Aryl Hydrocarbon Receptor Interacting Protein (AIP) Kits ELISA

The protein encoded by AIP is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. De plus, nous expédions AIP Anticorps (108) et AIP Protéines (12) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
AIP 9049 O00170
AIP 11632 O08915
AIP 282827 Q5FWY5
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Top AIP Kits ELISA sur

Showing 10 out of 18 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Souris 0.188 ng/mL 0.313-20 ng/mL Typical standard curve 96 Tests 12 to 14 Days
Rat 0.938 ng/mL 1.563-100 ng/mL Typical standard curve 96 Tests 12 to 14 Days
Lapin 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
Cobaye 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
Humain 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
Singe 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
Chien 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days

Plus Kits ELISA pour AIP partenaires d'interaction

Human Aryl Hydrocarbon Receptor Interacting Protein (AIP) interaction partners

  1. We propose a user-friendly risk categorisation system that can reliably group patients into high-risk, moderate-risk and low-risk groups for the presence of AIP mutations, thus providing guidance in identifying patients at high risk of carrying an AIP mutation. This risk score is based on a cohort with high prevalence of AIP mutations and should be applied cautiously in other populations.

  2. lack of AIP hinders the upregulation of PDE4A8 and PDE4A4 protein seen in sporadic somatotrophinomas.

  3. The novel missense mutation in the AIP gene, p.T171I, identified in a Chinese growth hormone (GH)-secreting Familial Isolated Pituitary Adenoma case, is a pathogenic variant that stimulated tumor cell proliferation and invasiveness and GH hypersecretion. The AIP-SSTR2-ZAC1 and AIP-IL-6-STAT3 pathways might be involved in these cell processes.

  4. AIP mutation is associated with familial pituitary adenoma syndromes.

  5. A missense variant in aryl hydrocarbon receptor-interacting protein (AIP) gene and a truncating mutation in multiple endocrine neoplasia I protein (MEN1) gene were both detected in the proband and his father, showing limited co-segregation with phenotype.

  6. The array was immunoscreened with serum from the patient in dilution 1:2000, and a strong signal on the array was identified as AIPL1, a protein with expression specifically restricted to the retina and the pineal gland.

  7. Earlier diagnosis of AIP-related acromegaly-gigantism cases enables timely clinical evaluation and treatment, thereby improving outcomes in terms of excessive linear growth and acromegaly comorbidities--{REVIEW}

  8. Therefore, both functional and structural studies reveal that N-terminus mutations in the AIP gene alter protein behaviour significantly and hence can truly be pathogenic in nature.

  9. This study of human fibroblasts bearing endogenous heterozygous AIP mutations and transfected pituitary GH3 cells shows that AIP mutations affect the AIP protein level and alter AhR transcriptional activity in a gene- and tissue-dependent manner.

  10. The expression of PDE4A4 and PDE4A8 in normal pituitary, their increased expression in adenomatous pituitary cells where AIP is meant to participate, and the disruption of the PDE4A4-AIP interaction by AIP mutants may play a role in pituitary tumorigenesis.

  11. The aryl hydrocarbon receptor interacting protein (AIP) founder mutation R304(*) is frequent in Mid Ulster, resulting in numerous acromegaly/gigantism cases.

  12. the well-known interaction between AIP and 2 different isoforms of phosphodiesterases (PDEs), PDE2A3 and PDE4A5, is of particular interest. While the interaction with over-expressed AIP does not seem to affect PDE2A3 function, the reported effect on PDE4A5 is, in contrast, reduced enzymatic activity.

  13. The c.805_825dup allele in AIP, originating from a common ancestor, associates with a severe clinical phenotype of gigantism.

  14. p.R3O4Q mutation, p.R304* mutation, and IVS3+1G>A mutation found in acromegaly cases

  15. The prevalence of AIP mutations in young Mexican patients with acromegaly is similar to that of European cohorts.

  16. Enhanced proteasomal degradation is a novel pathogenic mechanism for AIPmuts, with direct implications for the phenotype in pituitary adenomas.

  17. Case Report: truncating AIP mutation, p.W279*, in father/daughter presenting with familial isolated pituitary adenoma.

  18. A modest relationship was found between PPARalpha and AIP expression, both being significantly higher in the presence of pre-operative somatostatin analogues in somatotropinoma patients.

  19. The prevalence of AIP(mut) in Turkish patients was found to be 1 % in sporadic acromegaly in the present study.

  20. No digenism with AIP was identified among patients with sporadic pituitary adenomas.

Mouse (Murine) Aryl Hydrocarbon Receptor Interacting Protein (AIP) interaction partners

  1. Results demonstrated that Aip inactivation promoted somatotroph tumorigenesis and overproduction of growth hormone probably through increased Stat3 activation.

  2. Results provide novel evidence that AIP has an important role in the regulation of cAMP synthesis.

  3. XAP2 exerts a negative effect on ERalpha transcriptional activity and may thus prevent ERalpha-dependent events.

  4. Developmental control of apoptosis by the immunophilin aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin protein

  5. Mice with inactivation of aryl hydrocarbon receptor-interacting protein display complete penetrance of pituitary adenomas with aberrant ARNT expression.

  6. Data show that AIP is not required for the induction of the Cyp1a1 and Cyp1a2 genes.

  7. XAP2 hinders importin beta binding to the mAhR complex and represses the transactivation potential of the AhR by stabilizing the receptor complex and/or blocking nucleocytoplasmic shuttling of the AhR complex

  8. PPARalpha is in a complex with hsp90 and XAP2, and XAP2 appears to function as a repressor

  9. XAP2 has a role in stabilization of the dioxin receptor

  10. The role of Xap2 and C-terminal hsp-70 interacting protein on the endogenous Ah receptors expressed in mouse cell lines was determined.

  11. the role of ARA9 in cardiac development is independent of its interactions with its known xenobiotic receptor partners.

  12. expression level of ARA9 correlates with the frequency of a phenocopy of the Ahr-null allele supports the conclusion that the ARA9 protein is essential for AHR signaling during development

  13. XAP2 affects triiodothyronine-transcriptional repression of the hypothalamic gene, throtropin releasing hormone.

AIP profil antigène

Antigen Summary

The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.

Gene names and symbols associated with AIP

  • aryl hydrocarbon receptor interacting protein (AIP) anticorps
  • aryl hydrocarbon receptor interacting protein (aip) anticorps
  • aryl hydrocarbon receptor interacting protein (Aip) anticorps
  • aryl-hydrocarbon receptor-interacting protein (Aip) anticorps
  • AA408703 anticorps
  • AIP anticorps
  • Ara9 anticorps
  • AW476050 anticorps
  • D19Bwg1412e anticorps
  • Fkbp16 anticorps
  • FKBP37 anticorps
  • SMTPHN anticorps
  • wu:fa03h10 anticorps
  • xaip anticorps
  • XAP-2 anticorps
  • Xap2 anticorps
  • zgc:101101 anticorps

Protein level used designations for AIP

aryl hydrocarbon receptor interacting protein , AH receptor-interacting protein-like , AH receptor-interacting protein , HBV X-associated protein 2 , immunophilin homolog ARA9 , aryl-hydrocarbon receptor-interacting protein , HBV-X associated protein , immunophilin XAP2

451371 Pan troglodytes
100124770 Xenopus (Silurana) tropicalis
100407721 Callithrix jacchus
9049 Homo sapiens
334795 Danio rerio
395123 Gallus gallus
610467 Canis lupus familiaris
360190 Bos taurus
100723913 Cavia porcellus
101119947 Ovis aries
11632 Mus musculus
282827 Rattus norvegicus
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