anti-Anillin, Actin Binding Protein (ANLN) Anticorps

Required for cytokinesis. De plus, nous expédions Anillin Kits (8) et Anillin Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ANLN 54443 Q9NQW6
ANLN 68743 Q8K298
ANLN 363031  
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Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Chèvre Inconjugué ELISA, FACS, IF, IHC ABIN185086 (10µg/ml) staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. ABIN185086 Immunofluorescence analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing nuclear staining. Actin filaments were stained wit 100 μg 6 to 7 Days
Humain Chèvre Inconjugué ELISA, WB ABIN185662 (1µg/ml) staining of Mouse Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
Boeuf (Vache) Chèvre Inconjugué EIA, IHC (p), WB   0.1 mg 4 to 8 Days
Roussette (Chauve-souris) Chèvre Inconjugué ELISA, WB 100 μg 11 to 14 Days
Chien Chèvre Inconjugué WB   0.1 mg 4 to 8 Days
Humain Lapin Inconjugué IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded human placenta labeled with Anti-Anillin Polyclonal Antibody, Unconjugated (ABIN872314) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
Humain Lapin Inconjugué FACS, WB   100 μg 4 to 6 Days
Boeuf (Vache) Chèvre Inconjugué ELISA   100 μg 11 to 14 Days
Souris Chèvre Inconjugué IHC, ELISA 0.1 mg 2 to 3 Days
Humain Lapin Alexa Fluor 647 IF (p)   100 μL 14 to 21 Days

anti-Anillin Anticorps mieux référencés

  1. Human Polyclonal Anillin Primary Antibody pour ICC, IF - ABIN4280671 : Hjelm, Forsström, Igel, Johannesson, Stadler, Lundberg, Ponten, Sjöberg, Rockberg, Schwenk, Nilsson, Johansson, Uhlén: Generation of monospecific antibodies based on affinity capture of polyclonal antibodies. dans Protein science : a publication of the Protein Society 2011 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal Anillin Primary Antibody pour ICC, IF - ABIN441099 : Wang, Batourina, Schneider, Souza, Swayne, Liu, George, Tate, Dan, Wiessner, Zhuravlev, Canman, Mysorekar, Mendelsohn: Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and Endoreplication. dans Cell reports 2018 (PubMed)

  3. Dog (Canine) Polyclonal Anillin Primary Antibody pour ELISA, WB - ABIN547706 : Hall, Todd, Hyland, McDade, Grabsch, Dattani, Hillan, Russell: The septin-binding protein anillin is overexpressed in diverse human tumors. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2005 (PubMed)

  4. Human Polyclonal Anillin Primary Antibody pour ELISA - ABIN547152 : Oegema, Savoian, Mitchison, Field: Functional analysis of a human homologue of the Drosophila actin binding protein anillin suggests a role in cytokinesis. dans The Journal of cell biology 2000 (PubMed)

Plus d’anticorps contre Anillin partenaires d’interaction

Human Anillin, Actin Binding Protein (ANLN) interaction partners

  1. Missense mutation in ANLN was identified as a cause of branchio-otic syndrome in a specific Chinese family.

  2. Bladder urothelial carcinoma patients with elevated ANLN expression had poorer survival prospects.

  3. Knockdown of ANLN in liver cells blocks cytokinesis and inhibits development of liver tumors.

  4. Authors found that decreasing Ran-GTP levels or tethering active Ran to the equatorial membrane affects anillin's localization and causes cytokinesis phenotypes.

  5. Anillin (ANLN) expression in tumor cells is correlated to poor prognosis in breast cancer patients, independent of Ki-67 or tumor size.

  6. S635 phosphorylation is essential for cytokinesis.

  7. ANLN expression is elevated in colorectal cancer and has a strong potential to act as a biomarker for the prognosis of colorectal cancer.

  8. Findings indicate that miR-497 is a potent tumor suppressor that inhibits cancer phenotypes by targeting ANLN and HSPA4L in NPC.

  9. High nuclear expression of anillin (ANLN) is an independent predictor of poor disease-specific survival and it is a useful prognostic marker of urothelial carcinoma of the upper urinary tract (UCUT).

  10. Data suggest that anillin (ANLN) could be involved in breast cancer progression and a potential target candidate in breast cancer.

  11. Identification 4 novel and 18 known exonic ANLN variants associated with carotid intima-media thickness at bifurcation.

  12. Anillin regulates intercellular adhesion in model human epithelia by mechanisms involving the suppression of JNK activity and controlling the assembly of the perijunctional cytoskeleton.

  13. The sequestration of anillin by astral microtubules might alter the organization of cortical proteins to polarize cells for cytokinesis

  14. these data demonstrate that a complex of p190RhoGAP-A and anillin modulates RhoA-GTP levels in the cytokinetic furrow to ensure progression of cytokinesis.

  15. Identified a missense mutation R431C in anillin (ANLN), an F-actin binding cell cycle gene, as a cause of FSGS. We screened 250 additional families with FSGS and found another variant, G618C, that segregates with disease in a second family with FSGS.

  16. ANLN is positively associated with Wnt/beta-catenin signaling in gastric cancer.Elevated expression of ANLN is a predictor of intestinal type gastric cancer. ER-alpha is negatively associated with the expression of ANLN in gastric cancer.

  17. Supervillin concentrates activated and total myosin II at the furrow, and simultaneous knockdown of supervillin and anillin additively increases cell division failure.

  18. Antibody screening revealed 3 candidate prognostic markers in breast cancer: the Anillin (ANLN); PDZ-Binding Kinase (PBK); and, PDZ-Domain Containing 1 (PDZK1).

