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The protein encoded by APOM is an apolipoprotein and member of the lipocalin protein family. De plus, nous expédions Apolipoprotein M Anticorps (177) et Apolipoprotein M Protéines (25) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 42 products:
Human Apolipoprotein M Kit ELISA pour Sandwich ELISA - ABIN417454
Huang, Liu, Jiang, Sun, Zhang, Liu, Xu: Apolipoprotein m (APOM) levels and APOM rs805297 G/T polymorphism are associated with increased risk of rheumatoid arthritis. dans Joint, bone, spine : revue du rhumatisme 2014
Show all 6 Pubmed References
Mouse (Murine) Apolipoprotein M Kit ELISA pour Sandwich ELISA - ABIN810844
Kurano, Tsukamoto, Hara, Ohkawa, Ikeda, Yatomi: LDL Receptor and ApoE are Involved in the Clearance of ApoM-associated Sphingosine 1-phosphate. dans The Journal of biological chemistry 2014
results demonstrated that lower APOM levels in SLE patients and correlated with disease activity.
Sequenced the ApoM gene in recurrent venous thromboembolism (VTE) and identified six polymorphisms. ApoM rs805297 was significantly associated with higher risk of VTE recurrence in male but not in female patients.
Single nucleotide polymorphism in ApoM gene is associated with chronic obstructive pulmonary disease.
ApoM T-855C and T-778C polymorphisms were found to be associated with obesity by regulating HDL (Montrer HSD11B1 Kits ELISA) metabolism, and the T alleles of apoM T-778C were shown to be more strongly correlated.
liver mRNA levels of apoM and apoA1 (Montrer APOA1 Kits ELISA) decreased strongly upon sepsis induction.
17beta-estradiol induced up-regulation of apoM in HepG2 cells is through an ER-alpha (Montrer ESR1 Kits ELISA)-dependent pathway involving ER-alpha (Montrer ESR1 Kits ELISA) binding element in the promoter of the apoM gene.
A shift in ApoM/sphingosine 1-phosphate between HDL-particles in women with type 1 diabetes mellitus Is associated with impaired anti-inflammatory effects of the ApoM/S1P complex.
ApoM-bound sphingosine-1-phosphate regulates adhesion molecule (Montrer NCAM1 Kits ELISA) abundance, leukocyte-endothelial adhesion, and endothelial barrier function via sphingosine-1-phosphate receptor1.
HDL (Montrer HSD11B1 Kits ELISA)-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 (Montrer S1PR1 Kits ELISA) and S1P3 (Montrer S1PR3 Kits ELISA) receptors on vascular endothelium.
Plasma apoM concentrations are higher in patients with hyperlipidaemia than in healthy controls. Low plasma apoM levels in patients with T2DM are likely caused by diabetes but are not induced by hyperlipidaemia.
This suggests that the autophagy dysfunction caused by the deficiency of ApoM is an important factor in hepatic steatosis (triglyceride accumulation). ApoM plays a key role in normal autophagy activity in the liver and thereby further regulates the metabolism of liver lipids, particularly triglycerides.
HDL facilitates S1P efflux from erythrocytes by both apoM-dependent and apoM-independent mechanisms. Moreover, apoM facilitates tubular reabsorption of S1P from the urine, however, with no impact on S1P plasma concentrations.
The study suggests that vascular leakage of albumin (Montrer ALB Kits ELISA)-sized particles in ApoM deficiency is S1P (Montrer S1PR1 Kits ELISA)- and S1P1 (Montrer S1PR1 Kits ELISA)-dependent and this dependency exacerbates the response to inflammatory stimuli.
apoM might facilitate the maintenance of CD4 (Montrer CD4 Kits ELISA)(+) T-lymphocytes or could modify the T-lymphocytes subgroups in murine spleen
Upon immune stimulation, Apom(-/-) mice developed more severe experimental autoimmune encephalomyelitis, characterized by increased lymphocytes in the central nervous system and breakdown of the blood-brain barrier
LDL receptor (Montrer LDLR Kits ELISA) and ApoE (Montrer APOE Kits ELISA) have roles in the clearance of ApoM-associated sphingosine 1-phosphate
ApoM augmented insulin secretion by maintaining the S1P concentration under both in vivo and in vitro conditions.
The present data indicate that the plasma apo-M levels modulate the ability of plasma to mobilize cellular cholesterol, whereas apo-M has no major effect on the excretion of cholesterol into feces.
ApoM can bind oxidized phospholipids, increasing the antioxidant effect of HDL (Montrer HSD11B1 Kits ELISA).
Results show that apoM, by delivering S1P (Montrer S1PR1 Kits ELISA) to the S1P (Montrer S1PR1 Kits ELISA)(1) receptor on endothelial cells, is a vasculoprotective constituent of HDL (Montrer APOA5 Kits ELISA).
The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene.
, NG20-like protein
, alternative name: G3a, NG20
, protein G3a
, protein Px