anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) Anticorps

BNIP3L is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. De plus, nous expédions BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like Protéines (4) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
BNIP3L 665 O60238
BNIP3L 140923  
BNIP3L 12177 Q9Z2F7
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Top anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like Anticorps sur anticorps-enligne.fr

Showing 10 out of 106 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué WB 0.1 mg 6 to 8 Days
$687.50
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EIA, FACS, IF, IHC (p), WB Flow cytometric analysis of A549 cells using BNIP3L / BNIP3A Antibody (Center) Cat.-No AP52881PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of BNIP3L / BNIP3A Antibody (Center) Cat.-No AP52881PU-N with A549 cell followed by Alexa Fluor®488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of various cell lines, using BNIP3L antibody. 100 μL 11 to 13 Days
$366.77
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of various cell lines, using BNIP3L antibody (ABIN5973708) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded human stomach using BNIP3L antibody (ABIN5973708) at dilution of 1/100 (40x lens). 100 μL 11 to 16 Days
$426.40
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, WB Western blot analysis of BNIP3L using LOVO whole cell lysates ABIN6278198 staining HepG2? cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with BNIP3L antibody ABIN214415 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-BNIP3L antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 0.05 mg 11 to 14 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué IHC, ELISA, WB   100 μg 15 to 19 Days
$527.03
Détails
Humain Souris Inconjugué IP, ELISA, WB 100 μg 11 to 14 Days
$551.83
Détails

anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like Anticorps mieux référencés

  1. Human Polyclonal BNIP3L Primary Antibody pour WB - ABIN264993 : Matsushima, Fujiwara, Takahashi, Minaguchi, Eguchi, Tsujimoto, Suzumori, Nakamura: Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3. dans Genes, chromosomes & cancer 1998 (PubMed)
    Show all 9 Pubmed References

  2. Human Monoclonal BNIP3L Primary Antibody pour IF, ELISA - ABIN560088 : Nakamura, Kitamura, Shinogi, Yoshida, Goda, Murai, Kamino, Arakawa: BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria. dans PLoS ONE 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal BNIP3L Primary Antibody pour IHC, IHC (p) - ABIN4285004 : Li, Zhang, Zhuang, Chen, Chen, Tian, Wu, Li, Wang, Zhang, Chen, Li, Zhao, Sui, Hu, Feng: MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX. dans The Journal of biological chemistry 2014 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal BNIP3L Primary Antibody pour IHC, ELISA - ABIN1001910 : Yasuda, Han, Dionne, Boyd, Chinnadurai: BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3. dans Cancer research 1999 (PubMed)
    Show all 4 Pubmed References

  5. Human Polyclonal BNIP3L Primary Antibody pour IF, IHC (p) - ABIN542828 : Metukuri, Beer-Stolz, Namas, Dhupar, Torres, Loughran, Jefferson, Tsung, Billiar, Vodovotz, Zamora: Expression and subcellular localization of BNIP3 in hypoxic hepatocytes and liver stress. dans American journal of physiology. Gastrointestinal and liver physiology 2009 (PubMed)

Plus d’anticorps contre BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like partenaires d’interaction

Human BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) interaction partners

  1. The results demonstrate that Nix can serve as an alternative mediator of mitophagy to maintain mitochondrial turnover, identifying Nix as a promising target for neuroprotective treatment in PINK1/Parkin-related Parkinson's disease.

  2. Here the authors present evidence for phosphorylation-driven regulation of the Nix:LC3B interaction. Isothermal titration calorimetry and NMR indicate a ~100 fold enhanced affinity of the serine 34/35-phosphorylated Nix LC3-interacting region (LIR) to LC3B and formation of a very rigid complex compared to the non-phosphorylated sequence.

  3. The authors find that KDM3A promotes anoikis through transcriptional activation of BNIP3 and BNIP3L, which encode pro-apoptotic proteins.

  4. p75(NTR) and NIX may play critical roles in intracerebral hemorrhage-induced neuronal apoptosis in vitro and in vivo.

  5. Data suggest that targeting BNIP3L protein in wild-type p53 tumor suppressor colon cancer cells is an anticancer strategy activating iron depletion signaling and the mitophagy-related cell death pathway.

  6. regulates mitophagy during hypoxia, whereas NIX is required for mitophagy during development of the erythroid lineage.

  7. Nix protein positively regulates NF-kappaB activation in gliomas

  8. The physical interaction of Mieap, BNIP3 and NIX at the mitochondrial outer membrane may play a critical role in the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix.

  9. mitochondrial ROS and NIX are essential factors for Mieap-induced accumulation of lysosome-like organelles within mitochondria

  10. Nix functions as an autophagy receptor, which mediates mitochondrial clearance after mitochondrial damage and during erythrocyte differentiation

  11. NIX binds to TSAP6 in tumor cells and has a role in apoptosis

  12. The proapoptotic factor Nix is a highly regulated effector of growth during terminal erythroid maturation.

  13. Bnip3L, capable of attenuating tumorigenicity, mediates p53-dependent apoptosis under hypoxia.

  14. pro-apoptotic proteins BNip3 and Nix are expressed in the human placenta

  15. NIX is required for the selective elimination of mitochondria, however, because mitochondrial clearance, in the absence of NIX, is arrested at the stage of mitochondrial incorporation into autophagosomes and autophagosome maturation.

