anti-C-Type Lectin Domain Family 4, Member M Anticorps

CLEC4M encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver.

Qualité de données
  • 16
Type
  • 35
    Primary
Antigène
  • 35
Réactivité
  • 35
  • 12
  • 10
  • 4
  • 2
Application
  • 22
  • 11
  • 11
  • 5
  • 5
Hote
  • 30
  • 5
Clonalité
  • 29
  • 5
  • 1
Clone
  • 3
  • 1
  • 1
Epitope
  • 4
  • 4
  • 3
  • 3
  • 2
Conjugué
  • 25
  • 2
  • 1
  • 1
  • 1
Isotype
  • 13
  • 3
  • 1
  • 1
  • 1
Type Proteine
  • 3
Format
  • 16
  • 7
Suggested next Filters
35 Produits
ReactivitéHumain
Application IHC, WB
Détails de la commande Cat. No. ABIN630277
$421.86
100 μg
Plus shipping costs $45.00
Envoi sous 9 à 11 jours ouvrables
ReactivitéHumain
Application WB
Détails de la commande Cat. No. ABIN634663
$517.86
50 μg
Plus shipping costs $45.00
Envoi sous 9 à 11 jours ouvrables
ReactivitéHumain, Souris, Porc, Lapin, Rat, Poisson zèbre (Danio rerio)
Application WB
Détails de la commande Cat. No. ABIN2775394
$229.00
100 μL
Plus shipping costs $45.00
Envoi sous 2 à 3 jours ouvrables
ReactivitéHumain
Application IHC (p), WB
Détails de la commande Cat. No. ABIN5575587
$356.00
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain
Application ELISA, WB
Détails de la commande Cat. No. ABIN564490
$440.00
100 μg
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain, Singe
Application IHC, IHC (p), WB
Détails de la commande Cat. No. ABIN203419
$493.17
100 μL
Plus shipping costs $45.00
Envoi sous 11 à 14 jours ouvrables
ReactivitéHumain, Souris, Rat
Application ELISA, IHC (p), WB
Détails de la commande Cat. No. ABIN4901195
$369.83
Plus shipping costs $45.00
Envoi sous 11 à 13 jours ouvrables
Mouse, Monoclonal (16E7), IgG1, kappa, Recombinant Antibody
ReactivitéHumain
Application FACS, IHC
Détails de la commande Cat. No. ABIN5668173
$435.60
200 μg
Plus shipping costs $45.00
Envoi sous 7 à 11 jours ouvrables
Rabbit, Chimeric (16E7), IgG, kappa, Recombinant Antibody
ReactivitéHumain
Application FACS, IHC
Détails de la commande Cat. No. ABIN5668174
$435.60
200 μg
Plus shipping costs $45.00
Envoi sous 7 à 11 jours ouvrables
ReactivitéCheval, Humain, Porc
Application WB
Détails de la commande Cat. No. ABIN2775566
$229.00
100 μL
Plus shipping costs $45.00
Envoi sous 2 à 3 jours ouvrables
ReactivitéHumain, Porc
Application WB
Détails de la commande Cat. No. ABIN2775392
$229.00
100 μL
Plus shipping costs $45.00
Envoi sous 2 à 3 jours ouvrables
ReactivitéHumain, Porc
Application IHC, WB
Détails de la commande Cat. No. ABIN2775393
$229.00
100 μL
Plus shipping costs $45.00
Envoi sous 2 à 3 jours ouvrables
ReactivitéHumain
Application ICC, IHC, WB
Détails de la commande Cat. No. ABIN1858422
$232.00
Plus shipping costs $45.00
Envoi sous 13 à 16 jours ouvrables
ReactivitéHumain
Application ELISA, WB
Détails de la commande Cat. No. ABIN564489
$305.71
50 μL
Plus shipping costs $45.00
Envoi sous 11 à 12 jours ouvrables
ReactivitéHumain, Souris
Application WB
Détails de la commande Cat. No. ABIN3222847
$487.50
200 μL
Plus shipping costs $45.00
Envoi sous 13 à 14 jours ouvrables
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C-Type Lectin Domain Family 4, Member M (CLEC4M) profil antigène

Profil protéine

This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835\; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.

Gene names and symbols associated with CLEC4M

  • C-type lectin domain family 4 member M (CLEC4M) anticorps
  • CD209B anticorps
  • CD209L anticorps
  • CD299 anticorps
  • DC-SIGN2 anticorps
  • DC-SIGNR anticorps
  • DCSIGNR anticorps
  • HP10347 anticorps
  • L-SIGN anticorps
  • LSIGN anticorps

Protein level used designations for CLEC4M

C-type lectin domain family 4 member M , CD209 antigen-like protein 1 , CD299 antigen , DC-SIGN-related protein , dendritic cell-specific ICAM-3-grabbing non-integrin 2 , liver/lymph node-specific ICAM-3 grabbing non-integrin , liver/lymph node-specific ICAM-3-grabbing non-integrin , mannose binding C-type lectin DC-SIGNR , CD209b antigen

GENE ID SPECIES
10332 Homo sapiens
455661 Pan troglodytes