anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2) Anticorps

ASAP2 encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. De plus, nous expédions ASAP2 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ASAP2 8853 O43150
ASAP2 211914 Q7SIG6
ASAP2 362719  
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Top anti-ASAP2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 34 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Chien Lapin Inconjugué WB Host: Rabbit Target Name: ASAP2 Sample Type: MCF7 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of DDEF2 expression in HEK293T (A), NS-1 (B), H9C2 (C) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of DDEF2 (Phospho-Ser701) using EGF treated RAW264.7 whole cell lysates 100 μL 11 to 12 Days
$450.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of ASAP2 using LOVO whole cell lysates 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué WB 100 μg 11 to 14 Days
$507.83
Détails
Humain Lapin Inconjugué ELISA, WB   100 μL 11 to 13 Days
$335.04
Détails
Humain Souris Inconjugué WB Western Blot analysis of ASAP2 expression in transfected 293T cell line by ASAP2 MaxPab polyclonal antibody.Lane1:DDEF2 transfected lysate(110.66 KDa).Lane2:Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué WB Western blot analysis DDEF2 (pS701) using EGF treated RAW264.7 whole cell lysates. 100 μg 11 to 16 Days
$454.83
Détails
Humain Lapin Inconjugué WB 100 μg 2 to 3 Days
$258.46
Détails
Humain Souris Inconjugué ELISA, WB DDEF2 polyclonal antibody (A01), Lot # 060501JCS1 Western Blot analysis of DDEF2 expression in SJCRH30 . Western Blot detection against Immunogen (36.89 KDa) . 50 μL 11 to 12 Days
$305.71
Détails

Plus d’anticorps contre ASAP2 partenaires d’interaction

Human ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2) interaction partners

  1. regulates multiple cytokine and growth factor-activated signaling pathways by acting as a recruitment factor for adapter proteins

Mouse (Murine) ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2) interaction partners

  1. these findings identify ASAP2 as a new target of Selk-dependent palmitoylation and reveal a new mechanism regulating the efficiency of FcgammaR-mediated phagocytosis.

  2. In conclusion, we have identified that ARL15 acts as an insulin-sensitizing effector molecule to upregulate the phosphorylation of members of the canonical IR/IRS1/PDPK1/AKT insulin pathway by interacting with its GAP ASAP2 and activating PDPK1. This research may provide new insights into GTPase-mediated insulin signalling regulation and facilitate the development of new pharmacotherapeutic targets for insulin sensitizati

ASAP2 profil antigène

Profil protéine

This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ASAP2

  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (ASAP2) anticorps
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 L homeolog (asap2.L) anticorps
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b (asap1b) anticorps
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (asap2) anticorps
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (Asap2) anticorps
  • 6530401G17Rik anticorps
  • AMAP2 anticorps
  • asap2 anticorps
  • CENTB3 anticorps
  • Ddef2 anticorps
  • Gm592 anticorps
  • Gm1523 anticorps
  • PAG3 anticorps
  • PAP anticorps
  • Pap-alpha anticorps
  • SHAG1 anticorps
  • si:dkey-37o8.2 anticorps

Protein level used designations for ASAP2

development and differentiation enhancing factor 2 , development- and differentiation-enhancing factor 2 , ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 , asap1 , PYK2 C terminus-associated protein , arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 , centaurin, beta 3 , development and differentiation-enhancing factor 2 , paxillin-associated protein with ARF GAP activity 3 , pyk2 C-terminus-associated protein

GENE ID SPECIES
768599 Gallus gallus
100072516 Equus caballus
431962 Xenopus laevis
459014 Pan troglodytes
475659 Canis lupus familiaris
565859 Danio rerio
618009 Bos taurus
699774 Macaca mulatta
100411588 Callithrix jacchus
100440164 Pongo abelii
100548947 Meleagris gallopavo
100560107 Anolis carolinensis
100604148 Nomascus leucogenys
8853 Homo sapiens
211914 Mus musculus
362719 Rattus norvegicus
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