Adenosine Monophosphate Deaminase 2 Protéines (AMPD2)

The protein encoded by AMPD2 is important in purine metabolism by converting AMP to IMP. De plus, nous expédions AMPD2 Anticorps (57) et AMPD2 Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
AMPD2 271 Q01433
AMPD2 109674 Q9DBT5
Rat AMPD2 AMPD2 362015 Q02356
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Showing 5 out of 7 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Détails
Escherichia coli (E. coli) Humain His tag 100 μg 13 to 16 Days
$1,107.69
Détails
Wheat germ Humain GST tag 10 μg 11 to 12 Days
$340.00
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Détails

AMPD2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, ,
Mouse (Murine)

Plus protéines pour Adenosine Monophosphate Deaminase 2 (AMPD2) partenaires d'interaction

Human Adenosine Monophosphate Deaminase 2 (AMPD2) interaction partners

  1. These data demonstrate a novel mechanism in Systemic lupus erythematosus development that involves the targeting of AMPD2 expression by NovelmiRNA-25.

  2. Data suggest that adenosine monophosphate deaminase 2 (AMPD2) may serve as a biomarker for outcome prediction in undifferentiated pleomorphic sarcoma (UPS).

  3. The existence of various AMPD2 isoforms with different functions possibly explains the variability in phenotypes associated with AMPD2 variants: variants leaving some of the isoforms intact may cause spastic paraplegia type 63 , while those affecting all isoforms may result in the severe and early-onset Pontocerebellar hypoplasia type 9.

  4. Here we report the clinical and genetic analysis of an individual with PCH9 secondary to a novel missense variant with strong evidence of pathogenicity, located outside the catalytic domain of AMPD2

  5. tofacitinib increases the cellular levels of adenosine, which is known to have anti-inflammatory activity, through the downregulation of AMPD2. This would be a novel functional aspect of tofacitinib.

  6. In human HepG2 cells, AMPD2 activation counterregulates AMPK and increases intracellular glucose production, in association with up-regulation of PEPCK and G6Pc.

  7. Study concluded that AMPD2 as necessary for guanine nucleotide biosynthesis and protein translation and provide evidence that AMP deaminase activity is critical during neurogenesis. Patients with mutations in AMPD2 have characteristic brain imaging features of pontocerebellar hypoplasia due to loss of brainstem and cerebellar parenchyma.

  8. N-terminal extensions of the AMPD2 polypeptide influence ATP regulation of isoform L.

  9. This is a first report evidencing the pattern of AMPD genes expression in neoplastic human liver.

Mouse (Murine) Adenosine Monophosphate Deaminase 2 (AMPD2) interaction partners

  1. A novel mouse model of transient hypercholesterolemia with concurrent nephrotic syndrome associated with defective Ampd2 function.

  2. In diabetic mice, AMPD2 activation counterregulates AMPK and increases hepatic glucose production, in association with up-regulation of PEPCK and G6Pc.

Profil protéine AMPD2

Profil protéine

The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with AMPD2

  • adenosine monophosphate deaminase 2 (AMPD2)
  • adenosine monophosphate deaminase 2 (ampd2)
  • adenosine monophosphate deaminase 2 (Ampd2)
  • 1200014F01Rik Protéine
  • AI552571 Protéine
  • Ampd Protéine
  • Ampd-2 Protéine

Protein level used designations for AMPD2

adenosine monophosphate deaminase 2 , AMP deaminase 2-like , AMP deaminase 2 , AMPD , adenosine monophosphate deaminase 2 (isoform L)

GENE ID SPECIES
100033068 Monodelphis domestica
100061723 Equus caballus
100466659 Ailuropoda melanoleuca
100563338 Anolis carolinensis
100584841 Nomascus leucogenys
271 Homo sapiens
109674 Mus musculus
362015 Rattus norvegicus
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