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anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 Anticorps

The protein encoded by APPL2 is one of two effectors of the small GTPase RAB5A/Rab5, which are involved in a signal transduction pathway.

26 Résultats:

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) (AA 1-664) anticorps Primary Antibody

APPL2 Reactivité: Humain IF, WB Hôte: Souris Polyclonal
Pubmed 1
N° du produit ABIN527414
$440.00
Plus shipping costs $45.00
50 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 à 12 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) (AA 174-273) anticorps Primary Antibody

APPL2 Reactivité: Humain IF, ELISA, WB Hôte: Souris Monoclonal 1C10
N° du produit ABIN527415
$440.00
Plus shipping costs $45.00
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 à 12 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) anticorps Primary Antibody

APPL2 Reactivité: Humain ELISA, IHC, WB Hôte: Lapin Polyclonal
N° du produit ABIN5623056
$431.00
Plus shipping costs $45.00
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 9 à 11 jours ouvrables
N° du produit ABIN5535840
$550.00
Plus shipping costs $45.00
400 μL
local_shipping Destination: Etats-Unis
Envoi sous 2 à 3 jours ouvrables
N° du produit ABIN5516603
$229.00
Plus shipping costs $45.00
100 μL
local_shipping Destination: Etats-Unis
Envoi sous 2 à 3 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) anticorps Primary Antibody

APPL2 Reactivité: Humain, Souris, Rat ELISA, WB Hôte: Lapin Polyclonal
N° du produit ABIN5702507
$380.00
Plus shipping costs $45.00
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 13 à 16 jours ouvrables

anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) (PH domain) anticorps Primary Antibody

APPL2 Reactivité: Humain IP, IHC, ELISA, WB Hôte: Lapin Polyclonal
N° du produit ABIN2203417
$518.57
Plus shipping costs $45.00
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 à 16 jours ouvrables
N° du produit ABIN2203418
$625.43
Plus shipping costs $45.00
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 à 16 jours ouvrables
N° du produit ABIN2203419
$625.43
Plus shipping costs $45.00
50 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 à 16 jours ouvrables
N° du produit ABIN2203424
$658.43
Plus shipping costs $45.00
200 μL
local_shipping Destination: Etats-Unis
Envoi sous 11 à 16 jours ouvrables
N° du produit ABIN2203416
$658.43
Plus shipping costs $45.00
100 μL
local_shipping Destination: Etats-Unis
Envoi sous 11 à 16 jours ouvrables
N° du produit ABIN2203420
$814.00
Plus shipping costs $45.00
200 μL
local_shipping Destination: Etats-Unis
Envoi sous 16 jours ouvrables
N° du produit ABIN2203422
$814.00
Plus shipping costs $45.00
200 μL
local_shipping Destination: Etats-Unis
Envoi sous 16 jours ouvrables
N° du produit ABIN2203425
$814.00
Plus shipping costs $45.00
200 μL
local_shipping Destination: Etats-Unis
Envoi sous 16 jours ouvrables
N° du produit ABIN2203423
$814.00
Plus shipping costs $45.00
200 μL
local_shipping Destination: Etats-Unis
Envoi sous 16 jours ouvrables
  • Type Primary
    • Primary
  • Target Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2)
    • Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • tau Protein
    • CD4 Molecule (CD4)
    • Tumor Necrosis Factor alpha (TNF)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Estrogen Receptor 1 (ESR1)
    • Nuclear Factor-KB P65 (NFkBP65)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • Interferon gamma (IFNG)
    • Albumin (ALB)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • Heat Shock Protein 70 (HSP70)
    • Amyloid beta (A4) Precursor Protein (APP)
    • CD44
    • Tuberous Sclerosis 2 (TSC2)
    • Myc Proto-Oncogene protein (MYC)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • CD19 Molecule (CD19)
    • Histone H4
    • CD8a Molecule (CD8A)
    • Synuclein, alpha (SNCA)
    • Hemagglutinin (HA)
    • Integrin alpha M (ITGAM)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Jun Proto-Oncogene (JUN)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • CD8
    • Interleukin 6 (IL6)
    • Vimentin (VIM)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • CD5 Molecule (CD5)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Heat Shock 27kDa Protein 1 (HSPB1)
    • Mucin 1, Cell Surface Associated (MUC1)
    • CD3
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Interleukin 2 (IL2)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • CD14
    • CD34
    • Cyclin-Dependent Kinase 1 (CDK1)
  • Application
    • Western Blotting (WB)
    • ELISA
    • Immunofluorescence (IF)
    • Immunohistochemistry (IHC)
    • Immunoprecipitation (IP)
  • Réactivité
    • Humain
    • Souris
    • Rat
  • Cité dans publications
  • Images disponible
  • Hote
    • Lapin
    • Souris
  • Clonalité
    • Polyclonal
    • Monoclonal
  • Clone
    • 1C10
  • Epitope
    • AA 124-152
    • N-Term
    • AA 122-152
    • PH domain
    • AA 1-664
    • AA 174-274
    • AA 174-273
    • AA 619-662
    • C-Term
  • Conjugué
    • Inconjugué
    • APC
    • Alkaline Phosphatase (AP)
    • Biotin
    • FITC
    • HRP
    • PE
  • Isotype
    • IgG
    • IgG2b kappa
    • Ig Fraction
    • IgG2b
    • kappa
  • Format
    • Liquid

Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2) profil antigène

Profil protéine

The protein encoded by this gene is one of two effectors of the small GTPase RAB5A/Rab5, which are involved in a signal transduction pathway. Both effectors contain an N-terminal Bin/Amphiphysin/Rvs (BAR) domain, a central pleckstrin homology (PH) domain, and a C-terminal phosphotyrosine binding (PTB) domain, and they bind the Rab5 through the BAR domain. They are associated with endosomal membranes and can be translocated to the nucleus in response to the EGF stimulus. They interact with the NuRD/MeCP1 complex (nucleosome remodeling and deacetylase /methyl-CpG-binding protein 1 complex) and are required for efficient cell proliferation. A chromosomal aberration t(12\;22)(q24.1\;q13.3) involving this gene and the PSAP2 gene results in 22q13.3 deletion syndrome, also known as Phelan-McDermid syndrome.

Gene names and symbols associated with APPL2

  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (Appl2) anticorps
  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (APPL2) anticorps
  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 L homeolog (appl2.L) anticorps
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (appl2) anticorps
  • adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (appl2) anticorps
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (Appl2) anticorps
  • APPL2 anticorps
  • Dip3b anticorps
  • DIP13B anticorps
  • MGC84621 anticorps
  • RGD1563028 anticorps

Protein level used designations for APPL2

DCC-interacting protein 13-beta , adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 , amyloid beta (A4) precursor-like protein 2 , DIP13 beta , adapter protein containing PH domain, PTB domain and leucine zipper motif 2 , Dip3 beta , dip13-beta

GENE ID SPECIES
362860 Rattus norvegicus
418075 Gallus gallus
447596 Xenopus laevis
515605 Bos taurus
100000135 Danio rerio
100127202 Xenopus (Silurana) tropicalis
100545199 Meleagris gallopavo
100563730 Anolis carolinensis
100604575 Nomascus leucogenys
55198 Homo sapiens
216190 Mus musculus
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