anti-Ataxin 7-Like 2 Anticorps

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord.

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Réactivité
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47 Produits
ReactivitéHumain, Souris, Rat (Rattus)
Application WB
Détails de la commande Cat. No. ABIN632757
$517.86
50 μg
Plus shipping costs $45.00
Envoi sous 9 à 11 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application WB
Détails de la commande Cat. No. ABIN632758
$517.86
50 μg
Plus shipping costs $45.00
Envoi sous 9 à 11 jours ouvrables
ReactivitéHumain
Application FACS, WB
Détails de la commande Cat. No. ABIN5534922
$550.00
400 μL
Plus shipping costs $45.00
Envoi sous 2 à 3 jours ouvrables
ReactivitéBoeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Lapin, Rat (Rattus)
Application WB
Détails de la commande Cat. No. ABIN2774039
$229.00
100 μL
Plus shipping costs $45.00
Envoi sous 2 à 3 jours ouvrables
ReactivitéBoeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Lapin, Rat (Rattus)
Application WB
Détails de la commande Cat. No. ABIN2785259
$229.00
100 μL
Plus shipping costs $45.00
Envoi sous 2 à 3 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application ELISA, WB
Détails de la commande Cat. No. ABIN6258382
$390.77
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application WB
Détails de la commande Cat. No. ABIN2705524
$487.50
200 μL
Plus shipping costs $45.00
Envoi sous 13 à 14 jours ouvrables
ReactivitéHumain
Application EIA, WB
Détails de la commande Cat. No. ABIN950578
$522.50
0.4 mL
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Envoi sous 6 à 8 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application ELISA, WB
Détails de la commande Cat. No. ABIN2459636
$550.00
100 μL
Plus shipping costs $45.00
Envoi sous 2 à 3 jours ouvrables
ReactivitéBoeuf (Vache), Chien, Cobaye, Cheval, Humain, Singe, Souris, Porc, Lapin, Rat (Rattus)
Application WB
Détails de la commande Cat. No. ABIN6741233
$551.83
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 14 jours ouvrables
ReactivitéRoussette (Chauve-souris), Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Singe, Souris, Porc, Lapin, Rat (Rattus)
Application WB
Détails de la commande Cat. No. ABIN6743251
$551.83
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 14 jours ouvrables
ReactivitéHumain
Application IHC (p)
Détails de la commande Cat. No. ABIN5573201
$577.33
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application WB
Détails de la commande Cat. No. ABIN2982259
$309.53
Plus shipping costs $45.00
Envoi sous 11 à 16 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application IF (p), IHC (p), WB
Détails de la commande Cat. No. ABIN2170428
$327.80
100 μL
Plus shipping costs $45.00
Envoi sous 14 à 21 jours ouvrables
ReactivitéHumain, Souris, Rat (Rattus)
Application WB
Détails de la commande Cat. No. ABIN6710677
$350.00
100 μL
Plus shipping costs $45.00
Envoi sous 6 à 11 jours ouvrables
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Ataxin 7-Like 2 (ATXN7L2) profil antigène

Profil protéine

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the 'pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. This locus has been mapped to chromosome 3, and it has been determined that the diseased allele associated with spinocerebellar ataxia-7 contains 38-130 CAG repeats (near the N-terminus), compared to 7-17 in the normal allele. The encoded protein is a component of the SPT3/TAF9/GCN5 acetyltransferase (STAGA) and TBP-free TAF-containing (TFTC) chromatin remodeling complexes, and it thus plays a role in transcriptional regulation. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ATXN7L2

  • ataxin 7-like 2 (Atxn7l2) anticorps
  • ataxin 7 like 2 (ATXN7L2) anticorps
  • ataxin 7-like 2b (atxn7l2b) anticorps
  • ataxin 7-like 2a (atxn7l2a) anticorps
  • ataxin 7 like 2 (Atxn7l2) anticorps
  • 2610528J18Rik anticorps
  • atxn7l2 anticorps
  • RGD1307047 anticorps
  • wu:fi32b11 anticorps
  • wu:fi36e12 anticorps
  • zgc:92454 anticorps
  • zgc:136546 anticorps

Protein level used designations for ATXN7L2

ataxin-7-like protein 2 , mFLJ00381 protein , ataxin 7-like 1 , ataxin 7-like 2 , fi32b11

GENE ID SPECIES
72522 Mus musculus
127002 Homo sapiens
310781 Rattus norvegicus
436928 Danio rerio
457092 Pan troglodytes
490121 Canis lupus familiaris
541097 Bos taurus
701498 Macaca mulatta
692316 Danio rerio
100340504 Oryctolagus cuniculus
100581273 Nomascus leucogenys
100619233 Monodelphis domestica
100629633 Equus caballus
100718819 Cavia porcellus
100517342 Sus scrofa
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