BCL6 Co-Repressor (BCOR) Kits ELISA

The protein encoded by BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. De plus, nous expédions BCOR Anticorps (74) et BCOR Protéines (7) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
BCOR 54880 Q6W2J9
Anti-Rat BCOR BCOR 317346  
BCOR 71458 Q8CGN4
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Plus Kits ELISA pour BCOR partenaires d'interaction

Human BCL6 Co-Repressor (BCOR) interaction partners

  1. BCOR rearranged high grade endometrial stromal sarcoma has distinct morphological features and aggressive clinical behavior

  2. A new term of X-linked BCOR-related syndrome.

  3. Letter: diffuse strong nuclear labeling for BCOR occurs in pediatric clear cell sarcoma of the kidney.

  4. Detection of fusion transcripts BCOR-CCNB3 in the bone marrow suggests that undifferentiated sarcoma patients with positive findings are at high risk of tumor progression.

  5. The C terminus of BCOR regulates the assembly and targeting of the PRC1.1 complex, while the N terminus contributes to BCOR-PRC1.1 repressor function.

  6. co-expression of KPNA2, KPNA4, or KPNA6 with BCOR carrying a previously described mutation which eliminated one of the two nuclear localization signals significantly increased nuclear accumulation of the mutant BCOR.

  7. Report a series of BCOR-CCNB3 fusion sarcomas, highlighting the significant morphologic, immunohistochemical and transcriptional overlap with other primitive round/spindle cell sarcomas.

  8. Suggest that uterine neoplasms with BCOR internal tandem duplication be regarded as a unique subtype of high-grade uterine sarcoma, possibly within the family of endometrial stromal neoplasia.

  9. BCOR-ITDs define a rare subset of pediatric sarcomas and clinically aggressive endometrial stromal sarcoma cases, as defined by NGS for the first time.

  10. BCOR-ITD was positively detected in the cfDNA of two cases, both of which were later diagnosed as CCSK based on histological feature of the resected tumor specimen, while it was not detected for a normal control and a patient diagnosed with Wilms' tumor.

  11. Multivariate analysis demonstrated that BCOR mutations were an independent unfavorable prognostic factor (P = 0.0038, P = 0.0463) for both OS and RFS.

  12. BCOR mutation is associated with tooth agenesis.

  13. The majority of the cases of clear cell sarcoma of the kidney in our cohort had BCOR internal tandem duplications

  14. BCOR was negative in all ewing sarcoma family of tumors

  15. BCOR immunohistochemical staining is a highly sensitive marker for YWHAE-NUTM2 high-grade endometrial stromal sarcoma with both classic and unusual morphology and identifies a subset of high-grade endometrial stromal sarcoma with BCOR alterations, including BCOR rearrangement and internal tandem duplication.

  16. the frequent BCOR mutations and the absence of alterations in genes regulating the NF-kappaB pathway (triple-negative for KLF2, TNFAIP3 and MYD88 mutations) or the absence of a BRAF mutation appear to delineate a specific genetic pattern of SDRPL, which is distinct from that already identified in SMZL, HCL or HCL-v.

  17. BCOR internal tandem duplication and/or nuclear immunoreactivity for BCOR or BCL6 can aid in the diagnosis of primitive myxoid mesenchymal tumor of infancy and help to differentiate it from congenital infantile fibrosarcoma.

  18. Case Report: altered BCOR expression and homogeneous coactivation of both the SHH and WNT signaling pathways, and suggest potential novel therapeutic approaches for patients with a high grade neuroepithelial tumor of the central nervous system with BCOR alteration diagnosis.

  19. Immunohistochemistry for either CCNB3 or BCOR is not completely sensitive and specific in undifferentiated sarcoma with BCOR-CCNB3 fusion.

  20. Case Reports: renal sarcomas with BCOR-CCNB3 gene fusion showing histological overlap with BCOR-related clear cell sarcoma of the kidney.

Mouse (Murine) BCL6 Co-Repressor (BCOR) interaction partners

  1. Our results demonstrate that Bcor mutations collaborate with NUP98-PHF23 to induce pro-B1 acute lymphoblastic leukemia

  2. results reveal a tumor suppressor function of BCOR in myeloid malignancies and highlight the impact of Bcor insufficiency on the initiation and progression of MDS.

  3. This study provides mechanistic understanding of how BCOR regulates cell fate decisions and how loss of function contributes to the development of leukaemia.

  4. Genomic characterization of Emu-Myc mouse lymphomas identifies Bcor as a Myc cooperative tumor-suppressor gene.

  5. results provide the first evidence of a tumor suppressor role for BCOR in the pathogenesis of T lymphocyte malignancies

  6. Data show that BCL6 interacting corepressor Bcor Is Specifically Down-regulated by Activin Signaling in trophoblast stem cells (TSCs).

  7. T cell-expressed BCOR is critical for optimal GC-Tfh cell differentiation and humoral immunity.

  8. IRF8 pairs with BCL6 co-repressor BCOR in the nucleus to enhance its transcriptional repressive activity.

  9. Results suggest that Bcor expressed in the mesenchyme plays crucial roles during early tooth development.

  10. Study isolated an Fbxl10/Jhdm1B complex by Study using a high throughput proteomics approach identified interactors with Rnf2 including Fbxl10/Jhdm1B, casein kinase subunits, and the BcoR corepressor

  11. Bcor plays a role in differentiation of multiple tissue lineages during early embryonic development.

BCOR profil antigène

Antigen Summary

The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.

Gene names and symbols associated with BCL6 Co-Repressor (BCOR) Kits ELISA

  • BCL6 corepressor (BCOR) anticorps
  • BCL6 corepressor (bcor) anticorps
  • BCL6 co-repressor (Bcor) anticorps
  • BCL6 interacting corepressor (Bcor) anticorps
  • 5830466J11Rik anticorps
  • 8430401K06Rik anticorps
  • ANOP2 anticorps
  • BCOR anticorps
  • BcorR anticorps
  • D930024N20Rik anticorps
  • MAA2 anticorps
  • MCOPS2 anticorps
  • mKIAA1575 anticorps
  • RGD1562735 anticorps

Protein level used designations for BCL6 Co-Repressor (BCOR) Kits ELISA

BCL-6 corepressor , BCL-6 interacting corepressor , BCL6 co-repressor , Bcl6 interacting corepressor

54880 Homo sapiens
100050335 Equus caballus
698644 Macaca mulatta
784529 Bos taurus
402921 Danio rerio
418574 Gallus gallus
317346 Rattus norvegicus
480880 Canis lupus familiaris
465574 Pan troglodytes
71458 Mus musculus
100154380 Sus scrofa
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