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anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 Anticorps

26 Résultats:

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) (AA 1-664) anticorps Primary Antibody

APPL2 Reactivité: Humain IF, WB Hôte: Souris Polyclonal unconjugated
Pubmed 1
N° du produit ABIN527414
601,20 €
Plus frais de livraison 40,00 € et TVA
50 μg
local_shipping Destination: France
Envoi sous 8 à 9 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) (AA 174-273) anticorps Primary Antibody

APPL2 Reactivité: Humain IF, ELISA, WB Hôte: Souris Monoclonal 1C10 unconjugated
N° du produit ABIN527415
601,20 €
Plus frais de livraison 40,00 € et TVA
100 μg
local_shipping Destination: France
Envoi sous 8 à 9 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) (AA 124-152), (N-Term) anticorps Primary Antibody

APPL2 Reactivité: Humain WB Hôte: Lapin Polyclonal RB37296 unconjugated
N° du produit ABIN1539001
422,72 €
Plus frais de livraison 40,00 € et TVA
400 μL (More quantities available)
local_shipping Destination: France
Envoi sous 14 à 16 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) anticorps Primary Antibody

APPL2 Reactivité: Humain ELISA, IHC, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5623056
618,54 €
Plus frais de livraison 40,00 € et TVA
100 μg
local_shipping Destination: France
Envoi sous 13 à 16 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) anticorps Primary Antibody

APPL2 Reactivité: Humain, Souris, Rat ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5702507
378,18 €
Plus frais de livraison 40,00 € et TVA
100 μg
local_shipping Destination: France
Envoi sous 7 à 10 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) (C-Term) anticorps Primary Antibody

APPL2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5516603
486,06 €
Plus frais de livraison 40,00 € et TVA
100 μL
local_shipping Destination: France
Envoi sous 6 à 8 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) (PH domain) anticorps Primary Antibody

APPL2 Reactivité: Humain IP, IHC, ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2203417
596,85 €
Plus frais de livraison 40,00 € et TVA
100 μg
local_shipping Destination: France
Envoi sous 15 à 21 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) (AA 174-274), (PH domain) anticorps Primary Antibody

APPL2 Reactivité: Humain ELISA, WB Hôte: Souris Monoclonal 1C10 unconjugated
N° du produit ABIN2203418
707,23 €
Plus frais de livraison 40,00 € et TVA
100 μg
local_shipping Destination: France
Envoi sous 15 à 21 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) (AA 1-664), (PH domain) anticorps Primary Antibody

APPL2 Reactivité: Humain IF, WB Hôte: Souris Polyclonal unconjugated
N° du produit ABIN2203419
707,23 €
Plus frais de livraison 40,00 € et TVA
50 μg
local_shipping Destination: France
Envoi sous 15 à 21 jours ouvrables
N° du produit ABIN2203416
741,32 €
Plus frais de livraison 40,00 € et TVA
100 μL
local_shipping Destination: France
Envoi sous 15 à 21 jours ouvrables
  • Type Primary
    • Primary
  • Target Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2)
    • Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4
    • tau Protein
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Nuclear Factor-kB p65 (NFkBP65)
    • Estrogen Receptor 1 (ESR1)
    • Albumin (ALB)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • CD8a Molecule (CD8A)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • CD19 Molecule (CD19)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Integrin alpha M (ITGAM)
    • CD3 epsilon (CD3E)
    • Tuberous Sclerosis 2 (TSC2)
    • CD44
    • Interleukin 2 Receptor, alpha (IL2RA)
    • CD3
    • Hemagglutinin (HA)
    • CD8
    • Interleukin 6 (IL6)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Histone H4
    • Jun Proto-Oncogene (JUN)
    • Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1)
    • Myc Proto-Oncogene protein (MYC)
    • CD5
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • CD34
    • Interleukin 2 (IL2)
    • Catenin, beta (CATNB)
    • CD14
    • Vimentin (VIM)
    • Mucin 1 (MUC1)
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Insulin Receptor Substrate 1 (IRS1)
    • Keratin 18 (KRT18)
    • Amyloid beta (A4) Precursor Protein (APP)
    • Intercellular Adhesion Molecule 1 (ICAM1)
  • Application
    • Western Blotting (WB)
    • ELISA
    • Immunofluorescence (IF)
    • Immunohistochemistry (IHC)
    • Immunoprecipitation (IP)
  • Réactivité
    • Humain
    • Souris
    • Rat
  • Cité dans publications
  • Images disponible
  • Preservative free only
  • Hote
    • Lapin
    • Souris
  • Clonalité
    • Polyclonal
    • Monoclonal
  • Clone
    • 1C10
    • RB37296
  • Epitope
    • AA 124-152
    • N-Term
    • AA 122-152
    • PH domain
    • AA 1-664
    • AA 174-274
    • AA 174-273
    • AA 619-662
    • C-Term
  • Conjugué
    • Inconjugué
    • APC
    • Alkaline Phosphatase (AP)
    • Biotin
    • FITC
    • HRP
    • PE
  • Isotype
    • IgG
    • IgG2b kappa
    • Ig Fraction
  • Format
    • Liquid

Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) profil antigène

Profil protéine

The protein encoded by this gene is one of two effectors of the small GTPase RAB5A/Rab5, which are involved in a signal transduction pathway. Both effectors contain an N-terminal Bin/Amphiphysin/Rvs (BAR) domain, a central pleckstrin homology (PH) domain, and a C-terminal phosphotyrosine binding (PTB) domain, and they bind the Rab5 through the BAR domain. They are associated with endosomal membranes and can be translocated to the nucleus in response to the EGF stimulus. They interact with the NuRD/MeCP1 complex (nucleosome remodeling and deacetylase /methyl-CpG-binding protein 1 complex) and are required for efficient cell proliferation. A chromosomal aberration t(12\;22)(q24.1\;q13.3) involving this gene and the PSAP2 gene results in 22q13.3 deletion syndrome, also known as Phelan-McDermid syndrome.

Gene names and symbols associated with APPL2

  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (Appl2) anticorps
  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (APPL2) anticorps
  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 L homeolog (appl2.L) anticorps
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (appl2) anticorps
  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (appl2) anticorps
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (Appl2) anticorps
  • APPL2 anticorps
  • Dip3b anticorps
  • DIP13B anticorps
  • MGC84621 anticorps
  • RGD1563028 anticorps

Protein level used designations for APPL2

DCC-interacting protein 13-beta , adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 , amyloid beta (A4) precursor-like protein 2 , DIP13 beta , adapter protein containing PH domain, PTB domain and leucine zipper motif 2 , Dip3 beta , dip13-beta

GENE ID SPECIES
362860 Rattus norvegicus
418075 Gallus gallus
447596 Xenopus laevis
515605 Bos taurus
100000135 Danio rerio
100127202 Xenopus (Silurana) tropicalis
100545199 Meleagris gallopavo
100563730 Anolis carolinensis
100604575 Nomascus leucogenys
55198 Homo sapiens
216190 Mus musculus

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