anti-Carbonic Anhydrase IX (CA9) Anticorps

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. De plus, nous expédions Carbonic Anhydrase IX Kits (59) et Carbonic Anhydrase IX Protéines (25) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CA9 230099 Q8VHB5
CA9 313495  
CA9 768 Q16790
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Top anti-Carbonic Anhydrase IX Anticorps sur anticorps-enligne.fr

Showing 10 out of 316 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Chien Lapin Inconjugué ChIP, ELISA, FACS, GS, ICC, IF, IHC, IHC (fro), IHC (p), SimWes, WB Immunocytochemistry/Immunofluorescence: Carbonic Anhydrase IX/CA9 Antibody [ABIN151877] - Analysis of Biotin conjugate of ABIN151877. Human RCC tumor cryosections using ABIN151877 (Panel A). Panel B shows staining with normal rabbit serum. Simple Western: Carbonic Anhydrase IX/CA9 Antibody [ABIN151877] - Simple Western lane view shows a specific band for CAIX in 0.1 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$516.98
Détails
Chien Lapin Biotin ELISA, ICC, IF, IHC (fro), IHC (p), WB Renal carcinoma tissue stained with polyclonal carbonic anhydrase IX, ABIN151877. Detection of carbonic anhydrase IX in transfected HEK cell lysate using ABIN151877. Rabbit IgG was used as a negative control. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$629.98
Détails
Humain Souris Inconjugué CyTOF, ELISA, FACS, ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Carbonic Anhydrase IX/CA9 Antibody (2D3) [NBP1-51691] - HeLa cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-CA9 (2D3) [NBP1-51691] at a 1:200 dilution overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:500 dilution. Actin was detected with Phalloidin 568 (Red) at a 1:200 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective. Immunohistochemistry-Paraffin: Carbonic Anhydrase IX/CA9 Antibody (2D3) [NBP1-51691] - Immunohistochemical analysis of paraffin-embedded lung tissues (left) and colonic tissues (right) using Carbonic Anhydrase IX mouse mAb with DAB staining. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$446.35
Détails
Humain Souris Inconjugué ELISA, FACS, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 1: Western blot analysis using CA9 mAb against human CA9 recombinant protein. (Expected MW is 42 kDa) Dilution: 1/500 - 1/2000 100 μL Connectez-vous pour afficher 8 to 11 Days
$577.50
Détails
Humain Souris Inconjugué ELISA, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 1: Western blot analysis using CA9 mAb against human CA9 recombinant protein. (Expected MW is 42 kDa) Dilution: 1/500 - 1/2000 100 μL Connectez-vous pour afficher 8 to 11 Days
$577.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of Carbonic Anhydrase 9 expression in HeLa (A), Ramos (B), Molt4 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué FACS, IF, WB Western blot analysis of CA9 antibody (Center) (ABIN390041) in Hela cell line lysates (35 µg/lane). CA9 (arrow) was detected using the purified polyclonal antibody. Flow cytometric analysis of hela cells using CA9 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of CA9/G250:78-89 (ABIN390038) in HepG2 cell line lysates (35 µg/lane). CA9 (arrow) was detected using the purified polyclonal antibody. Anti-CA9 Antibody (N-term) at 1:2000 dilution + SW620 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 50 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:2000 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué WB The anti-CA9 Pab (ABIN390039) is used in Western blot to detect CA9 in Jurkat tissue lysate 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails

anti-Carbonic Anhydrase IX Anticorps mieux référencés

  1. Dog (Canine) Polyclonal CA9 Primary Antibody pour ChIP, ELISA - ABIN151877 : Kaidi, Moorghen, Williams, Paraskeva: Is the downregulation of EphB2 receptor expression during colorectal tumorigenesis due to hypoxia? dans Gut 2007 (PubMed)
    Show all 162 Pubmed References

  2. Dog (Canine) Polyclonal CA9 Primary Antibody pour ELISA, ICC - ABIN251625 : Bui, Seligson, Han, Pantuck, Dorey, Huang, Horvath, Leibovich, Chopra, Liao, Stanbridge, Lerman, Palotie, Figlin, Belldegrun: Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2003 (PubMed)
    Show all 7 Pubmed References

  3. Dog (Canine) Polyclonal CA9 Primary Antibody pour ELISA, IHC (fro) - ABIN251626 : Sathornsumetee, Cao, Marcello, Herndon, McLendon, Desjardins, Friedman, Dewhirst, Vredenburgh, Rich: Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan. dans Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 (PubMed)
    Show all 5 Pubmed References

