CCHC-Type Zinc Finger, Nucleic Acid Binding Protein Protéines (CNBP)

CNBP encodes a nucleic-acid binding protein with seven zinc-finger domains. De plus, nous expédions CNBP Anticorps (104) et CNBP Kits (3) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
CNBP 7555 P62633
CNBP 64530 P62634
CNBP 12785 P53996
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Top CNBP Protéines sur anticorps-enligne.fr

Showing 8 out of 12 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$547.80
Détails
Escherichia coli (E. coli) Humain His-SUMO Tag 100 μg Connectez-vous pour afficher 11 Days
$411.40
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,388.83
Détails
Levure Poulet His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,398.00
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,410.83
Détails

CNBP Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, , ,
Rat (Rattus)

Mouse (Murine)

CNBP Protéines mieux référencés

  1. Human CNBP Protein expressed in Wheat germ - ABIN1349806 : Raheem, Olufemi, Bachinski, Vihola, Sirito, Holmlund-Hampf, Haapasalo, Li, Udd, Krahe: Mutant (CCTG)n expansion causes abnormal expression of zinc finger protein 9 (ZNF9) in myotonic dystrophy type 2. dans The American journal of pathology 2010 (PubMed)

Plus protéines pour CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP) partenaires d'interaction

Human CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP) interaction partners

  1. The authors report a previously unknown long noncoding RNA which, together with CNBP, is involved in the fine-tuned regulation of CCND1 (Montrer CCND1 Protéines) mRNA stability, without which CCND1 (Montrer CCND1 Protéines) exhibits, at most, partial expression.

  2. [CCTG (Montrer CCT3 Protéines)]n repeat expansion, differently from the DM1 (Montrer DMPK Protéines) mutation, does not influence the methylation status of the CNBP gene and other molecular mechanisms are involved in the pathogenesis of Myotonic Dystrophy type 2..

  3. RNA sequence preferences of unconventional RNA-binding proteins, Nudt21 (Montrer NUDT21 Protéines) and CNBP, has been described.

  4. A second point is that DM mutations, although located in noncoding regions, may reduce the expression of mutant alleles, raising questions whether loss-of-function may contribute to the phenotype, or possibly impose a safety limit on knockdown therapies that create or aggravate a DMPK (Montrer DMPK Protéines) or CNBP deficiency state

  5. CNBP is supporting translation by resolving stable structures on mRNAs.

  6. A G-rich motif in the lncRNA Braveheart interacts with Cnbp to specify the cardiovascular lineage.

  7. The cnbp overexpression rescued the Treacher Collins Syndrome phenotype in a dose-dependent manner by a reactive oxygen species-cytoprotective action that prevented the redox-responsive genes' upregulation but did not normalize the synthesis of ribosomal RNAs.

  8. High CNBP expression is associated with Medulloblastoma.

  9. CNBP overexpression caused increase of cell death and suppression of cell metastasis through its induction of G-quadruplex formation in the promoter of hnRNP K (Montrer HNRNPK Protéines) resulting in hnRNP K (Montrer HNRNPK Protéines) down-regulation

  10. Arginine methylation of CNBP in the RG motif does not change the subcellular localization but regulates its RNA binding activity.

Mouse (Murine) CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP) interaction partners

  1. our study suggests that CNBP could maintain testicular development by inhibiting the Wnt (Montrer WNT2 Protéines)/beta-catenin (Montrer CTNNB1 Protéines) pathway, particularly by influencing Sertoli cells.

  2. A G-rich motif in the lncRNA Braveheart interacts with Cnbp to specify the cardiovascular lineage.

  3. data support a role for CNBP as a critical transcription factor and a key regulator of the prolonged expression of sustained cytokine IL-6 (Montrer IL6 Protéines) during persistent LPS (Montrer TLR4 Protéines) stimulation or Gram-negative bacterial infection

  4. CNBP up-regulates tbx2b and smarca5 (Montrer SMARCA5 Protéines), and down-regulates wnt5b (Montrer WNT5B Protéines) gene expression.

  5. expression of APP (Montrer APP Protéines)(Swe) in murine tissue induces a decrease in CNBP expression.

  6. CNBP targets Myc (Montrer MYC Protéines) in rostral head formation, is essential for forebrain induction and specification.

Profil protéine CNBP

Profil protéine

This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CNBP

  • cellular nucleic acid-binding protein (ANI_1_1316064)
  • cellular nucleic acid-binding protein (AOR_1_1792194)
  • cellular nucleic acid-binding protein (PTRG_02341)
  • cellular nucleic acid-binding protein (PTRG_04792)
  • zinc finger protein Byr3 (SJAG_02043)
  • cellular nucleic acid-binding protein (VDBG_00279)
  • cellular nucleic acid-binding protein (VDBG_00590)
  • CCHC-type zinc finger nucleic acid binding protein (CNBP)
  • CCHC-type zinc finger, nucleic acid binding protein (Cnbp)
  • CCHC-type zinc finger nucleic acid binding protein L homeolog (cnbp.L)
  • cellular nucleic acid binding protein (Cnbp)
  • AA408710 Protéine
  • An07g10270 Protéine
  • cnbp1 Protéine
  • cnbpa Protéine
  • dm2 Protéine
  • promm Protéine
  • rnf163 Protéine
  • xcnbp Protéine
  • zcchc22 Protéine
  • znf9 Protéine

Protein level used designations for CNBP

cellular nucleic acid-binding protein , zinc finger protein 9 , cellular nucleic acid binding protein , erythroid differentiation-related , sterol regulatory element-binding protein , zinc finger protein 273 , zinc finger protein 9 (a cellular retroviral nucleic acid binding protein) , cellular nucleic acid binding protein 1 , cellular nucleic acid binding protein a , DNA binding protein

GENE ID SPECIES
4982296 Aspergillus niger CBS 513.88
5988418 Aspergillus oryzae RIB40
6340586 Pyrenophora tritici-repentis Pt-1C-BFP
6343034 Pyrenophora tritici-repentis Pt-1C-BFP
7047891 Schizosaccharomyces japonicus yFS275
9528787 Verticillium alfalfae VaMs.102
9534044 Verticillium alfalfae VaMs.102
100173703 Pongo abelii
7555 Homo sapiens
64530 Rattus norvegicus
476518 Canis lupus familiaris
399294 Xenopus laevis
504831 Bos taurus
395731 Gallus gallus
12785 Mus musculus
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