CMP-Sialic Acid Transporter Protéines (CMPST)

The protein encoded by CMPST is found in the membrane of the Golgi apparatus, where it transports nucleotide sugars into the Golgi. De plus, nous expédions CMP-Sialic Acid Transporter Anticorps (6) et CMP-Sialic Acid Transporter Kits (4) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
CMPST 24060 Q61420
CMPST 10559 P78382
Rat CMPST CMPST 313139  
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Showing 3 out of 3 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 50 to 55 Days
$7,626.01
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Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 11 to 12 Days
$338.33
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CMPST Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)

Human ,
,

Plus protéines pour CMP-Sialic Acid Transporter (CMPST) partenaires d'interaction

Mouse (Murine) CMP-Sialic Acid Transporter (CMPST) interaction partners

  1. CMP-sialic acid transporter is localized in the medial-trans Golgi

  2. analysis of the functional murine CMP-sialic acid transporter expressed in the E. coli inner membrane

Human CMP-Sialic Acid Transporter (CMPST) interaction partners

  1. We performed exome sequencing on an individual with a profound neurological presentation and identified rare compound heterozygous mutations, p.Thr156Arg and p.Glu196Lys, in the CMP-sialic acid transporter, SLC35A1. Patient primary fibroblasts and serum showed a considerable decrease in the amount of N- and O-glycans terminating in sialic acid

  2. the SLC35A1 generates additional isoforms through alternative splicing.

  3. SLC35A1-deficient cells lack of alpha-dystroglycan O-mannosylation, ligand binding and incorporation of sialic acids.

  4. We confirm an autosomal recessive, generalized sialylation defect due to mutations in SLC35A1

  5. this defect is a new type of congenital disorder of glycosylation (CDG) of type IIf affecting the transport of CMP (Montrer MATN1 Protéines)-sialic acid into the Golgi apparatus.

  6. this study, we introduced two critical genes encoding human CMP-N-acetylneuraminic acid synthetase (Montrer CMAS Protéines) and CMP-sialic acid transporter into tobacco suspension-cultured cell to pave a route for sialic biosynthetic pathway.

  7. CMP-sialic acid transporter is localized in the medial-trans Golgi

Profil protéine CMP-Sialic Acid Transporter (CMPST)

Profil protéine

The protein encoded by this gene is found in the membrane of the Golgi apparatus, where it transports nucleotide sugars into the Golgi. One such nucleotide sugar is CMP-sialic acid, which is imported into the Golgi by the encoded protein and subsequently glycosylated. Defects in this gene are a cause of congenital disorder of glycosylation type 2F (CDG2F). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CMPST

  • solute carrier family 35 (CMP-sialic acid transporter), member 1 (Slc35a1)
  • solute carrier family 35 member A1 (Slc35a1)
  • solute carrier family 35 member A1 (SLC35A1)
  • AA408150 Protéine
  • AI314851 Protéine
  • CDG2F Protéine
  • CMP-SA-Tr Protéine
  • CMP-Sia-Tr Protéine
  • CMPST Protéine
  • CST Protéine
  • hCST Protéine

Protein level used designations for CMPST

CMP-SA-Tr , CMP-Sia-Tr , CMP-sialic acid transporter , solute carrier family 35 member A1 , Solute carrier family 35 member A1 , mutated CMP-sialic acid transporter A1 , solute carrier family 35 (CMP-sialic acid transporter), member 1 , solute carrier family 35 (UDP-galactose transporter), member 1

GENE ID SPECIES
24060 Mus musculus
100689322 Cricetulus griseus
10559 Homo sapiens
313139 Rattus norvegicus
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