CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) Kits ELISA

CTCF is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. De plus, nous expédions CTCF Anticorps (109) et CTCF Protéines (7) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CTCF 13018 Q61164
CTCF 10664 P49711
CTCF 83726 Q9R1D1
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Top CTCF Kits ELISA sur

Showing 4 out of 11 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests 15 to 18 Days
  96 Tests 2 to 3 Days
  96 Tests 11 to 18 Days
  96 Tests 15 to 18 Days

Plus Kits ELISA pour CTCF partenaires d'interaction

Zebrafish CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. We propose that cohesin and CTCF have distinct functions in the regulation of runx1 during zebrafish embryogenesis.

  2. Data conclude that CTCF modulates MRF functional interactions in the orchestration of myogenesis.

Mouse (Murine) CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. These findings elucidate the role of intra- megabase-scale Topologically Associating Domains cohesin-and-CTCF binding in nuclear organization associated with widespread insulation of distal enhancer activity.

  2. Our findings suggest that inflammation and dysfunctional neuron-microglia interactions are factors in the pathology of CTCF deficiency

  3. Loss of CTCF expression is associated with endothelial dysfunction and embryonic lethality .

  4. The results suggest that CTCF plays an essential role in maintaining hair cells and hearing function in mammalian cochlea.

  5. Data suggest that CTCF sites are porous borders, allowing a super-enhancer to activate a secondary target. Likewise, CTCF sites shield a widely expressed gene from suppressive influences of a silent locus.

  6. maintains the germinal center transcriptional programme, allows a high proliferation rate, and represses the expression of Blimp-1, the master regulator of plasma cell differentiation

  7. Dxz4 represents a structural platform for frequent long-range contacts with multiple loci in a direction dictated by the orientation of its bank of CTCF motifs, which may work as a ratchet to form the distinctive bipartite structure of the condensed inactive X chromosome

  8. neither the deletion of the CTCF locus nor the ectopic insertion of Firre cDNA or its ectopic expression are sufficient to alter topologically associated domains in a sex-specific or allele-specific manner

  9. CTCF maintains regulatory homeostasis of cancer pathways.

  10. CTCF plays an essential role in otic neurogenesis by modulating histone modification in the Neurog1 locus.

  11. CTCF and BORIS cooperate with additional Testis-specific transcriptional regulators to regulate gene expression in developing male gametes.

  12. CCCTC-binding factor CTCF supports the homeostatic maintenance of hematopoietic stem cell (HSCs) pools by sustaining HSC quiescence in a reactive oxygen species ROS-dependent manner.

  13. Authors show that mice devoid of an inducible CTCF binding element, located in the alpha constant gene, display a marked isotype-specific increase of GL transcription in developing and resting splenic B cells and altered CSR in activated B cells.

  14. The study provides evidence that CTCF regulates chromatin organization during spermiogenesis, contributing to the functional organization of mature sperm.

  15. CTCF Binding Sites in the Herpes Simplex Virus 1 Genome Display Site-Specific CTCF Occupation, Protein Recruitment, and Insulator Function.

  16. Both LDB1 and CTCF are required for enhancer-Car2 looping, and the domain of LDB1 contacted by CTCF is necessary to rescue Car2 transcription in LDB1-deficient cells.

  17. CTCF physically associates with Wdr5 and further transcriptionally controls its expression by directly targeting the Wdr5 gene promoter.

  18. Since CTCF and cohesin are required for loop domain formation, our results suggest that chromatin loops are dynamic and frequently break and reform throughout the cell cycle.

  19. Nearly half of all DNase hypersensitivity sites (both constitutive and dynamic) overlap binding events of the bone-essential RUNX2 and/or the chromatin-related CTCF transcription factors.

  20. Chromatin immunoprecipitation-DNA sequence analysis was performed in adult cerebellum and Wiz peaks were found at promoters and transcription factor CTCF binding sites.

Human CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. the CTCF boundary constrains the normal gene-expression program, as well as plays a role in maintaining the oncogenic transcription program for leukemic transformation. The CTCF boundaries may serve as novel therapeutic targets for the treatment of myeloid malignancies.

