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CMTM1 belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. De plus, nous expédions CKLF-Like MARVEL Transmembrane Domain Containing 1 Protéines (3) et beaucoup plus de produits pour cette protéine.
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High CMTM1_v17 expression was associated with chemotherapy resistance in lung cancer.
CMTM1 and 3 are priority targets in glioblastomas. First insights into signalling of these two genes that might be conveyed by growth factor receptor, Src family kinase and WNT activation was presented.
Study shows that CMTM1_v17 is highly expressed in human testis and many human tumor tissues and cell lines and seems to enhance cell proliferation and resistance to tumor necrosis factor-alpha (TNF-alpha)-induced apoptosis in MDA-MB-231 breast cancer cells.
Bioinformatics based on CKLF2 cDNA and protein sequences in combination with experimental validation identified CKLFSF1-8 gene clusters, between the SCY and the TM4SF gene families. The 8 family members were cloned and characterized.
gene structure, mapping to chromsome 16, identification of altenative transcription start sites, expression in spermatocyte and testes
novel evidence that the final intron/exon region of the CKLFSF1 gene contains a novel eukaryotic promoter capable of directing expression of the downstream gene, CKLFSF2
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).
CKLF-like MARVEL transmembrane domain-containing protein 1
, chemokine-like factor super family 1
, chemokine-like factor superfamily 1
, chemokine-like factor superfamily member 1
, chemokine-like factor-like protein CKLFH1