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The protein encoded by ACSL5 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. De plus, nous expédions ACSL5 Protéines (9) et et beaucoup plus de produits pour cette protéine.
Showing 10 out of 69 products:
Human Monoclonal ACSL5 Primary Antibody pour IHC (p), IP - ABIN565656
Mashima, Sato, Sugimoto, Tsuruo, Seimiya: Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions. dans Oncogene 2009
Show all 4 Pubmed References
Human Polyclonal ACSL5 Primary Antibody pour ELISA, WB - ABIN251402
Obermüller, Keith, Kopitz, Autschbach, Schirmacher, Gassler: Coeliac disease is associated with impaired expression of acyl-CoA-synthetase 5. dans International journal of colorectal disease 2006
Human Polyclonal ACSL5 Primary Antibody pour IHC, IHC (p) - ABIN4892435
Klett, Chen, Edin, Li, Ilkayeva, Zeldin, Newgard, Coleman: Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion. dans The Journal of biological chemistry 2013
Human Polyclonal ACSL5 Primary Antibody pour WB - ABIN5663854
Yu, Zhang, Cui, Wang, Na, Zhu, Li, Xu, Yang, Christian, Liu: Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment. dans Biochimica et biophysica acta 2015
our study has demonstrated that ACS5 expression was increased in colorectal cancer (CRC (Montrer CALR Anticorps)) cells and CRC (Montrer CALR Anticorps) tissues and its upregulation closely correlated to poor tumor differentiation and excess muscular layer in patients with CRC (Montrer CALR Anticorps)
These results suggest that ACSL1 (Montrer Acsl1 Anticorps), ACSL4 (Montrer ACSL4 Anticorps) and ACSL5 expression is regulated by ER signaling pathways and ACSL5 is a potential novel biomarker for predicting prognosis of breast cancer patients.
Functional variant (rs2256368:A>G) affecting ACSL5 exon 20 skipping was identified as a causal factor linked to the migraine-associated rs12355831:A>G, suggesting that the activation of long-chain fatty acids by the spliced ACSL5-Delta20 molecules is involved in migraine pathology.
colorectal adenocarcinomas with low (n=41; group 1) or high (n=31; group 2) ACSL5 levels were identified. In a one-year follow-up, tumour recurrence was significantly increased in group 1.
ACSL5 mediates antiproliferative activities via Wnt2B (Montrer WNT2B Anticorps) palmitoylation with diminished Wnt (Montrer WNT2 Anticorps) activity. The molecular pathway is probably relevant for intestinal homeostasis, overwhelmed by other pathways in carcinogenesis.
Uncoupling of ACSL5 and mitochondrial mortalin (Montrer HSPA9 Anticorps) by mutated TP53 (Montrer TP53 Anticorps) could be important in colorectal carcinogenesis.
Down-regulation of ACSL5 is associated with colorectal cancer.
Levels of acyl-coenzyme A (Montrer SOAT2 Anticorps) synthetase 5 in urothelial cells and corresponding neoplasias reflect cellular differentiation.
High ACSL5 transcript levels associate with systemic lupus erythematosus and apoptosis in Jurkat T lymphocytes and peripheral blood cells
The data strongly indicate that human but not rat acyl-CoA synthetase 5 is sensitive to triacsin C and does not compensate for other triacsin C-sensitive ACSL isoforms.
Acsl5 is a major activator of dietary long chain fatty acids , yet in Acsl5 KO mice residual ACS activity is sufficient for maintaining a normal long chain fatty acids absorption.
Acyl-CoA synthetase 2 has a role in fatty acid internalization and neurite outgrowth
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.
acyl-CoA synthetase long-chain family member 5
, long-chain-fatty-acid--CoA ligase 5
, acyl-CoA synthetase 5
, long-chain-fatty-acid--CoA ligase 5-like
, FACL5 for fatty acid coenzyme A ligase 5
, LACS 5
, fatty acid coenzyme A ligase 5
, fatty-acid-Coenzyme A ligase, long-chain 5
, long-chain acyl-CoA synthetase 5
, long-chain fatty acid coenzyme A ligase 5
, fatty acid Coenzyme A ligase, long chain 5