  19. Data supports an analogous function for the anillin-Ect2 complex in human cells and one hypothesis is that this complex has functionally replaced the Drosophila anillin-RacGAP50C complex.

  20. CIT-K is capable of physically and functionally interacting with the actin-binding protein anillin.

Mouse (Murine) Anillin, Actin Binding Protein (ANLN) interaction partners

  1. Anillin controls the levels of the GTPase RhoA, a known regulator of osteoclast cytoskeleton and resorption activity.

  2. Loss of ANLN expression is associated with tumorigenesis in liver.

  3. Knockdown of ANLN in liver cells blocks cytokinesis and inhibits development of liver tumors.

  4. data suggest that anillin is an essential intracellular component that maintains the integrity of asymmetric division in mouse oocytes.

  5. Anillin is excluded from the cortex of first polar body, enriched in the cytokinetic ring that severs the polar body from the oocyte. In meiosis II, anillin is enriched in a cortical stripe coincident with and overlying the meiotic spindle midzone.

  6. Results show that targeting of mDia2 to the cleavage furrow requires not only its binding to RhoA but also its diaphanous-inhibitory domain, and identify anillin as a novel mDia2 interaction partner.

Fruit Fly (Drosophila melanogaster) Anillin, Actin Binding Protein (ANLN) interaction partners

  1. we show that the transition from the actomyosin contractile ring to the midbody ring proceeds via a previously uncharacterized maturation process that requires opposing mechanisms of removal and retention of the scaffold protein Anillin.

  2. Anillin is required for complete closure of the contractile ring and formation of the midbody ring during cytokinesis.

  3. the anillin pleckstrin homology domain has two functions: targeting anillin to the plasma membrane furrow by binding to phosphatidylinositol phosphate lipids to maintain furrow organization and recruiting septins to the furrow.

  4. Data suggest that Cindr and Anillin cooperate to promote intercellular bridge stability during incomplete cytokinesis in Drosophila melanogaster.

  5. Results show that the anillin-septin and cadherin-catenin complexes can serve as alternative cassettes to promote tight physical coupling of F-actin and myosin II to the cleavage furrow and successful completion of cytokinesis.

  6. anillin has a role in spatially regulating the contractile activity of myosin II during cytokinesis

  7. important role for scraps in scaffolding cleavage furrow components, directly stabilizing intracellular bridges

  8. A novel RhoGEF(Pbl)-dependent input promotes the simultaneous association of anillin with the plasma membrane, septins, and microtubules, independently of F-actin.

  9. interaction with cleavage furrow mediates RacGAP50C's control of actomyosin ring assembly

  10. anillin and Peanut are involved in pseudocleavage furrow ingression in syncytial embryos, a process that is regulated by Ran

Xenopus laevis Anillin, Actin Binding Protein (ANLN) interaction partners

  1. The authors propose that anillin is required for proper Rho-GTP distribution at cell-cell junctions and for maintenance of a robust apical actomyosin belt, which is required for cell-cell junction integrity.

  2. anillin has a role in spatially regulating the contractile activity of myosin II during cytokinesis

Zebrafish Anillin, Actin Binding Protein (ANLN) interaction partners

  1. The study provides the in vivo evidence for the requirement of Anillin during asymmetric neurogenic divisions.

Anillin (ANLN) profil antigène

Profil protéine

Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression (By similarity).

Gene names and symbols associated with ANLN

  • anillin actin binding protein (ANLN) anticorps
  • anillin, actin binding protein (Anln) anticorps
  • anillin actin binding protein (anln) anticorps
  • scraps (scra) anticorps
  • anillin actin binding protein L homeolog (anln.L) anticorps
  • anillin, actin binding protein (anln) anticorps
  • 1110037A17Rik anticorps
  • 2900037I21Rik anticorps
  • Abp8 anticorps
  • ani anticorps
  • anil anticorps
  • anillin anticorps
  • ANLN anticorps
  • C78101 anticorps
  • CG2092 anticorps
  • Dmel\\CG2092 anticorps
  • l(2)03427 anticorps
  • l(2)43Ec anticorps
  • l(2)k08255 anticorps
  • RGD1561367 anticorps
  • Scra anticorps
  • scraps anticorps
  • si:ch211-197n10.2 anticorps
  • wu:fb74d05 anticorps
  • wu:fd10d09 anticorps
  • wu:fi41f04 anticorps

Protein level used designations for ANLN

actin-binding protein anillin , anillin, actin binding protein , anillin, actin binding protein (scraps homolog, Drosophila) , actin-binding protein anillin-like , Actin-binding protein 8 , CG2092-PA , CG2092-PB , CG2092-PC , anillin , annilin , lethal (2) k08255 , scra-PA , scra-PB , scra-PC , contractile ring component anillin

54443 Homo sapiens
420738 Gallus gallus
463351 Pan troglodytes
482401 Canis lupus familiaris
518274 Bos taurus
706404 Macaca mulatta
100351074 Oryctolagus cuniculus
100387382 Callithrix jacchus
100469164 Ailuropoda melanoleuca
68743 Mus musculus
100329114 Xenopus (Silurana) tropicalis
100548396 Meleagris gallopavo
100558878 Anolis carolinensis
100581939 Nomascus leucogenys
35696 Drosophila melanogaster
398569 Xenopus laevis
100523340 Sus scrofa
363031 Rattus norvegicus
101116045 Ovis aries musimon
562517 Danio rerio
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