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This locus encodes an inhibitor of the Wnt signaling pathway.
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Thus, we have provided the first evidence that APCDD1 expression is epigenetically silenced in OS, which may facilitate invasion and metastasis of OS cells.
these novel findings suggest that APCDD1 positively regulates adipogenic differentiation and that its down-regulation by miR (Montrer MLXIP Kits ELISA)-130 during diet-induced obesity may contribute to impaired adipogenic differentiation and obesity-related metabolic disease.
This study demonstrated a critical role for Apcdd1 in OL differentiation after white matter injury that points to a potential therapeutic approach for inhibiting Wnt (Montrer WNT2 Kits ELISA) signaling in these disorders.
Unusual role of APCDD1 in dental follicle cells during osteogenic differentiation. APCDD1 sustains the expression and activation of beta-catenin (Montrer CTNNB1 Kits ELISA).
mutation in the APCDD1 gene is responsible for hereditary hypotrichosis simplex in a large Chinese family.
Data show that the methylated VAPA (Montrer VAPA Kits ELISA)-APCDD1 DNA in maternal plasma is predominantly derived from the fetus, and this novel fetal epigenetic marker in maternal plasma is useful for the noninvasive detection of fetal trisomy 18.
APCDD1 is a novel inhibitor of the Wnt (Montrer WNT2 Kits ELISA) signalling pathway with an essential role in human hair growth
Suggest that APCDD1 modulates the gene expression of Wnt (Montrer WNT2 Kits ELISA)- and EK-related signaling molecules at the cap stage of tooth development, and is involved in tooth cusp patterning by modulating epithelial rearrangement.
mouse Drapc1 is a novel in vivo target gene of Wnt (Montrer WNT2 Kits ELISA)/beta-catenin (Montrer CTNNB1 Kits ELISA) signaling pathway
This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.
Adenomatosis polyposis coli down-regulated 1 protein homolog
, protein APCDD1
, adenomatosis polyposis coli down-regulated 1
, protein APCDD1-like
, APCDD1 homologue
, adenomatosis polyposis coli down-regulated 1 protein homolog
, protein primglo1
, adenomatosis polyposis coli down-regulated 1 protein
, hypoptrichosis simplex
, ethanol induced gene product EIG180
, Protein primglo