  2. These phenotypes were rescued with human CTCF mRNA injections.

  3. One of the newly validated CTCF interactors is BRG1, the major ATPase subunit of the chromatin remodeling complex SWI/SNF, establishing a relationship between two master regulators of genome organization.

  4. HTLV-1 disrupts host chromatin structure by forming loops between the provirus and the host genome; certain loops depend on the critical chromatin architectural protein CTCF, which binds to the HTLV-1 provirus.

  5. These findings suggest that as a risk-associated lncRNA, FOXD3-AS1 inhibits the progression of NB through repressing PARP1-mediated CTCF activation.

  6. Enhanced CTCF enrichment was detected on the intergenic sequence XL9 separating two subregions coding for MHC-II genes in septic patients.

  7. prostate cancer risk-associated CTCF sites involved in long-range chromatin loops, were identified.

  8. This study contributes to a better understanding about the underlying principles of CTCF-mediated chromatin interactions and their impact on gene expression.

  9. The authors propose that cellular CCCTC-binding factor binding at the herpes simplex virus 1 CCCTC-binding factor binding sites (CTRL2) acts as a chromatin insulator to keep viral chromatin in a form that is poised for reactivation, a state which we call poised latency.

  10. neither the deletion of the CTCF locus nor the ectopic insertion of Firre cDNA or its ectopic expression are sufficient to alter topologically associated domains in a sex-specific or allele-specific manner

  11. CTCF maintains regulatory homeostasis of cancer pathways.

  12. these results suggest that CTCF participate in DNA damage response via poly(ADP-ribosylation).

  13. Studies suggest that the connection between DNA-binding protein CTCF (CTCF), cohesin, chromatin structure, and behavior is important in understanding of the development of behavior in general, and neurodevelopmental disorders in particular [Review].

  14. ID1, CTCF and ELK1 may be associated with prostate cancer, and may be potential therapeutic targets for the treatment of this disease.

  15. CTCF promotes HSV-1 lytic transcription by facilitating the elongation of RNA Pol II and preventing silenced chromatin on the viral genome.

  16. These results, together with a prior exomesequencing based study, suggest that CTCF mutations may be involved in the development of ovarian endometriosis.

  17. findings establish for the first time that CTCF is an important regulator of the homologous recombination repair pathway.

  18. Findings indicate that CCCTC-binding factor (CTCF)-driven doublesex and mab-3 related transcription factor 2 protein (TERRA) transcription acts in cis to facilitate telomere repeat replication and chromosome stability.

  19. poly(ADP-ribosyl)ated CTCF changes its DNA binding and localisation in a breast cell line which is associated with nucleosome repositioning.

  20. Here, we show that PARP1 and host insulator protein CTCF colocalize at specific sites throughout the EBV genome and provide evidence to suggest that PARP1 acts to stabilize CTCF binding and maintain the open chromatin landscape at the active Cp promoter during type III latency. Further, PARP1 activity is important in maintaining latency type-specific viral gene expression.

CTCF profil antigène

Antigen Summary

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CTCF

  • CCCTC-binding factor (CTCF) anticorps
  • CCCTC-binding factor (zinc finger protein) (ctcf) anticorps
  • CCCTC-binding factor (ctcf) anticorps
  • CCCTC-binding factor (Ctcf) anticorps
  • AW108038 anticorps
  • CTCF anticorps
  • im:7152666 anticorps
  • xctcf anticorps

Protein level used designations for CTCF

transcriptional repressor CTCF , CCCTC-binding factor (zinc finger protein) , transcriptional repressor CTCF-like , 11-zinc finger protein , CTCFL paralog , 11 zinc finger transcriptional repressor

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100101689 Xenopus (Silurana) tropicalis
100224119 Taeniopygia guttata
100350641 Oryctolagus cuniculus
100465401 Ailuropoda melanoleuca
13018 Mus musculus
10664 Homo sapiens
396274 Gallus gallus
479684 Canis lupus familiaris
517097 Bos taurus
83726 Rattus norvegicus
100623274 Sus scrofa
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