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Activates p53/TP53 by CDKN2A-dependent and CDKN2A- independent pathways (By similarity).. De plus, nous expédions CDKN2A Interacting Protein Protéines (7) et CDKN2A Interacting Protein Kits (3) et beaucoup plus de produits pour cette protéine.
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Oncogenic functions of CARF in hepatocellular carcinoma tumorigenesis is a result of activation of beta-catenin (Montrer CTNNB1 Anticorps)/TCF (Montrer HNF4A Anticorps) signaling.
CARF promotes carcinogenesis in p53 (Montrer TP53 Anticorps)-deficient cells by repressing p21WAF1 and promoting cell cycle progression.
The results suggest that CARF regulates early steps of pre-rRNA processing during ribosome biogenesis by controlling spatial distribution of XRN2 (Montrer XRN2 Anticorps) between the nucleoplasm and nucleolus.
CARF regulates proliferative fate of human cells by dose-dependent regulation of DNA damage signaling.
Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66 (Montrer WDR66 Anticorps), USP20 (Montrer USP20 Anticorps) and OR7C2 (Montrer OR7C2 Anticorps) in a Korean population.
CARF knockdown elicited DNA damage response as evidenced by increased levels of phosphorylated ATM (Montrer ATM Anticorps) and gammaH2AX (Montrer H2AFX Anticorps), leading to induction of mitotic arrest and eventual apoptosis.
CARF may act as a novel key regulator of the p53 (Montrer TP53 Anticorps) pathway at multiple checkpoints
cooperates with human p14ARF in activating p53 (Montrer TP53 Anticorps)
CARF may exert a vital control on p53 (Montrer TP53 Anticorps)-HDM2-p21(WAF1 (Montrer CDKN1A Anticorps)) pathway that is central to the cell cycle control, senescence, and DNA damage response of human cells
CARF exerts a vital control on the p53 (Montrer TP53 Anticorps)-HDM2-p21WAF1 pathway that is frequently altered in cancer cells.
Activates p53/TP53 by CDKN2A-dependent and CDKN2A- independent pathways (By similarity).
, collaborates/cooperates with ARF (alternate reading frame) protein
, collaborator of ARF
, CDKN2A interacting protein
, protein CDKN2AIP homolog A