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The protein encoded by AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. De plus, nous expédions AMOTL1 Anticorps (36) et et beaucoup plus de produits pour cette protéine.
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HECW2, a novel EC ubiquitin E3 ligase, plays a critical role in stabilizing endothelial cell-to-cell junctions by regulating AMOT (Montrer AMOT Kits ELISA)-like 1 (AMOTL1) stability.
AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin (Montrer NF2 Kits ELISA).
phosphorylation-deficient S793Ala mutant of AMOTL1 showed a shorter half-life and conferred resistance to energy-stress-induced YAP (Montrer YAP1 Kits ELISA) inhibition.
study defined eight additional recurrently mutated genes in SMZL; these genes are CREBBP, CBFA2T3, AMOTL1, FAT4, FBXO11, PLA2G4D, TRRAP and USH2A.
miR (Montrer MLXIP Kits ELISA)-124 binds AmotL1 3'UTR (Montrer UTS2R Kits ELISA) and down-regulates its expression repressing vasculogenic mimicry and cell motility in cervical cancer cells.
Scaffold proteins angiomotin (Amot (Montrer AMOT Kits ELISA)) and angiomotin (Montrer AMOT Kits ELISA)-related AmotL1 and AmotL2 (Montrer AMOTL2 Kits ELISA) were recently identified as negative regulators of YAP (Montrer YAP1 Kits ELISA) and TAZ (Montrer TAZ Kits ELISA) by preventing their nuclear translocation.
These results suggested that IFN-gamma exhibits anti-angiogenesis effects by regulating the expression of TNF-alpha-induced AmotL1 via NFkappaB in emphysema lungs.
AmotL1 and ZO-2 (Montrer TJP2 Kits ELISA) are two candidates that could be harnessed to control the oncogenic function of YAP (Montrer YAP1 Kits ELISA).
By yeast two-hybrid screening, angiomotin-like 1 (AmotL1) was identified as a host factor that interacts with the M protein (Montrer MYOM2 Kits ELISA) of parainfluenza virus 5 (PIV5).
The angiomotin-like 1 is involved in actin-cytoskeleton-based processes, in part, via its interaction with a p80-angiomotin-containing complex and the actin cytoskeleton
Amot (Montrer AMOT Kits ELISA) and AmotL1 have similar effects on endothelial migration and tight junction formation in vitro. In vivo Amot (Montrer AMOT Kits ELISA) appears to control the cell polarity and AmotL1 affects the stability of cell-cell junctions.
The authors propose that AmotL1 is an essential effector of the N-cadherin (Montrer CDH2 Kits ELISA) mediated endothelial/pericyte junctional complex.
Amot (Montrer AMOT Kits ELISA), Amotl1, and Amotl2 (Montrer AMOTL2 Kits ELISA) are differentially expressed in uterine cells during the peri (Montrer POSTN Kits ELISA)-implantation period.
Data show that MUPP1 interacts with angiomotin (Amot (Montrer AMOT Kits ELISA)), JEAP/Amot (Montrer AMOT Kits ELISA)-like 1 and MASCOT/Amot (Montrer AMOT Kits ELISA)-like 2, and that all the Amot (Montrer AMOT Kits ELISA)/JEAP family proteins also interacted with Patj, a close relative of MUPP1.
The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.
angiomotin like 1
, angiomotin-like protein 1-like
, angiomotin-like protein 1
, junction-enriched and associated protein
, junction-enriched and -associated protein