  16. Results report that oxygen deprivation can activate the autophagic pathway in human cancer cell lines via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L.

  17. Homozygous deletions in a number of biologically important genes were found in prostate cancer cell lines, including PPP2R2A and BNIP3L identified in this study.

  18. Results suggest that hypoxia-induced autophagy via BNIP3 and BNIP3L is clearly a survival mechanism that promotes tumor progression.

Mouse (Murine) BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) interaction partners

  1. Bnip3l knockout (bnip3l(-/-)) impaired mitophagy and aggravated cerebral I-R (ischemia-reperfusion) injury in mice, which can be rescued by BNIP3L overexpression. The rescuing effects of BNIP3L overexpression can be observed in park2(-/-) mice, which showed mitophagy deficiency after I-R.

  2. mitophagy is dependent on the mitochondrial outer membrane receptor BNIP3L/NIX but not on mitochondrial membrane potential (DeltaPsim) dissipation and functions in an important role during the reprogramming process.

  3. studies highlight a new hypoxia-induced pathway in which NANOG activates BNIP3L expression, contributing to autophagy induction in hypoxic tumor cells and their resistance to killing by CTL

  4. miR-30e protects mitochondria and podocytes from aldosterone induced apoptosis by targeting BNIP3L expression.

  5. Bnip3L and caspase-12 identified by the PCR arrays at both catagen stages were additionally localized using immunofluorescence and were reported in physiological hair development for the first time.

  6. our study demonstrates that BNIP3L, as a substrate of PARK2, promotes mitophagy in the PINK1/PARK2 pathway associated with PD pathogenesis.

  7. role in the generation of robust NK cell memory in the process of mitophagy during viral infection

  8. Suggest Nix is a novel mediator of norepinephrine-induced fibrosis.

  9. MicroRNA-137 has a role in inhibiting mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX

  10. -stimulated cytoplasmic-nuclear shuttling of the alternately spliced non-mitochondrial Nix isoform and uncover a role for sNix as a modulator of TNFalpha/NFkappaB-stimulated cardiac gene expression

  11. BNIP3L activity localizes to a small region in its cytoplasmic domain, the minimal essential region (MER).

  12. These results establish Nix as a critical mediator of beta cell apoptosis and programmed necrosis in Pdx1-deficient diabetes.

  13. molecular events responsible for the different phases of mitophagy and placed Nix upstream of the events

  14. Mitochondrial Nix activates Bax/Bak- and caspase-dependent apoptosis, whereas ER-Nix activates Bax/Bak-independent, MPTP-dependent necrosis.

  15. Nix functions as an autophagy receptor, which mediates mitochondrial clearance after mitochondrial damage and during erythrocyte differentiation

  16. induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy

  17. Up-regulation of myocardial Nix and BNip3 is associated with apoptosis in cardiac hypertrophy and ischemia, respectively.

  18. Nix promotes cell death via interaction with POSH and activation of the JNK/c-Jun pathway and that Nix protein is induced and contributes to cell death in a cellular model of Parkinson disease

  19. Nix is identified as the critical proapoptotic mediator within the erythrocyte lineage; Nix null mice are viable and fertile.

  20. Bnip3/Bnip3L play a crucial role in anthrax lethal toxin-induced cytotoxicity, and down-regulation of Bnip3/Bnip3L is a mechanism of spontaneous or toxin-induced resistance of macrophages.

BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) profil antigène

Profil protéine

This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein counteracts the apoptotic inducer BNIP3 and may play a role in tumor suppression.

Gene names and symbols associated with BNIP3L

  • BCL2 interacting protein 3 like (BNIP3L) anticorps
  • BCL2 interacting protein 3 like (Bnip3l) anticorps
  • BCL2/adenovirus E1B interacting protein 3-like (Bnip3l) anticorps
  • BCL2/adenovirus E1B interacting protein 3-like a (bnip3la) anticorps
  • BNIP3a anticorps
  • bnip3l2 anticorps
  • C86132 anticorps
  • D14Ertd719e anticorps
  • Nip3L anticorps
  • Nix anticorps
  • wu:fb52b03 anticorps
  • wu:fc02h04 anticorps

Protein level used designations for BNIP3L

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like , BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A , BCL2/adenovirus E1B 19-kd protein-interacting protein 3a , NIP3-like protein X , NIP3L , adenovirus E1B19k-binding protein B5 , BCL2/adenovirus E1B 19 kDa-interacting protein 3-like , BCL2/adenovirus E1B 19kDa-interacting protein 3-like , BCL2/adenovirus E1B 19kD-interacting protein 3-like , BCL2/adenovirus E1B interacting protein 3-like, 2 , Nix

GENE ID SPECIES
665 Homo sapiens
140923 Rattus norvegicus
12177 Mus musculus
534615 Bos taurus
100152675 Sus scrofa
100733852 Cavia porcellus
323563 Danio rerio
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