anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) Anticorps

BUB1 encodes a kinase involved in spindle checkpoint function. De plus, nous expédions BUB1 Protéines (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
BUB1 699 O43683
BUB1 296137  
BUB1 12235 O08901
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Top anti-BUB1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 161 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué ELISA, FACS, WB Western blot analysis using BUB1 mAb against human BUB1 (AA: 1-130) recombinant protein. (Expected MW is 41.3 kDa) Western blot analysis using BUB1 mAb against HEK293 (1) and BUB1 (AA: 1-130)-hIgGFc transfected HEK293 (2) cell lysate. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$561.00
Détails
Humain Lapin Inconjugué WB Observed bind size: 122KD Anti-Bub1 Picoband antibody,  All lanes: Anti BUB1  at 0.5ug/ml WB: Recombinant Human BUB1 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Souris Souris Inconjugué ICC, FACS, IF, IHC (p), WB 50 μL Connectez-vous pour afficher 7 to 8 Days
$455.57
Détails
Humain Lapin Inconjugué IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BUB1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué FACS, WB BUB1A Antibody (N-term) (ABIN651630) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the BUB1A antibody detected the BUB1A protein (arrow). BUB1A Antibody (N-term) (ABIN651630) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma BUB1A Antibody (F1058) (ABIN392626) western blot analysis in T47D cell line lysates (35 µg/lane).This demonstrates the BUB1A antibody detected the BUB1A protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p) 100 μL Connectez-vous pour afficher 11 to 14 Days
$493.17
Détails
Humain Lapin Inconjugué IHC (p), WB 50 μg Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué ICC, ELISA, WB   100 μg Connectez-vous pour afficher 15 to 19 Days
$523.71
Détails

BUB1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-BUB1 Anticorps mieux référencés

  1. Mouse (Murine) Monoclonal BUB1 Primary Antibody pour ICC, FACS - ABIN108553 : Liu, Hittle, Jablonski, Campbell, Yoda, Yen: Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. dans Nature cell biology 2003 (PubMed)
    Show all 4 Pubmed References

  2. Mouse (Murine) Monoclonal BUB1 Primary Antibody pour ICC, FACS - ABIN108554 : Qi, Tang, Yu: Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1. dans Molecular biology of the cell 2006 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal BUB1 Primary Antibody pour ICC, ELISA - ABIN1001946 : Williams, Roberts, Gjoerup: Bub1: escapades in a cellular world. dans Cell cycle (Georgetown, Tex.) 2007 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal BUB1 Primary Antibody pour ICC, ELISA - ABIN1001947 : Meraldi, Sorger: A dual role for Bub1 in the spindle checkpoint and chromosome congression. dans The EMBO journal 2005 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal BUB1 Primary Antibody pour IF, IP - ABIN2477744 : Vlasveld, Rankin, Hekman, Rodenhuis, Beijnen, Hilton, Dubbelman, Vyth-Dreese, Melief: A phase I study of prolonged continuous infusion of low dose recombinant interleukin-2 in melanoma and renal cell cancer. Part I: Clinical aspects. dans British journal of cancer 1992 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal BUB1 Primary Antibody pour IHC, IHC (p) - ABIN4993905 : Aggarwal, Kruczynski, Frankfurter, Correia, Lobert: Murine leukemia P388 vinorelbine-resistant cell lines are sensitive to vinflunine. dans Investigational new drugs 2008 (PubMed)

  7. Human Monoclonal BUB1 Primary Antibody pour ICC, IF - ABIN2668285 : Liu, Rattner, Jablonski, Yen: Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells. dans The Journal of cell biology 2006 (PubMed)

Plus d’anticorps contre BUB1 partenaires d’interaction

Human Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) interaction partners

  1. Small sequence differences in Bub1 and BubR1 (Montrer BUB1B Anticorps) direct Bub3 (Montrer BUB3 Anticorps) to different phosphorylated targets in the spindle assembly checkpoint signaling cascade.

  2. MiR (Montrer MLXIP Anticorps)-490-5p could regulate TGFbeta (Montrer TGFB1 Anticorps)/Smad (Montrer SMAD1 Anticorps) signaling pathways by inhibiting BUB1.

  3. Therefore, Mps1 (Montrer IDUA Anticorps) promotes checkpoint activation through sequentially phosphorylating Knl1 (Montrer CASC5 Anticorps), Bub1, and Mad1 (Montrer MXD1 Anticorps). This sequential multi-target phosphorylation cascade makes the checkpoint highly responsive to Mps1 (Montrer IDUA Anticorps) and to kinetochore-microtubule attachment.

  4. Chromosomal rearrangement resulting in BUB1 haploinsufficiency identified in a patient with polycystic liver disease. BUB1 may imply germline causes of genetic instability in PLD (Montrer PLD Anticorps).

