Profil protéine

CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.

Gene names and symbols associated with CD160 Molecule Protéines (CD160)

• CD160 molecule (CD160) anticorps
• CD160 molecule (Cd160) anticorps
• CD160 antigen (Cd160) anticorps

• AU045688 anticorps
• By55 anticorps
• CD160 anticorps
• NK1 anticorps
• NK28 anticorps
• Afficher tous les alias de synonymes
• RGD1563598 anticorps

Protein level used designations for CD160 Molecule Protéines (CD160)

CD160 molecule , CD160 antigen , natural killer cell BY55 , natural killer cell receptor BY55 , CD160 transmembrane isoform , CD160-delta Ig , natural killer cell receptor, immunoglobulin superfamily member