anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 Anticorps

The protein encoded by APPL2 is one of two effectors of the small GTPase RAB5A/Rab5, which are involved in a signal transduction pathway.

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Réactivité
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Clone
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Conjugué
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31 Produits
ReactivitéHumain
Application IF, ELISA, WB
Détails de la commande Cat. No. ABIN527415
$440.00
100 μg
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain
Application IF, WB
Détails de la commande Cat. No. ABIN527414
$440.00
50 μg
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain
Application ELISA, IHC, WB
Détails de la commande Cat. No. ABIN5623056
$429.86
100 μg
Plus shipping costs $45.00
Envoi sous 9 à 11 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application WB
Détails de la commande Cat. No. ABIN6292794
$309.73
50 μL
Plus shipping costs $45.00
Envoi sous 11 à 13 jours ouvrables
ReactivitéHumain
Application WB
Détails de la commande Cat. No. ABIN5535840
$550.00
400 μL
Plus shipping costs $45.00
Envoi sous 2 à 3 jours ouvrables
ReactivitéHumain
Application WB
Détails de la commande Cat. No. ABIN2999473
$590.93
Plus shipping costs $45.00
Envoi sous 11 à 16 jours ouvrables
ReactivitéHumain
Application WB
Détails de la commande Cat. No. ABIN5516603
$229.00
100 μL
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Envoi sous 2 à 3 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application ELISA, WB
Détails de la commande Cat. No. ABIN5702507
$380.00
100 μg
Plus shipping costs $45.00
Envoi sous 13 à 16 jours ouvrables
ReactivitéHumain
Application IHC, ELISA, WB
Détails de la commande Cat. No. ABIN1855826
$436.16
100 μg
Plus shipping costs $45.00
Envoi sous 11 à 16 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application ELISA, WB
Détails de la commande Cat. No. ABIN5916277
$492.44
100 μg
Plus shipping costs $45.00
Envoi sous 11 à 18 jours ouvrables
ReactivitéHumain
Application WB
Détails de la commande Cat. No. ABIN1807972
$493.17
400 μL
Plus shipping costs $45.00
Envoi sous 11 à 14 jours ouvrables
ReactivitéHumain
Application IP, IHC, ELISA, WB
Détails de la commande Cat. No. ABIN2203417
$518.57
100 μg
Plus shipping costs $45.00
Envoi sous 11 à 16 jours ouvrables
ReactivitéHumain
Application ELISA, WB
Détails de la commande Cat. No. ABIN2203418
$625.43
100 μg
Plus shipping costs $45.00
Envoi sous 11 à 16 jours ouvrables
ReactivitéHumain
Application IF, WB
Détails de la commande Cat. No. ABIN2203419
$625.43
50 μg
Plus shipping costs $45.00
Envoi sous 11 à 16 jours ouvrables
ReactivitéSouris
Application IP, WB
Détails de la commande Cat. No. ABIN2203416
$658.43
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 16 jours ouvrables
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Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) profil antigène

Profil protéine

The protein encoded by this gene is one of two effectors of the small GTPase RAB5A/Rab5, which are involved in a signal transduction pathway. Both effectors contain an N-terminal Bin/Amphiphysin/Rvs (BAR) domain, a central pleckstrin homology (PH) domain, and a C-terminal phosphotyrosine binding (PTB) domain, and they bind the Rab5 through the BAR domain. They are associated with endosomal membranes and can be translocated to the nucleus in response to the EGF stimulus. They interact with the NuRD/MeCP1 complex (nucleosome remodeling and deacetylase /methyl-CpG-binding protein 1 complex) and are required for efficient cell proliferation. A chromosomal aberration t(12\;22)(q24.1\;q13.3) involving this gene and the PSAP2 gene results in 22q13.3 deletion syndrome, also known as Phelan-McDermid syndrome.

Gene names and symbols associated with APPL2

  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (Appl2) anticorps
  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (APPL2) anticorps
  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 L homeolog (appl2.L) anticorps
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (appl2) anticorps
  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (appl2) anticorps
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (Appl2) anticorps
  • APPL2 anticorps
  • Dip3b anticorps
  • DIP13B anticorps
  • MGC84621 anticorps
  • RGD1563028 anticorps

Protein level used designations for APPL2

DCC-interacting protein 13-beta , adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 , amyloid beta (A4) precursor-like protein 2 , DIP13 beta , adapter protein containing PH domain, PTB domain and leucine zipper motif 2 , Dip3 beta , dip13-beta

GENE ID SPECIES
362860 Rattus norvegicus
418075 Gallus gallus
447596 Xenopus laevis
515605 Bos taurus
100000135 Danio rerio
100127202 Xenopus (Silurana) tropicalis
100545199 Meleagris gallopavo
100563730 Anolis carolinensis
100604575 Nomascus leucogenys
55198 Homo sapiens
216190 Mus musculus
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