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ACOT11 encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A.
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The N-terminal region of human fat inducible thioesterase (Montrer FASN Anticorps) variant 2 constitutes a mitochondrial location signal sequence, which undergoes mitochondrion-dependent posttranslational cleavage.
BFIT supports the transition of thermogenic brown adipose tissue towards increased metabolic activity, probably through alteration of intracellular fatty acyl-CoA (Montrer GNPAT Anticorps) concentration.
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.
START domain containing 14
, StAR-related lipid transfer (START) domain containing 14
, acyl-CoA thioester hydrolase 11
, acyl-coenzyme A thioesterase 11
, adipose-associated thioesterase
, brown fat-inducible thioesterase
, thioesterase superfamily member 1
, thioesterase, adipose associated
, acyl-CoA thioesterase 11