Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (S. Cerevisiae) (ALG2) Kits ELISA

ALG2 encodes a member of the glycosyltransferase 1 family. De plus, nous expédions ALG2 Anticorps (55) et ALG2 Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Humain ALG2 ALG2 85365 Q9H553
Anti-Souris ALG2 ALG2 56737 Q9DBE8
Anti-Rat ALG2 ALG2 313231  
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Plus Kits ELISA pour ALG2 partenaires d'interaction

Human Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (S. Cerevisiae) (ALG2) interaction partners

  1. Lack of ALG-2 (Montrer PDCD6 Kits ELISA), ALIX (Montrer PDCD6IP Kits ELISA) or Vps4B (Montrer vps4b Kits ELISA) each prevents shedding, and repair of the injured cell membrane

  2. Results show the crystal structure of the complex between ALG-2 (Montrer PDCD6 Kits ELISA) and a peptide of Sec31A (Montrer SEC31A Kits ELISA) and found that the peptide binds to the third hydrophobic pocket (Pocket 3) and that ALG-2 (Montrer PDCD6 Kits ELISA) recognizing 2 types of motifs at different hydrophobic surfaces of Sec31A (Montrer SEC31A Kits ELISA).

  3. ALG-2 (Montrer PDCD6 Kits ELISA)/Sec31A (Montrer SEC31A Kits ELISA) interactions were not required for the localization of Sec31A (Montrer SEC31A Kits ELISA) to ER exit sites per se but appeared to acutely regulate the stability and trafficking of the cargo receptor p24 and the distribution of the vesicle tether protein p115 (Montrer ARHGAP4 Kits ELISA)

  4. ALG-2 (Montrer PDCD6 Kits ELISA) attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A (Montrer SEC31A Kits ELISA) complex.

  5. The results of in vitro binding assays using purified recombinant proteins indicated that ALG-2 (Montrer PDCD6 Kits ELISA) functions as a Ca(2 (Montrer CA2 Kits ELISA))-dependent adaptor protein that bridges ALIX (Montrer PDCD6IP Kits ELISA) and ESCRT-I (Montrer VPS28 Kits ELISA) to form a ternary complex

  6. This is the first report showing interaction of ALG-2 (Montrer PDCD6 Kits ELISA) with a P-body component (PATL1 (Montrer PATL1 Kits ELISA)).PATL1 (Montrer PATL1 Kits ELISA) as well as DCP1A (Montrer DCP1A Kits ELISA), a well-known P-body marker, co-localized with a subset of ALG-2 (Montrer PDCD6 Kits ELISA).

  7. We identify ALG14 (Montrer ALG14 Kits ELISA) and ALG2 (Montrer PDCD6 Kits ELISA) as novel genes in which mutations cause a congenital myasthenic syndrome

  8. the alg2 (Montrer PDCD6 Kits ELISA) binding site is one of the key determinants of the retention kinetics of Sec31A (Montrer SEC31A Kits ELISA) at endoplasmic reticulum exit sites

  9. found that targeting Requiem and Alg-2 (Montrer PDCD6 Kits ELISA) did not result in extended culture viability, but resulted in an increase in maximum viable cell numbers and cumulative IVCD under fed-batch conditions

  10. inability of the two-residue shorter ALG-2 (Montrer PDCD6 Kits ELISA) isoform to bind Alix (Montrer PDCD6IP Kits ELISA)

Mouse (Murine) Asparagine-Linked Glycosylation 2, alpha-1,3-Mannosyltransferase Homolog (S. Cerevisiae) (ALG2) interaction partners

  1. the observation that both ALG-2 (Montrer PDCD6 Kits ELISA) isoforms bind Mg2 (Montrer MCOLN1 Kits ELISA)+ with high affinity is the most significant finding of this study

  2. Thus, Alg2 (Montrer PDCD6 Kits ELISA), as a downstream mediator of Hivep3 (Montrer HIVEP3 Kits ELISA), suppresses osteogenesis, whereas it promotes chondrogenesis.

  3. ALG-2 (Montrer PDCD6 Kits ELISA) binding to Scotin (Montrer SHISA5 Kits ELISA) is strictly calcium dependent, indicating a role of this interaction in calcium signaling pathways

ALG2 profil antigène

Antigen Summary

This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ALG2

  • ALG2, alpha-1,3/1,6-mannosyltransferase (ALG2) anticorps
  • asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) (Alg2) anticorps
  • ALG2, alpha-1,3/1,6-mannosyltransferase (Alg2) anticorps
  • ALG2, alpha-1,3/1,6-mannosyltransferase L homeolog (alg2.L) anticorps
  • GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase (ALG2) anticorps
  • asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) (alg2) anticorps
  • 1110018A23Rik anticorps
  • 1300013N08Rik anticorps
  • ALPG2 anticorps
  • CDGIi anticorps
  • hALPG2 anticorps
  • im:7145131 anticorps
  • MNCb-5081 anticorps
  • NET38 anticorps

Protein level used designations for ALG2

GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase , GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase , GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase , alpha-1,3-mannosyltransferase ALG2 , alpha-1,3/1,6-mannosyltransferase ALG2 , asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase) , asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase) , asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog , asparagine-linked glycosylation protein 2 homolog , homolog of yeast ALG2 , hypothetical protein , LOW QUALITY PROTEIN: alpha-1,3/1,6-mannosyltransferase ALG2

GENE ID SPECIES
85365 Homo sapiens
56737 Mus musculus
313231 Rattus norvegicus
446622 Xenopus laevis
474780 Canis lupus familiaris
100113423 Sus scrofa
538899 Bos taurus
3647832 Candida albicans SC5314
403068 Danio rerio
100715517 Cavia porcellus
420998 Gallus gallus
100054840 Equus caballus
100353637 Oryctolagus cuniculus
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