2) interaction partners

  1. Activation of mitochondrial aconitase is acetylation-dependent.

  2. Ogg1 (Montrer OGG1 Anticorps) chaperoning of Aco-2 in preventing oxidant-mediated mtDNA damage and apoptosis may afford an innovative target for the molecular events underlying oxidant-induced toxicity.

  3. IRP-1 (Montrer ACO1 Anticorps),-2 are indispensable for regulation of mammalian iron homeostasis at the post-implantation stage of murine embryonic development

  4. aconitase activity can be regulated by at least two mechanisms: oxidation/reduction and phosphorylation/dephosphorylation

Pig (Porcine) Aconitase 2, Mitochondrial (ACO2) interaction partners

  1. study examined the sites and mechanisms of aconitase inactivation by peroxynitrite (ONOO-), a strong oxidant and nitrating agent readily formed from superoxide anion and nitric oxide generated by mitochondria

ACO2 profil antigène

Profil protéine

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

Gene names and symbols associated with ACO2

  • aconitase 2 (ACO2) anticorps
  • aconitase 2 S homeolog (aco2.S) anticorps
  • aconitate hydratase, mitochondrial (Bm1_07420) anticorps
  • aconitase, mitochondrial (aco2) anticorps
  • mitochondrial aconitate hydratase (ach1) anticorps
  • aconitase 2 (aco2) anticorps
  • aconitase 2, mitochondrial (Aco2) anticorps
  • aconitase 2 (Aco2) anticorps
  • aconitase 2, mitochondrial (aco2) anticorps
  • Probable aconitate hydratase, mitochondrial (aco-2) anticorps
  • Aco-2 anticorps
  • Aco3 anticorps
  • aconitase 2 anticorps
  • ACONM anticorps
  • cb1017 anticorps
  • D10Wsu183e anticorps
  • DDBDRAFT_0206187 anticorps
  • DDBDRAFT_0230168 anticorps
  • DDB_0206187 anticorps
  • DDB_0230168 anticorps
  • F10M23.310 anticorps
  • F10M23_310 anticorps
  • ICRD anticorps
  • wu:fa10e03 anticorps
  • wu:fb69g04 anticorps
  • wu:fc20c11 anticorps

Protein level used designations for ACO2

aconitate hydratase, mitochondrial , mitochondrial aconitate hydratase , aconitase 2, mitochondrial , aconitate hydratase, mitochondrial-like , citrate hydro-lyase , mitochondrial aconitase (nuclear aco2 gene) , heart aconitase

GENE ID SPECIES
374009 Gallus gallus
444692 Xenopus laevis
6096411 Brugia malayi
8621690 Dictyostelium discoideum AX4
9617127 Volvox carteri f. nagariensis
100444223 Pongo abelii
496933 Xenopus (Silurana) tropicalis
707441 Macaca mulatta
828805 Arabidopsis thaliana
100352714 Oryctolagus cuniculus
100389367 Callithrix jacchus
100568244 Anolis carolinensis
100598337 Nomascus leucogenys
50 Homo sapiens
11429 Mus musculus
79250 Rattus norvegicus
396999 Sus scrofa
280976 Bos taurus
474487 Canis lupus familiaris
322670 Danio rerio
176121 Caenorhabditis elegans
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