  4. Polyclonal CA9 Primary Antibody pour IHC (fro), IF - ABIN540761 : Yoo, Baia, Smith, McDermott, Bollen, Vandenberg, Lamborn, Lal: Expression of the hypoxia marker carbonic anhydrase 9 is associated with anaplastic phenotypes in meningiomas. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2007 (PubMed)
    Show all 5 Pubmed References

  5. Human Polyclonal CA9 Primary Antibody pour ELISA, WB - ABIN545603 : Span, Bussink, Manders, Beex, Sweep: Carbonic anhydrase-9 expression levels and prognosis in human breast cancer: association with treatment outcome. dans British journal of cancer 2003 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal CA9 Primary Antibody pour CyTOF, ELISA - ABIN4287748 : Cai, Alshehri, Choksi, Pestronk: Regional ischemic immune myopathy: a paraneoplastic dermatomyopathy. dans Journal of neuropathology and experimental neurology 2014 (PubMed)
    Show all 3 Pubmed References

  7. Human Monoclonal CA9 Primary Antibody pour FACS, ELISA - ABIN1724882 : Pinheiro, Sousa, Albergaria, Paredes, Dufloth, Vieira, Schmitt, Baltazar: GLUT1 and CAIX expression profiles in breast cancer correlate with adverse prognostic factors and MCT1 overexpression. dans Histology and histopathology 2011 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal CA9 Primary Antibody pour IHC, ELISA - ABIN1724883 : Neumeister, Sullivan, Lindner, Lezon-Geyda, Li, Zavada, Martel, Glazer, Tuck, Rimm, Harris: Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer. dans Breast cancer research and treatment 2012 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal CA9 Primary Antibody pour CyTOF, FACS - ABIN4900431 : Swayampakula, McDonald, Vallejo, Coyaud, Chafe, Westerback, Venkateswaran, Shankar, Gao, Laurent, Lou, Bennewith, Supuran, Nabi, Raught, Dedhar: The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion. dans Oncogene 2017 (PubMed)
    Show all 2 Pubmed References

  10. Human Polyclonal CA9 Primary Antibody pour IF (p), IHC (p) - ABIN752773 : Gogiraju, Xu, Bochenek, Steinbrecher, Lehnart, Wenzel, Kessel, Zeisberg, Dobbelstein, Schäfer: Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice. dans Journal of the American Heart Association 2015 (PubMed)

Plus d’anticorps contre Carbonic Anhydrase IX partenaires d’interaction

Mouse (Murine) Carbonic Anhydrase IX (CA9) interaction partners

  1. Authors demonstrate that CAIX associates with MMP14 through potential phosphorylation residues within its intracellular domain, and that CAIX enhances MMP14-mediated collagen degradation by directly contributing hydrogen ions required for MMP14 catalytic activity.

  2. Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors.

  3. constitutive activation of the NF-kappaB pathway in CAIX-depleted cells restored G-CSF secretion

  4. Downregulation of carbonic anhydrase IX promotes Col10a1 expression in chondrocytes.

  5. CA IX may directly or indirectly play novel functions in brain tissue.

  6. about half the CA-dependent muscular lactate flux occurs across the surface membrane, while the other half occurs across the membranes of the T tubuli

  7. Data show that CA9, GLUT1 and LOX mRNA levels were equally and strongly correlated to hypoxic extent in FaDudd, and the same profile was observed for CA9 and GLUT1, but not LOX, in SCCVII tumors.

  8. a novel role for CA IX in the regulation of immunologic processes and digestion

  9. although CA IX-deficiency is not a tumor-promoting factor per se, it induces glandular atrophy in the body mucosa, a lesion which is considered to be a preneoplastic alteration in the stomach

  10. These results suggest that the loss of function of cytosolic CA II in the stomach of Car2-/- mice leads to up-regulation of an extracellular CA, namely CA IX, which is expressed on the cell surface of the gastric epithelium.

  11. CA9 may regulate ion and pH homeostasis within the developing embryo.

  12. CA9 has chaperone-like functions and CA9 shed from tumors may play a direct role in stimulating an adaptive immune response

  13. that expression of CA9 is regulated through both the HIF-1 and unfolded protein response hypoxia response pathways in vitro and in vivo.

Human Carbonic Anhydrase IX (CA9) interaction partners

  1. High membranous CA9 expression is associated with clear cell renal cell carcinoma.

  2. Results find that CAIX expression was increased in soft tissue and associated with worse disease-free survival.

  3. Positive CAIX cytoplasmic expression was significantly associated with lymph node affected and with disease-specific survival in oral squamous cell carcinoma.

