anti-Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) Anticorps

AP3B1 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. De plus, nous expédions AP3B1 Protéines (3) et AP3B1 Kits (1) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
AP3B1 8546 O00203
AP3B1 11774 Q9Z1T1
AP3B1 309969  
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Top anti-AP3B1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 40 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-Ap3b1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Rat Liver 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of COLO 320 cells, using AP3B1 antibody. ABIN6272936 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué WB 100 μL 11 to 14 Days
$537.17
Détails
Humain Chèvre Inconjugué ELISA, FACS ABIN6391367 Flow cytometric analysis of paraformaldehyde fixed HepG2 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) fo 100 μg 6 to 7 Days
$429.84
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cell lines, using AP3B1 antibody. 200 μL 12 to 14 Days
$438.90
Détails
Humain Lapin Inconjugué WB Hepg2 lysates probed with HPS2 Polyclonal Antibody, Unconjugated  at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C. 100 μL 3 to 7 Days
$317.90
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of various cells, using AP3B1 antibody. 100 μL 11 to 13 Days
$366.77
Détails
Humain Souris Inconjugué ELISA, WB Detection limit for recombinant GST tagged AP3B1 is approximately 0.3ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg 11 to 12 Days
$440.00
Détails
Humain Souris Inconjugué ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL 11 to 12 Days
$305.71
Détails
Humain Souris Inconjugué WB Western Blot analysis of AP3B1 expression in transfected 293T cell line by AP3B1 MaxPab polyclonal antibody.Lane 1: AP3B1 transfected lysate(120.34 KDa).Lane 2: Non-transfected lysate. AP3B1 MaxPab polyclonal antibody. Western Blot analysis of AP3B1 expression in human placenta. 50 μg 11 to 12 Days
$440.00
Détails

anti-AP3B1 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal AP3B1 Primary Antibody pour WB - ABIN2778057 : Kuwahara, Inoue, DAgati, Fujimoto, Eguchi, Saha, Wolozin, Iwatsubo, Abeliovich: LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts. dans Scientific reports 2016 (PubMed)

Plus d’anticorps contre AP3B1 partenaires d’interaction

Human Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) interaction partners

  1. point mutation c.2702C>G in exon 23 of the AP3B1 gene caused deletion of 112 bp in the mRNA in two siblings. This mutation activates a cryptic donor splice site that overrules the wild-type donor splice site of this exon. Three other novel mutations in AP3B1 were identified, that is, a nonsense mutation c.716G>A (p.Trp239Ter), a 1-bp and a 4-bp deletion c.177delA and c.1839_1842delTAGA, respectively

  2. Synergistic defects of UNC13D and AP3B1 leading to adult hemophagocytic lymphohistiocytosis.

  3. Using a co-affinity purification strategy, authors have identified the beta subunit of the AP-3 adapter protein complex, AP3B1, as a binding partner for the M proteins of the zoonotic paramyxoviruses Nipah virus and Hendra virus.

  4. Data indicate that RUN and FYVE domain protein Rabip4'(RUFY1) interacts specifically and directly with adaptor protein complex AP-3.

  5. The study provides a description of two unrelated individuals with Hermansky Pudlak syndrome type 2 associated with novel mutations in AP3B1.

  6. diphosphoinositol pentakisphosphate-mediated pyrophosphorylation of AP3B1 modulates the interaction with Kif3A and, as a consequence, affects the release of HIV-1 virus-like particles.

  7. Two nonsense mutations in ADTB3A, C1578T (R-->X) and G2028T (E-->X), result in lack of ADTB3A mRNA and beta3A protein production and a severe, G-CSF-responsive neutropenia in addition to oculocutaneous albinism and platelet storage pool deficiency.

  8. Description of mutations in HPS genes that cause Hermansky-Pudlak syndrome (review)

  9. We defined a homozygous genomic deletion in AP3B1, the gene encoding the beta chain of the adaptor protein-3 (AP-3) complex. The mutation leads to in-frame skipping of exon 15 and thus perturbs proper assembly of the heterotetrameric AP-3 complex.

  10. A novel homozygous mutation in AP3B1 was detected in a 2-year-old patient with oculocutaneous albinism and immunodeficiency with Hermansky-Pudlak syndrome type II and eventual acute fatal hemophagocytic lymphohistiocytosis.

  11. Mutations in AP3B1 is not associated with familial hemophagocytic lymphohistiocytosis

  12. AP-1 and AP-3 are involved in the formation of distinct types of clathrin-coated vesicles, each of which is characterized by the incorporation of specific cargo membrane proteins

  13. Experimental investigation of five specific genes, AP3B1, ATP6AP1, BLOC1S1, LAMP2, and RAB11A, has confirmed novel roles for these proteins in the proper initiation of macroautophagy in amino acid-starved fibroblasts.

