anti-B-Cell Scaffold Protein with Ankyrin Repeats 1 (BANK1) Anticorps

The protein encoded by BANK1 is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. De plus, nous expédions BANK1 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
BANK1 365948  
BANK1 242248 Q80VH0
BANK1 55024 Q8NDB2
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Top anti-BANK1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 29 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of BANK1 Antibody (Center) in HepG2 cell line lysates (35ug/lane). BANK1 (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué FACS, WB Western blot analysis of BANK1 Antibody in HepG2 cell line lysates (35ug/lane) Flow cytometric analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué WB Western blot analysis of extract of various cells, using BANK1 antibody. Western blot analysis of extracts of various cell lines, using BANK1 antibody (ABIN4903007) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s. 100 μL 11 to 13 Days
$366.77
Détails
Humain Lapin Inconjugué ELISA, WB   200 μL 11 to 16 Days
$658.43
Détails
Humain Lapin PE ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin APC ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin FITC ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin Alkaline Phosphatase (AP) ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin Biotin ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Détails
Humain Lapin Inconjugué IHC (p), WB Immunohistochemical staining of human lymph node with BANK1 polyclonal antibody  shows strong cytoplasmic positivity in lymphoid cells outside reaction centra. Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with BANK1 polyclonal antibody . 100 μL 11 to 12 Days
$637.32
Détails

anti-BANK1 Anticorps mieux référencés

  1. Human Polyclonal BANK1 Primary Antibody pour IHC, IHC (p) - ABIN4283023 : Bernal-Quirós, Wu, Alarcón-Riquelme, Castillejo-López: BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling. dans PLoS ONE 2013 (PubMed)

Plus d’anticorps contre BANK1 partenaires d’interaction

Mouse (Murine) B-Cell Scaffold Protein with Ankyrin Repeats 1 (BANK1) interaction partners

  1. B cell responses were enhanced due to decreased B cell scaffold protein with ankyrin repeats 1 (BANK1) levels in collagen-induced arthritis (CIA) mice.

  2. Bank1 and NF-kappaB as key regulators in anti-nucleolar antibody development

  3. The pre-B-cell receptor (pre-BCR) signaling molecules BLNK, BTK and BANK1 were positively regulated by the ZFP521 gene, leading to enhancement of the pre-BCR signaling pathway.

  4. Following CpG stimulation of B-cells, BANK1 loss reduced p38 phosphorylation (but not ERK or JNK), IL-6 secretion, & MNK1/2 and eIF4E phosphorylation. It had no effect on IL-6 mRNA stability. BANK1 does not affect release of eIF4E by phospho-4E-BP1.

  5. BANK attenuates CD40-mediated Akt activation, thereby preventing hyperactive B cell responses.

Human B-Cell Scaffold Protein with Ankyrin Repeats 1 (BANK1) interaction partners

  1. Study demonstrates the functional consequences of rare and low frequency missense variants in the interacting proteins BLK and BANK1, which are present alone, or in combination, in a substantial proportion of lupus patients. The rare variants found in patients, but not those found exclusively in controls, impair suppression of IRF5 and type-I IFN in human B cell lines.

  2. This study was the first to demonstrate that a BANK1 gene SNP (rs3733197) could confer genetic predisposition in polymyositis/dermatomyositis (PM/DM) patients and PM/DM patients with ILD in a Chinese Han population.

  3. Our data defines a minimal set of risk associated eQTLs predicted to be involved in the expression of BANK1 modulated through epigenetic regulation and splicing. These findings allow us to suggest that the increased expression of BANK1 will have an impact on B-cell mediated disease pathways.

  4. our results indicated that the BLK rs13277113 polymorphism was involved in the genetic background of RA in Chinese population and the association of BANK1 rs3733197 polymorphism with RA was dependent on the genotype of BLK rs13277113 polymorphism, highlighting B-cell response implicated in the pathogenesis of RA.

  5. This meta-analysis demonstrates that BANK1 rs10516487, rs3733197, and rs17266594 polymorphisms are associated with susceptibility to autoimmune diseases.

  6. Confirm the association of rs548234/ATG5, rs2736340/BLK and rs10516487/BANK1 with systemic lupus erythematosus in Chinese Han and reinforced our hypothesis of their epistasis effect in regulating B-cell signaling in SLE.

  7. The results of this study suggesting a mechanism for the involvement of BANK1 in the BOLD response to working memory

  8. Single-nucleotide polymorphism in BANK1 gene is associated with sclerotic graft-versus-host disease.

  9. The SLE susceptibility variants in the BANK1 gene may contribute to lupus by altering B cell signaling, increasing FOXO1 levels, and enhancing memory B cell development

  10. The systemic lupus erythematosus variant Ala71Thr of BLK severely decreases protein abundance and binding to BANK1 through impairment of the SH3 domain function.

  11. Data show that single-nucleotide polymorphism rs3733197 located in the coding region of BANK1 (B-cell scaffold protein with ankyrin repeats 1) was significantly associated with serum LDL cholesterols.

  12. Authors identified a novel balanced reciprocal translocation, t(4;14)(q24;q32.) Sequence analysis identified the partner gene as BANK1.

  13. Our study confirms evidence for epistasis between BLK and BANK1 in systemic lupus erythematosis from a Chinese population for the first time.

  14. Our findings suggest the existence of association between BANK1 gene and autoimmune thyroid diseases

  15. BANK1 and IL15 as new T1D genetic susceptibility factors.

  16. BANK1 and BLK have roles in B-cell signaling through phospholipase C gamma 2

  17. SNPs of the FAM167A-BLK region, but not the BANK1 SNPs, were associated with the development of primary Sjogren's syndrome in Han Chinese.

  18. This study confirms BANK1 as an RA susceptibility gene and for the first time provides evidence for epistasis between BANK1 and BLK in RA.

  19. This study did not reveal a major role for BANK1 in humoral autoimmunity in chronic arthritis.

  20. short Delta2 isoform of BANK1 displays a homogeneous cytoplasmic distribution

BANK1 profil antigène

Profil protéine

The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with BANK1

  • B-cell scaffold protein with ankyrin repeats 1 (Bank1) anticorps
  • B-cell scaffold protein with ankyrin repeats 1 (BANK1) anticorps
  • B cell scaffold protein with ankyrin repeats 1 (Bank1) anticorps
  • A530094C12Rik anticorps
  • AI451642 anticorps
  • AVIEF anticorps
  • BANK anticorps
  • LRRGT00104 anticorps

Protein level used designations for BANK1

B-cell scaffold protein with ankyrin repeats , B-cell scaffold protein with ankyrin repeats 1 , B-cell scaffold protein with ankyrin repeats 1 delta 2 transcript , B-cell scaffold protein with ankyrin repeats-like , b-cell scaffold protein with ankyrin repeats-like

GENE ID SPECIES
365948 Rattus norvegicus
422711 Gallus gallus
471260 Pan troglodytes
487881 Canis lupus familiaris
616565 Bos taurus
710040 Macaca mulatta
100014636 Monodelphis domestica
100067773 Equus caballus
100406794 Callithrix jacchus
100460856 Pongo abelii
100582890 Nomascus leucogenys
242248 Mus musculus
55024 Homo sapiens
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