anti-BCL2-Associated Athanogene 2 (BAG2) Anticorps

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. De plus, nous expédions BAG2 Protéines (11) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
BAG2 9532 O95816
BAG2 213539 Q91YN9
BAG2 690038  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-BAG2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 96 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-BAG2 Antibody Titration:  1.25ug/ml  Positive Control:  Jurkat cell lysate BAG2 is supported by BioGPS gene expression data to be expressed in Jurkat WB Suggested Anti-BAG2  Antibody Titration: 1.25 µg/mL  Positive Control: Jurkat cell lysate  BAG2 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL 2 to 3 Days
$229.00
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN184625 (0.3µg/ml) staining of Hela lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
$429.87
Détails
Humain Lapin Inconjugué IHC (p), WB Anti- BAG2 Picoband antibody,IHC(P) IHC(P): Human Pancreatic Cancer Tissue 100 μg 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué WB Anti-BAG2 antibody, Western blotting Lane 1: Rat Testis Tissue Lysate Lane 2: HELA Cell Lysate Lane 3: A549 Cell Lysate Lane 4: A431 Cell Lysate 100 μg 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded U87 xenograft, using BAG2, antibody at 1:500 dilution. WB Image Sample (30 ug of whole cell lysate) A: A431 B: HeLa 12% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), WB 100 μL 11 to 14 Days
$507.83
Détails
Humain Chèvre Inconjugué ELISA, WB 100 μg 11 to 14 Days
$610.50
Détails
Humain Lapin Inconjugué IHC, WB Immunohistochemical analysis of BAG2 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with Western blot analysis of BAG2 expression in Hela (A), Jurkat (B), HepG2 (C) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of BAG2 using Jurkat whole  lysates. 100 μL 11 to 12 Days
$390.77
Détails
Humain Chèvre Inconjugué WB   0.1 mg 4 to 8 Days
$478.50
Détails

anti-BAG2 Anticorps mieux référencés

  1. Human Polyclonal BAG2 Primary Antibody pour ICC, IF - ABIN4282947 : Dai, Qian, Li, McDonough, Borchers, Huang, Takayama, Younger, Ren, Cyr, Patterson: Regulation of the cytoplasmic quality control protein degradation pathway by BAG2. dans The Journal of biological chemistry 2005 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal BAG2 Primary Antibody pour IHC, WB - ABIN2775278 : Arndt, Daniel, Nastainczyk, Alberti, Höhfeld: BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP. dans Molecular biology of the cell 2005 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre BAG2 partenaires d’interaction

Human BCL2-Associated Athanogene 2 (BAG2) interaction partners

  1. High-regulated BAG2 is related to poor prognosis and could promote proliferation, invasion and migration of oral squamous cell carcinomas

  2. the nucleotide exchange factor (NEF) Bag2 stimulates SV40 release from Hsc70, thereby enabling successful virus arrival at the cytosol, which leads to infection. Hsp105, another NEF of Hsc70, displays a function overlapping that of Bag2, underscoring the importance of this release reaction.

  3. A comprehensive review of the structure, functions, and protein interactions of BAG2

  4. Data show that BAG2 Inhibits CHIP-Mediated HSP72 ubiquitination in aged cells.

  5. repression of BAG2 expression or BAG2 activity by cold-sensitive pathways, as modeled in undifferentiated and differentiated cells, respectively, may be a causal factor in the accumulation of cytotoxic hyperphosphorylated tau protein.

  6. NF-kappaB-mediated modulation of BAG2 expression regulates the shift between the neurotrophic and neurotoxic effects of Abeta1-42.

  7. Thus, BAG2 promotes mutant p53 accumulation and gain-of-function in tumor growth, metastasis and chemoresistance.

  8. This study showed that BAG2 (Bcl-2 associated athanogene family protein 2) and BAG5 (Bcl-2-associated athanogene family protein 5) stabilise pathogenic ataxin3-80Q by inhibiting its ubiquitination

  9. we measured the binding of human Hsp72 (HSPA1A) to BAG1, BAG2, BAG3, and the unrelated NEF Hsp105. These studies revealed a clear hierarchy of affinities: BAG3 > BAG1 > Hsp105 >> BAG2.

  10. this data correlate BAG2 to PINK1 for the first time, strengthening the important role of BAG2 in Parkinson disease -related neurodegeneration.

  11. BAG2 was directly phosphorylated at serine 20 in vitro by MAPKAPK2 and MAPKAP2 is also required for phosphorylation of BAG2 in vivo.

  12. BAG2 binds to the carboxyl terminus of Hsp70-interacting protein (CHIP) and provides a cochaperone-dependent regulatory mechanism for preventing unregulated ubiquitylation of misfolded proteins by CHIP

  13. The activity of BAG-2 resembles that of the previously characterized Hsc70 cochaperone and CHIP inhibitor HspBP1.

Mouse (Murine) BCL2-Associated Athanogene 2 (BAG2) interaction partners

  1. findings support the notion that BAG2 is an upstream regulator of the PINK1/PARKIN signaling pathway.

  2. Native Bag2-NTD crystals diffracted to 2.27 A resolution and belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 75.5, b = 84.7, c = 114.1 A

  3. Free and Hsc70-bound crystal structures of Bag2-BNB show its dimeric structure, in which a flanking linker helix and loop bind to Hsc70 to promote nucleotide exchange.

BAG2 profil antigène

Profil protéine

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Gene names and symbols associated with BAG2

  • BCL2 associated athanogene 2 (bag2) anticorps
  • BCL2 associated athanogene 2 (BAG2) anticorps
  • BCL-2-associated athanogene 2 (BAG2) anticorps
  • BCL2-associated athanogene 2 (bag2) anticorps
  • BCL2-associated athanogene 2 (Bag2) anticorps
  • Bcl2-associated athanogene 2 (Bag2) anticorps
  • 2610042A13Rik anticorps
  • ATBAG2 anticorps
  • BAG-2 anticorps
  • BAG2 anticorps
  • BC016230 anticorps
  • BCL-2-associated athanogene 2 anticorps
  • dJ417I1.2 anticorps
  • MGC89300 anticorps
  • MTG10.13 anticorps
  • MTG10_13 anticorps
  • zgc:64195 anticorps

Protein level used designations for BAG2

BCL2-associated athanogene 2 , BAG family molecular chaperone regulator 2 , putative BCL2-associated athanogene 2 , BAG-family molecular chaperone regulator-2 , bcl-2-associated athanogene 2 , dJ417I1.2 (BAG-family molecular chaperone regulator 2) , BAG-2

GENE ID SPECIES
448388 Xenopus (Silurana) tropicalis
462797 Pan troglodytes
100346462 Oryctolagus cuniculus
100190641 Taeniopygia guttata
836330 Arabidopsis thaliana
9532 Homo sapiens
393975 Danio rerio
421880 Gallus gallus
610506 Canis lupus familiaris
506107 Bos taurus
213539 Mus musculus
690038 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-BAG2 (BAG2) Anticorps
Avez-vous cherché autre chose?