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May be involved in pre-mRNA splicing. De plus, nous expédions CWC22 Spliceosome-Associated Protein Homolog (S. Cerevisiae) Protéines (3) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal CWC22 Primary Antibody pour IF, WB - ABIN528288
Alexandrov, Colognori, Shu, Steitz: Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay. dans Proceedings of the National Academy of Sciences of the United States of America 2012
The binding mode of CWC22 to eIF4AIII (Montrer EIF4A3 Anticorps) reveals a facet of how MIF4G domains use their versatile structural frameworks to activate or inhibit DEAD-box proteins.
CWC22 connects pre-mRNA splicing and exon junction complex assembly.
The essential splicing factor (Montrer SLU7 Anticorps) CWC22 has acquired functions in exon junction complex assembly and nonsense-mediated decay during evolution from single-celled to complex eukaryotes.
CWC22 escorts the helicase eIF4AIII (Montrer EIF4A3 Anticorps) to spliceosomes and promotes exon junction complex assembly
These findings identify subtle but significant alterations in spliceosome structure and function, including dysregulated Cajal bodies and CWC22 overexpression, in diabetic sensory neurons that offer new ideas regarding diabetic sensory neurodegeneration in polyneuropathy.
Authors have reconstructed the origin and history of a 127-kbp segmental duplication, R2d, in the house mouse (Mus (Montrer TRPV6 Anticorps) musculus). R2d contains a single protein-coding gene, Cwc22 De novo assembly of both the ancestral (R2d1) and the derived (R2d2) copies reveals that they have been subject to nonallelic gene conversion events spanning tens of kilobases.
Study showed major differences in gene copy number in natural populations. CWC22, SFI1 (Montrer SFI1 Anticorps), and HJURP (Montrer HJURP Anticorps) are highly conserved genes with the most copy-number variation. They all exhibit population-specific expansion patterns, perhaps for local adaptations.
May be involved in pre-mRNA splicing.
, lethal (2) SH0931
, nucampholin homolog
, pre-mRNA-splicing factor CWC22 homolog
, functional spliceosome-associated protein b
, Nucampholin homolog