Anoctamin 1, Calcium Activated Chloride Channel (ANO1) Kits ELISA

Acts as a calcium-activated chloride channel. De plus, nous expédions ANO1 Anticorps (357) et ANO1 Protéines (8) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
ANO1 55107 Q5XXA6
Anti-Souris ANO1 ANO1 101772 Q8BHY3
Anti-Rat ANO1 ANO1 309135  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top ANO1 Kits ELISA sur anticorps-enligne.fr

Showing 2 out of 2 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$830.12
Détails
Cobaye
  96 Tests 16 to 21 Days
$1,161.29
Détails

Plus Kits ELISA pour ANO1 partenaires d'interaction

Guinea Pig Anoctamin 1, Calcium Activated Chloride Channel (ANO1) interaction partners

  1. Downregulation of TMEM16A may be associated with ageassociated hearing loss.

  2. Antigen challenge and Calcium-dependent agonist treatment increased Chloride ion transport via the overexpression of TMEM16A in goblet cell metaplasia in a guinea-pig asthma model

  3. These findings demonstrate that multiple members of this recently described family of CaCCs are expressed in HASM cells, they display classic electrophysiological properties of CaCCs, and they modulate contractile tone in airway smooth muscle.

Human Anoctamin 1, Calcium Activated Chloride Channel (ANO1) interaction partners

  1. miR-9 inhibits colorectal cancer cell proliferation, migration, and invasion by directly targeting.

  2. These findings provide mechanistic insight into promoting apoptosis in prostate cancer cells by ANO1 inhibition through upregulation of TNF-alpha signaling.

  3. ANO1 overexpression is involved in the pathogenesis of human epithelial ovarian cancer. Inhibition of ANO1 upregulation or inactivating PI3K/Akt signaling may have therapeutic potential for epithelial ovarian cancer, and the detection of ANO1 expression level in peripheral blood mononuclear cells from patients may also serve as a biomarker for diagnosis and prognosis of epithelial ovarian cancers.

  4. Discovered on GIST1 (DOG1) is expressed in the extraintestinal gastrointestinal stromal tumors just as well as it is in intestinal gastrointestinal stromal tumors (GISTs) and it may be more adept at diagnosing GISTs with an epithelioid morphology.

  5. TMEM16A is shown to be essential for proper activation and membrane expression of CFTR.

  6. These results are the first to show the contribution of positively correlated CpG's for regulating gene expression in head and neck squamous cell carcinoma. Hypermethylation of the ANO1 promoter was strongly correlated with but not sufficient to increase ANO1 expression, suggesting methylation of positively correlated CpG's likely serves as an adjunct to other mechanisms of ANO1 activation.

  7. Study demonstrated that miR144 was downregulated and anoctamin 1 (ANO1) expression was upregulated in colorectal cancer (CRC). The expression of ANO1 was negatively associated with that of miR144 in CRC. The present study indicated that upregulated expression of ANO1 was associated with poor differentiation and advanced tumornodemetastasis stage.

  8. in airway epithelial cells, stimulation of purinergic or muscarinic G-protein coupled receptors (GPCRs) activates TMEM16A and CFTR.

  9. Study demonstrates that anoctamin 1 is the only anoctomin mRNA isoform differentially expressed between pregnant (late gestation, nonlaboring) and nonpregnant myometrium.

  10. Bile acids stimulate Cl(-) secretion in biliary cells through activation of membrane TMEM16A channels in a process regulated by extracellular ATP and [Ca(2+) ]i .

  11. This will include discussion of developed knockout models that have provided much needed insight on the functional localization of TMEM16A in several epithelial tissues. Finally, this review will examine the implications of the identification of TMEM16A as it pertains to potential novel therapies in several pathologies

  12. Inhibition of STAT6/Anoctamin-1 activation decreased proliferation, migration, or invasion of gastric cancer cells.

  13. The effect of CLCA2 on ICaCC (calcium-activated chloride channel currents) was tested in HEK293 cells stably expressing calcium-activated chloride channel TMEM16A.

  14. TMEM16A expression was found to correlate with greater tumor size, less Bim expression, and less apoptotic activity overall in head and neck squamous cell carcinomas (HNSCCs).

  15. resveratrol (RES) might be a promising drug for the treatment of gastrointestinal hypomotility. As RES was able to induce TMEM16A channel activation, TMEM16A can be added to the list of RES drug targets.

  16. results indicate that the enhanced activity in chimeric channels is due to altered interaction between the carboxy-terminus and the first intracellular loop in the TMEM16A homo-dimer. Mimicking this perturbation with a small molecule could be the basis for a pharmacological stimulation of TMEM16A-dependent Cl(-) transport.

  17. ANO1 overexpression associated with the high expression of EGFR can be a predictive marker of recurrence after surgery in non-small cell lung cancer

  18. Study demonstrated that segment a is a critical domain for the surface expression of ANO1, and identified 14-3-3gamma as a binding partner for this segment enhancing the surface expression of ANO1. In addition, gene silencing of 14-3-3gamma and/or ANO1 inhibited migration and invasion of these glioblastoma cell lines.