Mouse (Murine) Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1) interaction partners

  1. eye-specific segregation in the dLGN and topographic refinement of ipsilateral axons in the SC and the dLGN, are impaired in RIM1/2 conditional knock-out (Rim-cDKO) mice

  2. HIV-2 particle release was dependent on the adaptor protein complex AP-3 and the newly identified AP-5 complex, but much less so on AP-1.

  3. Data show that cytokine activation as a result of toll-like receptor 2 (TLR2) stimulation occurs at different intracellular locations and is mediated by the phagosomal trafficking molecule adaptor protein-3 (AP-3).

  4. has a minimal impact on protective anti-cytomegalovirus responses

  5. Our study indicates that Ap3b1 gene play distinct roles in melanin production and tyrosinase distribution compared with Hps1 gene.

  6. we show that loss of the related adaptor protein AP-1 has a similar effect on regulated secretion but exacerbates the effect of AP-3 RNAi, suggesting distinct roles for the two adaptors in the regulated secretory pathway.

  7. Data suggest functional links between OCA2 and the BLOC-1, BLOC-2, and AP-3 protein complexes involved in melanosome biogenesis.

  8. The identification of the feeble mutation led to our subsequent observations that AP-3, as well as the BLOC-1 and BLOC-2 are essential for plasmacytoid dendritic cells signaling through TLR7 and TLR9.

  9. TLR9 signals leading to activation of IFN I, require TLR9 trafficking from endosomes to lysosome-related organelle; adapter protein-3 identified as protein complex responsible for trafficking of TLR9 to this subcellular compartment

  10. AP-3 mediates the intracellular trafficking of CD1d to lysosomes for sampling of lipid antigens (Ags) involved in self-Ag presentation and thymocyte-positive selection.

  11. AP-3 requirement is a particular attribute of the CD1d pathway in mice and that, although MHC class II molecules and CD1d are both found in late endosomes or lysosomes, different pathways mediate their intracellular trafficking

  12. AP-3B plays a critical role in the normal formation and function of a subset of synaptic vesicles

  13. the functions of beta3A- and beta3B-containing complexes are distinct and divergent in brain

  14. AP-1 and AP-3 are involved in the formation of distinct types of clathrin-coated vesicles, each of which is characterized by the incorporation of specific cargo membrane proteins

  15. WNK4 inhibits NCC activity by diverting the cotransporter to the lysosome for degradation by way of an AP-3 transport carrier

AP3B1 profil antigène

Profil protéine

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with AP3B1

  • adaptor related protein complex 3 beta 1 subunit L homeolog (ap3b1.L) anticorps
  • adaptor-related protein complex 3, beta 1 subunit a (ap3b1a) anticorps
  • adaptor related protein complex 3 beta 1 subunit (AP3B1) anticorps
  • adaptor-related protein complex 3, beta 1 subunit (Ap3b1) anticorps
  • ADTB3 anticorps
  • ADTB3A anticorps
  • AP-3 anticorps
  • AP3B1 anticorps
  • AU015684 anticorps
  • beta3A anticorps
  • C78395 anticorps
  • cb964 anticorps
  • HPS anticorps
  • Hps2 anticorps
  • pe anticorps
  • pearl anticorps
  • rim2 anticorps

Protein level used designations for AP3B1

adaptor-related protein complex 3, beta 1 subunit , AP-3 complex subunit beta-1 , adaptor-related protein complex 3, beta-1 subunit , AP-3 complex subunit beta-1-like , AP-3 complex beta-3A subunit , adaptor protein complex AP-3 subunit beta-1 , beta-3A-adaptin , clathrin assembly protein complex 3 beta-1 large chain , adapter-related protein complex 3 subunit beta-1 , adaptor protein complex AP-3 beta-1 subunit , adaptor-related protein complex AP-3, beta 1 subunit , beta3A-adaptin , recombination induced mutation 2 , adaptor-related protein complex AP3 beta 1 subunit

GENE ID SPECIES
443724 Xenopus laevis
386770 Danio rerio
427646 Gallus gallus
461789 Pan troglodytes
100019944 Monodelphis domestica
100049670 Sus scrofa
100065436 Equus caballus
100226392 Taeniopygia guttata
100350054 Oryctolagus cuniculus
100397094 Callithrix jacchus
100584809 Nomascus leucogenys
708754 Macaca mulatta
8546 Homo sapiens
11774 Mus musculus
309969 Rattus norvegicus
767602 Bos taurus
403459 Canis lupus familiaris
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