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BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. De plus, nous expédions BRMS1 Protéines (8) et BRMS1 Kits (4) et beaucoup plus de produits pour cette protéine.
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Human Monoclonal BRMS1 Primary Antibody pour IP, ELISA - ABIN565191
Liu, Smith, Jones: Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis. dans Molecular and cellular biology 2006
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Human Polyclonal BRMS1 Primary Antibody pour WB - ABIN1881120
Wu, McEwen, Harihar, Baker, DeWald, Zhou: BRMS1 expression alters the ultrastructural, biomechanical and biochemical properties of MDA-MB-435 human breast carcinoma cells: an AFM and Raman microspectroscopy study. dans Cancer letters 2010
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The RAS-related nuclear protein (Montrer RAN Anticorps) ((P) ran), breast cancer metastasis suppressor 1 ((P) brms1) and minichromosome maintenance complex component 5 (Montrer MCM5 Anticorps) ((P) mcm5 (Montrer MCM5 Anticorps)) promoters have the specificity and strength needed for cancer-specific expression-targeted gene therapy.
we identify a therapeutically exploitable posttranslational mechanism by which CK2alpha-mediated degradation of BRMS1 promotes metastases in lung cancer
our study characterized DAPK1 (Montrer DAPK1 Anticorps) as a novel transcriptional target of BRMS1. Transcriptional activation of DAPK1 (Montrer DAPK1 Anticorps) might be another important mechanism accounting for the metastasis suppressive activity of BRMS1.
BRMS1 promoter methylation and aberrant protein expression seem to be related to high-risk types of human papilloma virus-induced carcinogenesis in uterine cervix.
miR (Montrer MLXIP Anticorps)-346 promotes migration and invasion of nasopharyngeal carcinoma cells via targeting BRMS1.
expression of BRMS1 and/or HPA (Montrer HPSE Anticorps) might be closely related to the carcinogenesis, clinical biological behaviors, and prognosis of gallbladder adenocarcinoma
A novel link has been discussed between CDK2 (Montrer CDK2 Anticorps) expression and cell migration by characterizing the CDK2 (Montrer CDK2 Anticorps)-mediated phosphorylation of BRMS1.
Phosphorylation of BRMS1 by CDK2 (Montrer CDK2 Anticorps) regulates the migration of tumor cells.
Data show that Cullin3 exerts its function through promoting breast-cancer metastasis suppressor 1 (BRMS1) protein degradation, which was associated with epithelial-mesenchymal transition (EMT (Montrer ITK Anticorps)), migration and invasion.
The studies reviewed here with respect to BRMS1 structure, cellular effects, intracellular signaling, and clinical value consolidate the importance of BRMS1 in the development of metastasis.
findings indicate the expression of Brms1L (Montrer BRMS1L Anticorps) depends on beta-catenin (Montrer CTNNB1 Anticorps) activity and contributes to follicle stimulating hormone beta (Montrer FSHB Anticorps) induction by Gonadotropin-Releasing Hormone.
The Brms1 suppressed pulmonary metastasis and promoted apoptosis of tumor cells located in the lungs but not in the mammary glands.
BRMS1 may participate in transcriptional regulation via interaction with the mSin3.HDAC (Montrer HDAC3 Anticorps) complex
results show for the first time that BRMS1 contains both nuclear import and export signals enabling its nucleo-cytoplasmic shuttling
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
breast cancer metastasis suppressor 1
, breast cancer metastasis-suppressor 1
, breast cancer metastasis-suppressor 1 homolog
, breast cancer metastasis-suppressor 1-like protein