  4. we identified an SNP in the CA9 3'UTR as a novel diagnostic and prognostic factor for HCC. The rs1048638-A genotype significantly affects miR-34a targeting and expression levels of CA9. The miR-34a-CA9 axis is important in controlling tumor growth and metastasis of HCC cells.

  5. CAIX and CAXII expression are diagnostic for breast cancer subtype and prognosticators of patient survival. Overall, we show that CAIX but not CAXII drives growth, migration, and metastasis consistent with its expression in more aggressive breast cancers.

  6. Our findings indicated that CA-IX may be a potential prognostic biomarker in the treatment of glioblastoma multiforme

  7. Our results do not suggest a prognostic role for CA IX overexpression in stage III non-small cell lung cancer patients who received neoadjuvant treatment.

  8. FZD1 and CAIX might be important biological markers for the carcinogenesis, metastasis, invasion, and prognosis of pancreatic ductal adenocarcinoma

  9. CAII, CAIX, and CAXII all have characteristic expression patterns in esophageal adenocarcinoma (EAC), its precursors and normal squamous epithelium. In EAC, CAII downregulation is associated with metastatic disease. CAIX expression is lost towards the more malignant lesions, but in lymph node positive disease, expression seems to be higher. CAXII is only expressed in normal esophageal epithelium.

  10. High expression of CA9 is associated with breast cancer.

  11. Data suggest that the conformational flexibility may have several important roles in tumour progression, facilitating interactions of carbonic anhydrase IX (hCA IX) with partner proteins assisting tumour spreading and progression.

  12. the findings of this study establish the SOX9/CA9-mediated oncogenic pathway in glioma, the inhibition of which enhances the sensitivity of glioma cells to Temozolomide (TMZ) treatment, and thus highlights the value of developing small molecules or antibodies against the SOX9/CA9 pathway, for combination therapy with TMZ, in the more efficient management of glioma

  13. CA9 SNP rs1048638 and haplotype A1AA are associated with the susceptibility of cervical invasive squamous cell carcinoma for Taiwanese women

  14. The TCGA data revealed that CAIX expression was significantly higher in bladder cancer specimens than in normal tissue.

  15. CAIX enzyme inhibition assay showed the IC50 values in nM range. Though all the three compounds (1-3) showed a good binding with CAIX, compound 2 showed the best inhibition of CAIX activity. These compounds were non-toxic on normal cell lines (HEK-293) and significantly inhibit the proliferation of hypoxic cancer cells

  16. CA9 expression was observed in normal islets, while neuroendocrine microadenomas and small (< 1 cm) pancreatic neuroendocrine neoplasms/tumors showed CA9 expression loss.

  17. Study revealed that CA9 expression was a pivotal predictive factor for poor prognosis after radical surgery for HCC. Moreover, the CA9 regulation of the expression of EMT-related molecules represented a mechanism that enhanced malignant potential.

  18. Report weak CA9 immunoreactivity in majority of CA9 positive colorectal carcinoma cases associated with macroscopic growth pattern.

  19. Molecular characterization of carbonic anhydrase IX catalytic domain has been presented.

  20. Authors present evidence that enhanced autophagy does not play a role in the enhanced growth of the CA9+ cells. Our study suggests a direct in vivo functional link between hypoxic cells and CICs in primary cervix cancer xenografts.

Carbonic Anhydrase IX (CA9) profil antigène

Profil protéine

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

Gene names and symbols associated with CA9

  • carbonic anhydrase 9 (CA9) anticorps
  • carbonic anhydrase 9 (CAH9) anticorps
  • carbonic anhydrase 9 (Car9) anticorps
  • Ca9 anticorps
  • CAIX anticorps
  • MN anticorps
  • MN/CA9 anticorps

Protein level used designations for CA9

carbonic anhydrase IX , carbonic anhydrase 9 , CA-IX , carbonate dehydratase IX , membrane antigen MN homolog , P54/58N , RCC-associated antigen G250 , RCC-associated protein G250 , carbonic dehydratase , membrane antigen MN , pMW1 , renal cell carcinoma-associated antigen G250

GENE ID SPECIES
473223 Pan troglodytes
511923 Bos taurus
5726457 Chlamydomonas reinhardtii
230099 Mus musculus
313495 Rattus norvegicus
768 Homo sapiens
611933 Canis lupus familiaris
100152792 Sus scrofa
770004 Gallus gallus
100337777 Oryctolagus cuniculus
Fournisseurs de qualité sélectionnés pour anti-Carbonic Anhydrase IX (CA9) Anticorps
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