anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) Anticorps

The protein encoded by APBA3 is a member of the APBB protein family. De plus, nous expédions Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
APBA3 57267 O88888
APBA3 9546 O96018
APBA3 83611 O70248
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Top anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 55 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Chien Lapin Inconjugué WB WB Suggested Anti-APBA3 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from HuvEc cells, using APBA3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Chien Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, WB ABIN6274839 staining HuvEc by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. Western blot analysis of extracts from HUVEC cells, using APBA3 antibody.The lane on the left is treated with the antigen-specific peptide. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué WB APBA3 Antibody (Center)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the APBA3 antibody detected the APBA3 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Souris Lapin Inconjugué WB Figure 1 illustrates Western blot detection of Mint3 from AtT20 cell extract using ABIN267155. Western Blot: APBA3/Mint-3 Antibody [ABIN267155] - Analysis of Mint3 from AtT20 cell extract. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails
Souris Lapin Inconjugué IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. Lane 1: mouse spleen lysates Lane 2: mouse brain lysates probed with Anti APBA3/Mint3/X11 gamma Polyclonal Antibody, Unconjugated (ABIN1385696) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 63kD. Observed band size: 63kD. 100 μL Connectez-vous pour afficher 3 to 7 Days
$306.90
Détails
Humain Lapin Inconjugué WB Western blot analysis in NCI-H292 cell line lysates (35ug/lane). 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué ELISA, IHC, WB   100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails

Plus d’anticorps contre Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 partenaires d’interaction

Mouse (Murine) Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) interaction partners

  1. APBA3-deficient mice show reduced metastasis, with no apparent effect on primary tumor growth. APBA3 deficiency in inflammatory monocytes hampers glycolysis-dependent chemotaxis of cells toward metastatic sites.

  2. we have identified Mint3 as a physiological positive regulator of TLR3 (Montrer TLR3 Anticorps)/4 and RIG-I (Montrer DDX58 Anticorps)-induced IFN-beta (Montrer IFNB1 Anticorps) production and have outlined a feedback mechanism for the control of antiviral immune responses.

  3. Mint3 depletion attenuated metastasis to the lungs in breast cancer model mice.

  4. Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock.

  5. Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase (Montrer MMP16 Anticorps), MT5-MMP (Montrer MMP24 Anticorps), to the plasma membrane by binding to its carboxyl end motif EWV

  6. Binding of Munc18-1 (Montrer STXBP1 Anticorps) to closed, target-SNARE (Montrer VTI1B Anticorps) syntaxin 1 (Montrer STX1A Anticorps) stimulates vesicle docking and regulates the consecutive priming step during exocytosis of secretory or synaptic vesicles.

  7. X11L2 functions in the nucleus by a mechanism distinct from conventional transactivators

Human Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) interaction partners

  1. Results suggest that NECAB3 (Montrer NECAB3 Anticorps), a novel Mint3-binding protein, activates HIF-1 (Montrer HIF1A Anticorps) to promote normoxic glycolysis and tumorigenicity by forming a ternary complex with Mint3 and FIH-1 (Montrer HIF1AN Anticorps).

  2. FIH-1 (Montrer HIF1AN Anticorps)-Mint3 axis does not control HIF-1 (Montrer HIF1A Anticorps) transcriptional activity in nucleus pulposus cells.

  3. Mints are necessary for activity-induced APP (Montrer APP Anticorps) and PS1 (Montrer PSEN1 Anticorps) trafficking and provide insight into the cellular fate of APP (Montrer APP Anticorps) in endocytic pathways essential for Abeta (Montrer APP Anticorps) production.

  4. Strict specificity for recruitment of the Mint3 adaptor by APP (Montrer APP Anticorps) at the Golgi, a critical role for Tyr (Montrer TYR Anticorps)-682 (within the YENPTY motif) in Mint3 recruitment and export of APP (Montrer APP Anticorps) from the Golgi, are demonstrated.

  5. These results indicate that all three amyloid beta protein precursor family members are capable of activating gene transcription via Mint3-Taz (Montrer TAZ Anticorps) and Mint3-Yap (Montrer YAP1 Anticorps).

  6. Two transcriptional coactivators, TAZ (Montrer TAZ Anticorps) and YAP (Montrer YAP1 Anticorps), functionally associate with amyloid precursor protein (Montrer APP Anticorps) through Mint3 and form transcriptionally active triple protein complexes.

  7. Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase (Montrer MMP16 Anticorps), MT5-MMP (Montrer MMP24 Anticorps), to the plasma membrane by binding to its carboxyl end motif EWV

  8. We have examined the ability of Bcr (Montrer BCR Anticorps) to interact with other epithelial PDZ (Montrer INADL Anticorps) proteins and found specific binding to both the apical PDZK1 (Montrer PDZK1 Anticorps) protein and the Golgi-localized Mint3

  9. These data implicate Mint3 activity as a critical determinant of post-Golgi APP (Montrer APP Anticorps) traffic.

  10. the interaction between the PTB (Montrer PTBP1 Anticorps) domain of Mint3 and the acidic peptide signal of Furin (Montrer FURIN Anticorps) regulates the specific localization of Furin (Montrer FURIN Anticorps) in the trans-Golgi network

Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) profil antigène

Profil protéine

The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease.

Gene names and symbols associated with APBA3

  • amyloid beta precursor protein binding family A member 3 (APBA3) anticorps
  • amyloid beta (A4) precursor protein-binding, family A, member 3 (Apba3) anticorps
  • amyloid beta precursor protein binding family A member 3 (Apba3) anticorps
  • AW208791 anticorps
  • lin-10 anticorps
  • MGC:15815 anticorps
  • Mint-3 anticorps
  • Mint3 anticorps
  • X11gamma anticorps
  • X11L2 anticorps

Protein level used designations for APBA3

amyloid beta (A4) precursor protein-binding, family A, member 3 , Mint 3 , adapter protein X11gamma , amyloid beta A4 precursor protein-binding family A member 3 , neuron-specific X11L2 protein , neuronal munc18-1-interacting protein 3 , X11-like 2 protein , amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2) , mint-3 , phosphotyrosine-binding/-interacting domain (PTB)-bearing protein , amyloid beta (A4) precursor protein-binding family A member 3 (X11-like 2) , amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2) , neuronal Munc18-1-interacting protein 3

GENE ID SPECIES
100021747 Monodelphis domestica
57267 Mus musculus
9546 Homo sapiens
485053 Canis lupus familiaris
83611 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) Anticorps
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