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ACRV1 encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm.
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Human Monoclonal ACRV1 Primary Antibody pour ICC, FACS - ABIN302102
Pavlásek, Peknicová, Ulcová-Gallová, Nováková, Reischig, Micanová, Rokyta: [Significance of determination of intra-acrosomal proteins and sperm antibodies in human reproduction]. dans Ceská gynekologie / Ceská lékarská spolecnost J. Ev. Purkyne 2004
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Human Monoclonal ACRV1 Primary Antibody pour ICC, FACS - ABIN1302844
Peknicová, Kyselová, Buckiová, Boubelík: Effect of an endocrine disruptor on mammalian fertility. Application of monoclonal antibodies against sperm proteins as markers for testing sperm damage. dans American journal of reproductive immunology (New York, N.Y. : 1989) 2002
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Guinea Pig Polyclonal ACRV1 Primary Antibody pour WB - ABIN2785464
Reddi, Shore, Acharya, Herr: Transcriptional regulation of spermiogenesis: insights from the study of the gene encoding the acrosomal protein SP-10. dans Journal of reproductive immunology 2001
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Dog (Canine) Monoclonal ACRV1 Primary Antibody pour ICC, WB - ABIN93928
Geussová, P?knicová, Capková, Kaláb, Moos, Philimonenko, Hozák: Monoclonal antibodies to canine intra-acrosomal sperm proteins recognizing acrosomal status during capacitation and acrosome reaction. dans Andrologia 1997
Human Polyclonal ACRV1 Primary Antibody pour IHC, IHC (p) - ABIN4327338
Djureinovic, Fagerberg, Hallström, Danielsson, Lindskog, Uhlén, Pontén: The human testis-specific proteome defined by transcriptomics and antibody-based profiling. dans Molecular human reproduction 2014
ACRV1 protein was predominantly located in round and elongated spermatids in testes, indicating that ACRV1 may play an important role in mammalian spermatogenesis
Loss of ACRV1 led to the progression of pancreatic intraductal carcinoma in mouse models.
Using RT-PCR analysis of mouse ACRV1, we determined that ACRV1 was expressed specifically in the testis, and its expression began at days 35.
TDP-43 (Montrer TARDBP Anticorps) is a transcriptional repressor and that it regulates spatiotemporal expression of the acrv1 gene during spermatogenesis.
A novel CpG-free vertebrate insulator silences the testis-specific (Montrer AIF1 Anticorps) SP-10 gene in somatic tissues: role for TDP-43 (Montrer TARDBP Anticorps) in insulator function.
we propose that NF45 (Montrer ILF2 Anticorps) and NF90 have the potential to activate SP-10 gene transcription, and that a chromatin modification event must occur first in order to provide access to these transcription factors.
This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration. Alternatively spliced transcript variants have been described.
acrosomal vesicle protein 1
, acrosomal protein SP-10
, sperm protein 10
, sperm membrane protein