CD3 Protéines (CD3)

The CD3 complex mediates signal transduction (By similarity). De plus, nous expédions CD3 Anticorps (1210) et CD3 Kits (27) et beaucoup plus de produits pour cette protéine.

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Souris CD3 CD3 12501 P22646
CD3    
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Showing 1 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 11 Days
$888.80
Détails

CD3 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human
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Plus protéines pour CD3 partenaires d'interaction

Pig (Porcine) CD3 interaction partners

  1. expressed and refolded porcine CD3 ectodomain molecules include CD3epsilon, CD3gamma, CD3delta, CD3epsilongamma heterodimer, CD3epsilondelta heterodimer, CD3epsilongamma single-chain fusion protein and CD3epsilondelta single-chain fusion protein

Mouse (Murine) CD3 interaction partners

  1. The data show that CD3epsilon chain couples to Cbl via simultaneous binding of both proteins to Numb, thus mediating TCR degradation

  2. IL-17-producing CD3(bright) gammadelta T cells responded promptly and strongly to pneumococcal infection and during skin inflammation.

  3. these results suggest that CD3zeta can be degraded by two pathways: SLAP/c-Cbl, which targets internalized cell surface CD3zeta dependent on TCR signaling, and LAPTM5, which targets intracellular CD3zeta independent of TCR signaling.

  4. these results indicate that membrane association of the CD3epsilon signaling domain is required for optimal thymocyte development and peripheral T cell function.

  5. These results suggest that proteasome-mediated degradation is involved in hypophosphorylated LAT and PLCgamma1 in Dow2-induced anergic T cells. The novel CD3-specific Ab, Dow2, may provide us with a unique tool for inducing immunosuppression

  6. that Nck recruitment to the TCR is fundamental to mount an efficient T cell response in vivo, and that the Nck-CD3epsilon interaction may represent a target for pharmacological modulation of the immune response.

  7. Structure of murine CD3epsilon complexed with the mitogenic anti-CD3epsilon antibody 2C11 enabled structural comparisons of antibody-liganded and unliganded forms of CD3epsilon revealing that antibody binding does not induce any substantial rearrangements within CD3epsilon.

  8. CFTR dysfunction in T cells can lead directly to aberrant immune responses in CD3+ lymphocytes

  9. analysis of the transgenic integration site in immunodeficient tgepsilon26 human CD3epsilon transgenic mice

  10. Polymorphisms of the CD3varepsilon ectodomain exist in mice,some of which lead to amino acid substitutions which cause structural changes and affect anti-CD3 antibody binding.

  11. the stalks of the CD3 proteins may be critical in transmitting part of the activation signal directly through the membrane.

  12. Results suggest that generation of CD3varepsilon chain isoforms with different N-terminal sequence and pI is a general phenomenon.

  13. We demonstrate that the intra-cytoplasmic (IC) domain of CD3epsilon plays a critical role in regulating TCR expression on DP thymocytes.

  14. activation of tumor reactive CD4+ cells with anti-CD3/anti-CD28 monoclonal antibodies

  15. inability of Nck to bind to the CD3epsilon proline-rich sequence in thymocytes after TCR ligation

  16. That CD43 costimulation was responsible for elevated cytokine/chemokine activity was confirmed at the transcriptional level by real-time PCR for IFN-gamma and CCL5, and by ELISA for IFN-gamma.

  17. insulin-specific Tregs producing IL-10, TGF-beta, and IL-4 are enhanced by suppression of CD3epsilon in a mouse model of autoimmune diabetes

  18. GRK2 is primarily involved in arresting G protein-coupled receptor signals, its interaction with CD3 epsilon may provide a novel means whereby the TCR can negatively regulate signals generated through G protein-coupled receptors.

  19. FcgammaRIIB, a low-affinity immunoglobulin G Fc receptor, and CD3 are involved in cerebellar functions.

  20. CD3epsilon-mediated signal transduction pathway is essential for this transformation process

Profil protéine CD3

Profil protéine

The CD3 complex mediates signal transduction.

Gene names and symbols associated with CD3 Protéines (CD3)

  • CD3e molecule (CD3E)
  • CD3d molecule (CD3D)
  • CD3 antigen, epsilon polypeptide (Cd3e)
  • CD3g molecule S homeolog (cd3g.S)
  • AI504783 Protéine
  • CD3 Protéine
  • cd3-gamma Protéine
  • CD3epsilon Protéine
  • cd3g Protéine
  • cd3g-a Protéine
  • cd3g/d Protéine
  • cd3gd Protéine
  • T3e Protéine
  • t3g Protéine

Protein level used designations for CD3 Protéines (CD3)

CD3 epsilon subunit , T-cell surface glycoprotein CD3 epsilon chain , CD3 glycoprotein , CD3 type I transmembrane glycoprotein , CD3D antigen delta , CD3D antigen, delta polypeptide (TiT3 complex) , T-cell surface glycoprotein CD3 delta chain , T-cell surface protein , T-cell surface antigen T3/Leu-4 epsilon chain , CD3 molecule, gamma/delta (CD3-TCR complex) , CD3g molecule S homeolog , CD3g molecule, gamma (CD3-TCR complex) , CD3gamma/delta , T-cell surface glycoprotein CD3 gamma/delta chain homolog

GENE ID SPECIES
397455 Sus scrofa
396518 Gallus gallus
12501 Mus musculus
373582 Xenopus laevis
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