  19. lipids and fatty acids regulate TMEM16A channels through a membrane-delimited protein-lipid interaction.

  20. knockdown of ESYT1 (and family members ESYT2 and ESYT3) significantly decreased ANO1 current density.

Mouse (Murine) Anoctamin 1, Calcium Activated Chloride Channel (ANO1) interaction partners

  1. suggest that miR-9 can indirectly activate the TGF-beta-Smad3 pathway by inhibiting the expression of ANO1

  2. Loss of TMEM16A resulted in reduced nephron number and, subsequently, albuminuria and tubular damage.

  3. https://kdvr.com/2013/06/19/she-gave-elvis-presley-his-first-on-screen-kiss-then-became-a-nun/

  4. ANO1 expression was unaffected by betaENaC overexpression in the Scnn1b-Tg line.

  5. A G protein-coupled receptor-TMEM16A-voltage-dependent Ca(2+) channel axis contributes to inflammatory mediator-induced airway smooth muscle contraction and synergistically activated TMEM16A by allergic inflammatory mediators with cholinergic stimuli in asthma.

  6. Voltage modulation of TMEM16A-calcium-activated chloride channel involves voltage-dependent occupancy of calcium- and anion-binding sites.

  7. TMEM16A is shown to be essential for proper activation and membrane expression of CFTR.

  8. Decreased expression of TMEM16A in DSS-induced colitis contributes to the decreased Ca(2+)-activated Cl(-) secretion in murine colon.

  9. Serine 727 phosphorylation in TMEM16A by CaMKIIgamma provides a new mechanism for regulating TMEM16A CaCC activity and Ang II-induced BASMC proliferation.

  10. The mAno1 expression is regulated via alternative promoters, and its transcriptional variation results in variation of the N-terminal sequence of the Ano1 protein due to the alternative translation initiation sites.

  11. we demonstrate the electrostatic control of permeation by the bound calcium ions in mouse TMEM16A using electrophysiology and Poisson-Boltzmann calculations..The currents of constitutively active mutants lose their outward rectification as a function of Ca(2+) concentration due to the alleviation of energy barriers for anion conduction

  12. Bile acids stimulate Cl(-) secretion in biliary cells through activation of membrane TMEM16A channels in a process regulated by extracellular ATP and [Ca(2+) ]i .

  13. TMEM16A modulates arterial contractility, at least in part, indirectly via regulation of CACNA1C expression.

  14. the glutamic acids (E) at 143 and 705 residues in ANO1 are critical for modulation of Ca2 and/or heat responses.

  15. anoctamin-1 is involved in psychiatric behavior because of its role in the regulation of synaptic transmission in presynaptic terminals

  16. de novo atomic structures of the transmembrane domains of mouse TMEM16A in nanodiscs and in lauryl maltose neopentyl glycol as determined by single-particle electron cryo-microscopy

  17. cryo-EM structures of mouse TMEM16A at high resolution in the presence and absence of Ca(2+)

  18. The protein shows a similar organization to nhTMEM16, except for changes at the site of catalysis. There, the conformation of transmembrane helices constituting a membrane-spanning furrow that provides a path for lipids in scramblases has changed to form an enclosed aqueous pore that is largely shielded from the membrane.

  19. ANO1 immunoreactivity was observed in the presynaptic terminals of various retinal neurons, including photoreceptors

  20. In this work we demonstrate that increasing the extracellular proton concentration from 10-10 to 10-5.5 m enabled TMEM16A activation. Furthermore, we show that this effect is voltage independent, caused by changes in the apparent open probability of the channel, and due to protonation of extracellular residue E623

ANO1 profil antigène

Antigen Summary

Acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity).

Gene names and symbols associated with ANO1

  • anoctamin 1 (Ano1) anticorps
  • anoctamin 1 (ANO1) anticorps
  • anoctamin 1, calcium activated chloride channel (Ano1) anticorps
  • DOG1 anticorps
  • ORAOV2 anticorps
  • TAOS2 anticorps
  • Tmem16a anticorps

Protein level used designations for ANO1

anoctamin 1, calcium activated chloride channel , Ca-activated chloride channel Tmem16A , anoctamin-1 , discovered on gastrointestinal stromal tumors protein 1 , oral cancer overexpressed 2 , transmembrane protein 16A (eight membrane-spanning domains) , tumor-amplified and overexpressed sequence 2 , transmembrane protein 16A

GENE ID SPECIES
100529098 Cavia porcellus
55107 Homo sapiens
423144 Gallus gallus
532126 Bos taurus
101772 Mus musculus
309135 Rattus norvegicus
611698 Canis lupus familiaris
Fournisseurs de qualité sélectionnés pour ANO1 (ANO1) Kits ELISA
Avez-vous cherché autre chose?