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ACCN4 belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. De plus, nous expédions Amiloride-Sensitive Cation Channel 4, Pituitary Anticorps (55) et Amiloride-Sensitive Cation Channel 4, Pituitary Protéines (6) et beaucoup plus de produits pour cette protéine.
Acid-sensing ion channel (ASIC (Montrer ACCN2 Kits ELISA)) 4 predominantly localizes to an early endosome-related organelle upon heterologous expression
Data show that transfected ASIC4 is targeted to the plasma membrane in CHO (Montrer COL11A1 Kits ELISA)-K1 cells, where it associates with ASIC1a (Montrer ACCN2 Kits ELISA) and downregulates exogenous ASIC1a (Montrer ACCN2 Kits ELISA) expression.
This study demonstrated that ASIC4 may modulate fear and anxiety by counteracting ASIC1a (Montrer ACCN2 Kits ELISA) activity in the brain.
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.
amiloride-sensitive cation channel 4, pituitary
, amiloride-sensitive cation channel 4, pituitary, isoform 1
, amiloride-sensitive cation channel 4-like
, acid-sensing ion channel 4
, amiloride-sensitive cation channel family member 4, pituitary
, brain sodium channel 4
, putative acid-sensing ion channel
, spinal chord ASIC