Profil protéine

This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with ASB2

• ankyrin repeat and SOCS box containing 2 (ASB2) anticorps
• ankyrin repeat and SOCS box-containing 2 (Asb2) anticorps
• ankyrin repeat and SOCS box containing 2 (Asb2) anticorps
• ankyrin repeat and SOCS box containing 2b (asb2b) anticorps

• 1110008E15Rik anticorps
• ASB-2 anticorps
• asb2 anticorps
• zgc:77223 anticorps

Protein level used designations for ASB2

ankyrin repeat and SOCS box protein 2 , ankyrin repeat and SOCS box-containing protein 2a , ASB-2 , ankyrin repeat and SOCS box-containing protein 2 , ankyrin repeat-containing SOCS box protein 2 , ankyrin repeat and SOCS box-containing 2 , ankyrin repeat and SOCS box protein 2-like