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May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.. De plus, nous expédions et beaucoup plus de produits pour cette protéine.
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Encodes a mitochondrial protein (Montrer COX6B2 Anticorps)
Aurora-A (Montrer AURKA Anticorps) protein increased in stomach cancer cells in response to cisplatin and was degraded upon combined treatment with capsaicin with cisplatin.
Results describe the identification of a novel negative regulator of Aurora-A (Montrer AURKA Anticorps), named AIP (Aurora-A kinase Interacting Protein).
Phe31Ile polymorphism in Aurora A (Montrer AURKA Anticorps) may be a genetic modifier for developing breast carcinoma.
We propose that AURKAIP1 might function upstream of the Az1 (Montrer AZI1 Anticorps) by enhancing the binding affinity of Az1 (Montrer AZI1 Anticorps) to Aurora-A (Montrer AURKA Anticorps) to promote recognition, targeting to proteasome and subsequent degradation.
AKURA phosphorylation of AIP (Montrer AIP Anticorps) and stabilization of the enzyme-substrate complex are reported.
GSK-3beta modulates the early mitotic Aurora-A (Montrer AURKA Anticorps) level through binding and phosphorylating AIP (Montrer AIP Anticorps).
Plk1 controls Aurora A (Montrer AURKA Anticorps) localization and function by regulating cellular levels of hBora.
Aurora A (Montrer AURKA Anticorps) is necessary for the maintenance of the mitotic delay induced in response to microtubule-perturbing agents.
There exists an Ub-independent alternative pathway that promotesAurora-A degradation and AURKAIP1 promotes Aurora-A (Montrer AURKA Anticorps) degradation through this Ub-independent yet proteasome-dependent pathway.
May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.
aurora kinase A-interacting protein
, AURKA-interacting protein
, aurora kinase A interacting protein 1
, aurora-A kinase interacting protein
, Aurora-A kinase interacting protein