Calpain 5 (CAPN5) Kits ELISA

Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. De plus, nous expédions Calpain 5 Anticorps (47) et Calpain 5 Protéines (9) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CAPN5 726 O15484
CAPN5 12337 O08688
CAPN5 171495 Q8R4C0
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 15 to 18 Days
$910.56
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Rat
  96 Tests Connectez-vous pour afficher 2 to 3 Days
$713.90
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Souris
  96 Tests Connectez-vous pour afficher 11 to 18 Days
$589.86
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Plus Kits ELISA pour Calpain 5 partenaires d'interaction

Human Calpain 5 (CAPN5) interaction partners

  1. We describe a pediatric patient with severe inflammatory vitreoretinopathy accompanied by hearing loss and developmental delay associated with a novel, de novo CAPN5 missense mutation (c.865C>T, p.Arg289Trp) that shows greater hyperactivation of the calpain protease, indicating a genotype-phenotype correlation.

  2. Capn5 may play a role in CNS development, photoreceptor maintenance, and photoreceptor regeneration.

  3. The novel CAPN5 mutation (p.R289W) is responsible for the present autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV) family. The mutant CAPN5 stimulated secretion and cleavage of SLIT2 fragments that may act as a bystander to regulate abnormal RPE cell proliferation for ADNIV.

  4. Our findings reveal a comprehensive CD81 network in human liver cells and show that hepatitis C virus and Plasmodium highjack selective CD81 interactions, including CAPN5 and CBLB for hepatitis C virus, to invade cells.

  5. The relative domain rotation of 60-100 degrees we found for mini-calpain-5 (a non-classical calpain) is significantly greater than the largest rotation previously observed for a classical calpain

  6. CAPN5 localization at the photoreceptor synapse and with mitochondria explains the neural circuitry phenotype in human CAPN5 disease alleles.

  7. A novel CAPN5 (c.750G>T, p.Lys250Asn) missense mutation causes uveitis and neovascular retinal detachment.

  8. CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation

  9. CAPN5 expression can be suppressed by shRNA-based RNA interference

  10. autosomal dominant neovascular inflammatory vitreoretinopathy is due to CAPN5 gain-of-function rather than haploinsufficiency.

  11. Calpain-5 mutations cause autoimmune uveitis, retinal neovascularization, and photoreceptor degeneration.

  12. Results describe the cloning and characterization of rat calpain-5, which is highly homologous to human and mouse sequences.

  13. CAPN5 polymorphisms are associated with a risk of polycystic ovary syndrome.

  14. CAPN5 seems to influence traits related to increased risk for cardiovascular diseases and play a role as a candidate gene for metabolic syndrome

  15. We have found significant interaction between CAPN5 and PPARD genes that reduces risk for obesity in 55%. CAPN5 and PPARD gene products may also interact in vivo.

  16. Data examine possible allelic imbalance in papillary thyroid cancer at EMSY, CAPN5, and PAK1, as candidate genes within 11q13.5-q14 region using a single nucleotide polymorphism-based analysis.

  17. Calpain5 was expressed in endometrial stromal and glandular cells throughout the menstrual cycle and in decidua, and its expression was decreased in both stromal and glandular cells from women with endometriosis compared with that of fertile controls.

Mouse (Murine) Calpain 5 (CAPN5) interaction partners

  1. mRNA in situ hybridization experiments were performed to identify the expression of CAPN5 in the mouse eye and brain

  2. CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation

  3. CAPN5 is found in punctate domains associated with promyelocytic leukemia (PML) protein within the nucleus.

  4. Despite the numerous expression sites of Capn5, the majority of Capn5-null mice were viable and fertile and appeared healthy

  5. calpain-derived Htt fragmentation has a role in Huntington's disease and aberrant activation of calpains may play a role in HD pathogenesis

Pig (Porcine) Calpain 5 (CAPN5) interaction partners

  1. a novel mitochondrial calpain, calpain-5, is localized in the mitochondria of retinal photoreceptor cells

Calpain 5 (CAPN5) profil antigène

Antigen Summary

Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.

Gene names and symbols associated with Calpain 5 (CAPN5) Kits ELISA

  • calpain 5 (CAPN5) anticorps
  • calpain 5 (Capn5) anticorps
  • calpain 5 L homeolog (capn5.L) anticorps
  • calpain 5 (capn5) anticorps
  • calpain 5a (capn5a) anticorps
  • calpain 5 (Bm1_30735) anticorps
  • calpain 5 (Bm1_30740) anticorps
  • calpain 5 (LOAG_10085) anticorps
  • CAPN5 anticorps
  • Htra3 anticorps
  • MGC53448 anticorps
  • MGC89353 anticorps
  • nCL-3 anticorps
  • zgc:153446 anticorps

Protein level used designations for Calpain 5 (CAPN5) Kits ELISA

calpain htra-3 , calpain-5 , new calpain 3 , nCL-3 , high-temperature requirement factor A3 , calpain 5 , calpain-5-like , LOW QUALITY PROTEIN: calpain-5

GENE ID SPECIES
726 Homo sapiens
12337 Mus musculus
171495 Rattus norvegicus
380502 Xenopus laevis
419086 Gallus gallus
448405 Xenopus (Silurana) tropicalis
485175 Canis lupus familiaris
536988 Bos taurus
100394779 Callithrix jacchus
100448228 Pongo abelii
563346 Danio rerio
6101039 Brugia malayi
6101040 Brugia malayi
9947526 Loa loa
100351053 Oryctolagus cuniculus
100524513 Sus scrofa
100714940 Cavia porcellus
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