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Receptor for KLRB1B that protects target cells against natural killer cell-mediated lysis..
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CLEC-2 is an adhesive receptor that supports platelet arrest to podoplanin under venous shear. Src/Syk-dependent signalling stabilises platelet adhesion to podoplanin.
Both circulating B lymphocytes and CD11b-high Gr-1-high myeloid cells lose CLEC-2 following entry into secondary lymphoid organs.
aggretin may induce cytokine TNF-alpha/IL-6 release via interacting with CLEC-2 receptor and the subsequent MAPK and NF-kappaB activation in monocytes/macrophages
Data suggest that DDV10 is the long form of Clec2 g (Clec2g-L), and DDV10/Clec2g-L may play a role in the stratification and/or cornification of epithelial cells during differentiation.
Receptor for KLRB1B that protects target cells against natural killer cell-mediated lysis.
C-type lectin domain family 2 member D11
, C-type lectin domain family 2, member d11
, C-type lectin-related protein 11
, C-type lectin-related protein B
, Ocil/Clrb-like protein
, lectin-like transmembrane protein
, osteoclast inhibitory lectin
, C-type lectin domain family 2 member G
, C-type lectin-related protein C
, C-type lectin-related protein x variant 1
, ocil-related protein 1
, osteoclast inhibitory lectin related protein
, osteoclast inhibitory lectin-related protein 1