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The protein encoded by Actl7b is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins.
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Human Polyclonal Actl7b Primary Antibody pour IHC, IHC (p) - ABIN4278151
Djureinovic, Fagerberg, Hallström, Danielsson, Lindskog, Uhlén, Pontén: The human testis-specific proteome defined by transcriptomics and antibody-based profiling. dans Molecular human reproduction 2014
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Rat (Rattus) Polyclonal Actl7b Primary Antibody pour ELISA, WB - ABIN252913
Chadwick, Mull, Helbling, Gill, Leyne, Robbins, Pinkett, Makalowska, Maayan, Blumenfeld, Axelrod, Brownstein, Gusella, Slaugenhaupt: Cloning, mapping, and expression of two novel actin genes, actin-like-7A (ACTL7A) and actin-like-7B (ACTL7B), from the familial dysautonomia candidate region on 9q31. dans Genomics 1999
results suggest that T-ACTINs play important roles in sperm function and in the specific morphogenesis of spermatozoa during spermiogenesis
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
actin-like protein 7B
, actin-like 7B
, actin-like 7-beta
, t-actin 1
, testis-specific actin-1
, actin-like protein 7B-like