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This protein belongs to the aldehyde dehydrogenases family of proteins.
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Human Polyclonal ALDH1B1 Primary Antibody pour ELISA, WB - ABIN4279201
Husemoen, Fenger, Friedrich, Tolstrup, Beenfeldt Fredriksen, Linneberg: The association of ADH and ALDH gene variants with alcohol drinking habits and cardiovascular disease risk factors. dans Alcoholism, clinical and experimental research 2008
These results suggest that ALDH1B1 is a novel human colorectal cancer biomarker
The aims of this study were: (i) to use bioinformatic techniques to characterize the possible effects of selected variants in ALDH1B1 on protein structure and function; and, (ii) to genotype three missense and one stop-gain, protein-altering, non-synonymous single nucleotide polymorphisms in 1478 alcohol dependent cases and 1254 controls of matched British and Irish ancestry.
ALDH1B1 is expressed at very high levels in human pancreatic cancer, and it contributes to proliferation in these tumor cells.
High expression of ALDH1A2 (Montrer ALDH1A2 Anticorps) and ALDH1B1 mRNA was found to be significantly correlated to worser survival in all NSCLC patients.
Data show that ALDH1B1 may promote colon cancer tumorigenesis by modulating the Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps), Notch (Montrer NOTCH1 Anticorps) and PI3K (Montrer PIK3CA Anticorps)/Akt (Montrer AKT1 Anticorps) signaling pathways.
ALDH1B1 metabolizes nitroglycerin and all-trans-retinaldehyde. One of the three human polymorphisms, ALDH1B1*2, is catalytically inactive, likely due to poor NAD(+) binding.
Our findings provide clear evidence for both individual and interactive associations of ALDH1b1 and ALDH2 genes with the development of coronary artery disease in Han Chinese.
ALDH1B1 SNPs play a role in shaping the alcohol drinking patterns among the Inuit in Greenland.
ALDH1 (Montrer ALDH1A1 Anticorps) is indicative of stemness and is a biomarker marker in colon cancer.
Telomere lengths in 52 distinct iodine-unstained lesions with reference to both their size and multiplicity, ALDH2 (Montrer ALDH2 Anticorps) and ADH1B (Montrer ADH1B Anticorps) genotypes, and smoking history, were investigated.
Aldehyde dehydrogenase has a critical role for beta cell development and functionality in mice
show for the first time the functional in vivo role of ALDH1B1 in acetaldehyde metabolism and in maintaining glucose homeostasis
ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.
ALDH class 2
, acetaldehyde dehydrogenase 5
, aldehyde dehydrogenase 5
, aldehyde dehydrogenase X, mitochondrial
, aldehyde dehydrogenase 5, mitochondrial X
, aldehyde dehydrogenase family 1 member B1
, aldehyde dehydrogenase 1 family, member B1
, aldehyde dehydrogenase X, mitochondrial-like
, cytosolic aldehyde dehydrogenase RF2D
, aldehyde dehydrogenase 1B1
, aldehyde dehydrogenase 3B1
, LOW QUALITY PROTEIN: aldehyde dehydrogenase X, mitochondrial