CD58 Molecule Protéines (CD58)

CD58 encodes a member of the immunoglobulin superfamily. De plus, nous expédions CD58 Anticorps (232) et CD58 Kits (40) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
CD58 965 P19256
CD58    
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Showing 10 out of 21 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Détails
HEK-293 Cells Humain His tag 50 μg 2 to 3 Days
$615.00
Détails
Human Cells Humain Fc Tag 100 μg 14 to 16 Days
$505.35
Détails
Human Cells Cynomolgus His tag 100 μg 14 to 16 Days
$440.65
Détails
Escherichia coli (E. coli) Humain His tag 100 μg 13 to 16 Days
$553.85
Détails
Baculovirus infected Insect Cells Humain His tag 50 μg 13 to 16 Days
$553.85
Détails
Human Cells Humain His tag 100 μg 14 to 16 Days
$440.65
Détails
Wheat germ Humain GST tag 10 μg 11 to 12 Days
$340.00
Détails
Human Cells Humain Fc Tag   10 μg 15 to 16 Days
$212.50
Détails
HEK-293 Cells Humain His tag Human CD58, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg 11 Days
$308.00
Détails

CD58 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , , , , ,
, , , , ,
Cynomolgus

Plus protéines pour CD58 Molecule (CD58) partenaires d'interaction

Human CD58 Molecule (CD58) interaction partners

  1. We show that the Alu insertion promotes skipping of CD58 exon 3 and results in a frameshifted transcript, indicating that the Alu may be the causative variant for increased MS risk at this locus. Using RT-PCR analysis at the endogenous locus, we confirm that the Alu variant is a sQTL for CD58.

  2. SNP rs1335532 associated with multiple sclerosis is located in active CD58 enhancer region and creates a strong functional Ascl2-binding site.

  3. Across different global populations and data sets, carriers of the multiple sclerosis risk allele showed reduced CD58 mRNA levels but increased hsa-miR-548ac levels.

  4. indicate that including both CD58 and CD81 markers in addition to CD19, CD34, CD20, CD38, and CD10 are helpful in minimal residual disease detection by flow cytometry

  5. Mutations and copy number loss of CD58 or TP53 are identified to be an independent negative prognostic factors for diffuse large B cell lymphoma.

  6. A new neuromyelitis optica spectrum disorders susceptibility variant was identified, rs56302466, on the CD58 gene, in a Han Chinese population.

  7. data suggest that loss of CD58 is a potential immune escape mechanism of HL tumor cells, especially in clinically aggressive disease

  8. Cytometry analysis evidenced a specific expression profile on reticulocytes of SCA infants, with notably an increased expression of the adhesion molecules Lu/BCAM, ICAM-4 and LFA-3, both in percentage of positive cells and in surface density.

  9. Frequent inactivating mutations of CD58 in classical Hodgkin lymphoma cell lines, but their rare occurrence in primary Hodgkin and Reed/Sternberg cells.

  10. the fundamental mechanism of glycosylation of human CD2 is to promote CD2-CD58 binding by conformational adjustment of CD2

  11. CD58/CD2 is the primary costimulatory pathway in human CD28-CD8+ T cells.

  12. SNPs in CD58 are associated with increased risk of candidemia.

  13. This study demonstrated that the Polymorphism, Single Nucleotide of CD58 is associated with multiple sclerosis in man in Russia.

  14. Results indicate that CD58 is a novel cell-surface marker that functionally regulates self-renewal of Colorectal tumor-initiating cells.

  15. Linkage disequilibrium show evidence that mir-548ac rs1414273 variant is strongly associated with Multiple sclerosis (MS)-associated haplotype and confirms the single nucleotide polymorphisms within the first intron of CD58 been related too. [review]

  16. The positive correlation is established between content of polymorphic nuclear monocytes and level of expression of molecules of LFA-1, ICAM-1, LFA-3, and PECAM-1.

  17. Genetic variations in CD58 were associated with the susceptibility of neuromyelitis optica in a Korean population.

  18. In 21 percent of diffuse large B cell lymphoma cases, lesions involve the CD58 gene, which encodes a molecule involved in T and natural killer cell-mediated responses

  19. Two large cohorts of systemic sclerosis (SSc) patients of European Caucasian ancestry do not support the implication of ITGAM, ITGAX, and CD58 genes in the genetic susceptibility of SSc, although they were identified as autoimmune disease risk genes.

  20. Seven selected CD58 single-nucleotide polymorphisms were found to not affect aspirin-exacerbated respiratory disease susceptibility in a Korean population.

Pig (Porcine) CD58 Molecule (CD58) interaction partners

  1. immunoaffinity purification of a cell surface protein of relative molecular mass (Mr)=45,000 containing N-linked carbohydrate chains using a novel monoclonal antibody

Profil protéine CD58

Profil protéine

This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with CD58 Molecule Protéines (CD58)

  • CD58 molecule (CD58)
  • ag3 Protéine
  • LFA-3 Protéine
  • LFA3 Protéine

Protein level used designations for CD58 Molecule Protéines (CD58)

CD58 antigen, (lymphocyte function-associated antigen 3) , lymphocyte function-associated antigen 3 , surface glycoprotein LFA-3 , CD58 antigen

GENE ID SPECIES
965 Homo sapiens
396702 Sus scrofa
782186 Bos taurus
101106474 Ovis aries
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