Apoptosis-Inducing, TAF9-Like Domain 1 Protéines (APITD1)

This locus represents naturally occurring read-through transcription between the neighboring APITD1 (apoptosis-inducing, TAF9-like domain 1) and CORT (cortistatin) genes. De plus, nous expédions Apoptosis-Inducing, TAF9-Like Domain 1 Anticorps (29) et Apoptosis-Inducing, TAF9-Like Domain 1 Kits (18) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
APITD1 378708 Q8N2Z9
APITD1 69928 Q9D084
Rat APITD1 APITD1 100534597  
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Top Apoptosis-Inducing, TAF9-Like Domain 1 Protéines sur anticorps-enligne.fr

Showing 6 out of 6 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,465.26
Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,465.26
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Levure Xenopus laevis His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,284.33
Détails
Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,293.50
Détails

APITD1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Plus protéines pour Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1) partenaires d'interaction

Human Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1) interaction partners

  1. The MHF complex, which is a heterotetramer that comprises two MHF1-MHF2 heterodimers, is remodeled by FANCM to favor recognition of branched DNA over dsDNA.

  2. CENP-S is not found in a soluble complex with its binding partner CENP-T (Montrer CENPT Protéines) but it interacts strongly and specifically with immobilized CENP-T (Montrer CENPT Protéines) in an in vivo binding assay.

  3. It discusses current knowledge of the biological roles of CENP-S and CENP-X (Montrer BHLHE40 Protéines) and how their dual existence may be a common feature of CCAN (constitutive centromere-associated network) proteins.

  4. A long, positively charged patch exposed on the surface of the (MHF1-MHF2) complex plays a critical role in double-stranded DNA binding to chromatin.

  5. MHF1 and MHF2 form a compact tetramer to which FANCM-F binds through a 'dual-V' shaped structure.

  6. provide biochemical evidence that MHF1 and MHF2 assemble into a heterodimer that binds DNA and enhances the DNA branch migration activity of FANCM.

  7. Mutations in APITD1 is not a common abnormality of neuroblastoma (Montrer ARHGEF16 Protéines) tumours.

  8. These results indicate that APITD1 is not the tumor suppressor gene on 1p36 responsible for the negative prognostic effect in uveal melanoma with concurrent loss of chromosome arm 1p, region 36, and chromosome 3.

  9. Results identified a centromere protein S (CENP-S)-containing subcomplex that includes the new constitutive kinetochore protein CENP-X (Montrer BHLHE40 Protéines).

Profil protéine Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1)

Profil protéine

This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7.

Gene names and symbols associated with APITD1

  • centromere protein S (CENPS)
  • centromere protein S (Cenps)
  • apoptosis-inducing, TAF9-like domain 1 (CENPS)
  • centromere protein S L homeolog (cenps.L)
  • apoptosis-inducing, TAF9-like domain 1 (APITD1)
  • centromere protein S (cenps)
  • 2610040C18Rik Protéine
  • 2810407L01Rik Protéine
  • apitd1 Protéine
  • CENP-S Protéine
  • cenps Protéine
  • FAAP16 Protéine
  • Mhf1 Protéine
  • zgc:194319 Protéine

Protein level used designations for APITD1

FANCM-interacting histone fold protein 1 , Fanconi anemia-associated polypeptide of 16 kDa , apoptosis-inducing TAF9-like domain-containing protein 1 , centromere protein S , apoptosis-inducing TAF9-like domain-containing protein 1 homolog , ortholog of human apoptosis-inducing, TAF9-like domain 1 APITD1 , CENP-S , apoptosis-inducing, TAF9-like domain 1 , FANCM associated histone fold protein 1

GENE ID SPECIES
378708 Homo sapiens
69928 Mus musculus
613732 Bos taurus
431958 Xenopus laevis
101114968 Ovis aries
100534620 Oryctolagus cuniculus
771417 Gallus gallus
100522376 Sus scrofa
100534597 Rattus norvegicus
487450 Canis lupus familiaris
569270 Danio rerio
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