  5. Results report that BubR1 (Montrer BUB1B Anticorps) and RepoMan bind directly to PP2A (Montrer PPP2R4 Anticorps)-B56 using an LSPIxE short linear motif (SLiM), where phosphorylation of the Ser (Montrer SIGLEC1 Anticorps) residue enhances binding. RepoMan and BubR1 (Montrer BUB1B Anticorps) bind B56 using both hydrophobic and electrostatic interactions.

  6. Inhibition of Bub1 kinase impaired chromosome arm resolution but exerted only minor effects on mitotic progression or spindle assembly checkpoint function.

  7. Study shows that BUB1beta (Montrer BUB1B Anticorps) and PDZ binding kinase (Montrer PBK Anticorps) are up-regulated in breast cancer tumors and their expression is associated with improved overall survival (OS) in basal-like tumors but worse OS in luminal and untreated patients.

  8. Bub1 may be associated with cancer stem cell potential.

  9. Both Bub1 and BubR1 (Montrer BUB1B Anticorps) bind stably to Bub3 (Montrer BUB3 Anticorps) that is required for kinetochore localization of the proteins

  10. Bub1-Plk1 (Montrer PLK1 Anticorps)-mediated phosphorylation of Cdc20 (Montrer CDC20 Anticorps) constitutes an anaphase-promoting complex or cyclosome-inhibitory mechanism that is parallel, but not redundant, to mitotic checkpoint (Montrer BUB3 Anticorps) complex formation.

Mouse (Murine) Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) interaction partners

  1. Bub1 coordinates checkpoint signalling by distinct domains for RZZ and BubR1 (Montrer BUB1B Anticorps) recruitment and localizes antagonistic checkpoint activities.

  2. It was shown that that Bub1 kinase activity integrates attachment error correction and mitotic checkpoint signaling by controlling the localization and activity of Aurora B kinase through phosphorylation of histone H2A at threonine 121.

  3. Results establish that Bub1 has oncogenic properties and suggest that Aurora B (Montrer AURKC Anticorps) is a critical target through which overexpressed Bub1 drives aneuploidization and tumorigenesis.

  4. It seems that Sgo1 (Montrer SGOL1 Anticorps) sets up the centromeric protection mechanism in G2, but that its Bub1-dependent localisation to centromeres during mitosis is not required to maintain cohesion.

  5. mutations of Bub1 and BubR1 (Montrer BUB1B Anticorps) found in Brca2 (Montrer BRCA2 Anticorps)- mutant mice indeed are responsible for the chromosome instability in Brca2 (Montrer BRCA2 Anticorps)-mutated tumors

  6. Our data suggest that Bub1 is a critical spindle checkpoint protein that regulates accurate chromosome alignment and homolog disjunction in mammalian oocyte meiosis.

  7. Bub1 is important for mediating cell death when chromosomes missegregate.

  8. Bub1 is essential for proper chromosome segregation, a defect that can lead to severe phenotypes, including perinatal lethality and a predisposition to cancer.

  9. Data show that the anaphase-promoting complex is activated in an exponential fashion after germinal vesicle breakdown in oocytes and that this process is advanced by 5 hr in oocytes lacking Bub1.

  10. Bub1 dysfunction is linked to inherited aneuploidy in female germ cells and may contribute to the maternal age-related increase in aneuploidy and pregnancy loss.

BUB1 profil antigène

Profil protéine

This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.

Gene names and symbols associated with BUB1

  • BUB1 mitotic checkpoint serine/threonine kinase (BUB1) anticorps
  • BUB1 mitotic checkpoint serine/threonine kinase (bub1) anticorps
  • BUB1 mitotic checkpoint serine/threonine kinase (Bub1) anticorps
  • BUB1, mitotic checkpoint serine/threonine kinase (Bub1) anticorps
  • AL022991 anticorps
  • Bub1a anticorps
  • BUB1L anticorps
  • C80208 anticorps
  • D2Xrf87 anticorps
  • hBUB1 anticorps
  • xbub1 anticorps

Protein level used designations for BUB1

BUB1 budding uninhibited by benzimidazoles 1 homolog , mitotic checkpoint serine/threonine-protein kinase BUB1 , budding uninhibited by benzimidazoles 1 , budding uninhibited by benzimidazoles 1 homolog , mitotic spindle checkpoint kinase , putative serine/threonine-protein kinase , mBUB1

GENE ID SPECIES
100064049 Equus caballus
459484 Pan troglodytes
780291 Xenopus (Silurana) tropicalis
699 Homo sapiens
296137 Rattus norvegicus
12235 Mus musculus
100682599 Canis lupus familiaris
514777 Bos taurus
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