anti-Carbonic Anhydrase IX (CA9) Anticorps

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. De plus, nous expédions Carbonic Anhydrase IX Kits (58) et Carbonic Anhydrase IX Protéines (25) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CA9 230099 Q8VHB5
CA9 313495  
CA9 768 Q16790
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-Carbonic Anhydrase IX Anticorps sur anticorps-enligne.fr

Showing 10 out of 302 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Chien Lapin Inconjugué ChIP, ELISA, FACS, GS, ICC, IF, IHC, IHC (fro), IHC (p), SimWes, WB Immunocytochemistry/Immunofluorescence: Carbonic Anhydrase IX/CA9 Antibody [ABIN151877] - Analysis of Biotin conjugate of ABIN151877. Human RCC tumor cryosections using ABIN151877 (Panel A). Panel B shows staining with normal rabbit serum. Simple Western: Carbonic Anhydrase IX/CA9 Antibody [ABIN151877] - Simple Western lane view shows a specific band for CAIX in 0.1 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$514.63
Détails
Humain Souris Inconjugué IHC, ELISA, WB 100 μg Connectez-vous pour afficher 2 to 3 Days
$430.10
Détails
Chien Lapin Biotin ELISA, ICC, IF, IHC (fro), IHC (p), WB Renal carcinoma tissue stained with polyclonal carbonic anhydrase IX, ABIN151877. Detection of carbonic anhydrase IX in transfected HEK cell lysate using ABIN151877. Rabbit IgG was used as a negative control. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$626.75
Détails
Humain Souris Inconjugué ELISA, FACS, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 1: Western blot analysis using CA9 mAb against human CA9 recombinant protein. (Expected MW is 42 kDa) Dilution: 1/500 - 1/2000 100 μL Connectez-vous pour afficher 8 to 11 Days
$561.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of Carbonic Anhydrase 9 expression in HeLa (A), Ramos (B), Molt4 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Souris Fluorescein FACS Detection of Carbonic Anhydrase IX/CA9 in U-87 MG Human Cell Line by Flow Cytometry. U-87 MG human glioblastoma/ astrocytoma cell line was stained with Mouse Anti-Human Carbonic Anhydrase IX/CA9 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Connectez-vous pour afficher 8 to 9 Days
$299.00
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Souris Inconjugué CyTOF, ELISA, FACS, ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Carbonic Anhydrase IX/CA9 Antibody (2D3) [NBP1-51691] - HeLa cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-CA9 (2D3) [NBP1-51691] at a 1:200 dilution overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:500 dilution. Actin was detected with Phalloidin 568 (Red) at a 1:200 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective. Immunohistochemistry-Paraffin: Carbonic Anhydrase IX/CA9 Antibody (2D3) [NBP1-51691] - Immunohistochemical analysis of paraffin-embedded lung tissues (left) and colonic tissues (right) using Carbonic Anhydrase IX mouse mAb with DAB staining. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails
Humain Lapin Inconjugué WB Western blot analysis of CA9/G250:78-89 (ABIN390038) in HepG2 cell line lysates (35 µg/lane). CA9 (arrow) was detected using the purified polyclonal antibody. Anti-CA9 Antibody (N-term) at 1:2000 dilution + SW620 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 50 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:2000 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué FACS, IF, WB Western blot analysis of CA9 antibody (Center) (ABIN390041) in Hela cell line lysates (35 µg/lane). CA9 (arrow) was detected using the purified polyclonal antibody. Flow cytometric analysis of hela cells using CA9 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails

CA9 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Mouse (Murine) , , ,
,
,
, , , , , , , , , , , , , , , , , , ,
Rat (Rattus) , , ,
,
,
, , , , , , , , , , , , , , , , , , ,
Human , , , ,
, ,
,
, , , , , , , , , , , , , , , , , , ,

anti-Carbonic Anhydrase IX Anticorps mieux référencés

  1. Dog (Canine) Polyclonal CA9 Primary Antibody pour ChIP, ELISA - ABIN151877 : Kaidi, Moorghen, Williams, Paraskeva: Is the downregulation of EphB2 receptor expression during colorectal tumorigenesis due to hypoxia? dans Gut 2007 (PubMed)
    Show all 144 Pubmed References

  2. Dog (Canine) Polyclonal CA9 Primary Antibody pour ELISA, ICC - ABIN251625 : Bui, Seligson, Han, Pantuck, Dorey, Huang, Horvath, Leibovich, Chopra, Liao, Stanbridge, Lerman, Palotie, Figlin, Belldegrun: Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2003 (PubMed)
    Show all 7 Pubmed References

  3. Dog (Canine) Polyclonal CA9 Primary Antibody pour ELISA, IHC (fro) - ABIN251626 : Sathornsumetee, Cao, Marcello, Herndon, McLendon, Desjardins, Friedman, Dewhirst, Vredenburgh, Rich: Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan. dans Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal CA9 Primary Antibody pour CyTOF, ELISA - ABIN4287748 : Cai, Alshehri, Choksi, Pestronk: Regional ischemic immune myopathy: a paraneoplastic dermatomyopathy. dans Journal of neuropathology and experimental neurology 2014 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal CA9 Primary Antibody pour FACS, ELISA - ABIN1724882 : Pinheiro, Sousa, Albergaria, Paredes, Dufloth, Vieira, Schmitt, Baltazar: GLUT1 and CAIX expression profiles in breast cancer correlate with adverse prognostic factors and MCT1 overexpression. dans Histology and histopathology 2011 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal CA9 Primary Antibody pour IHC, ELISA - ABIN1724883 : Neumeister, Sullivan, Lindner, Lezon-Geyda, Li, Zavada, Martel, Glazer, Tuck, Rimm, Harris: Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer. dans Breast cancer research and treatment 2012 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal CA9 Primary Antibody pour IF (p), IHC (p) - ABIN752773 : Gogiraju, Xu, Bochenek, Steinbrecher, Lehnart, Wenzel, Kessel, Zeisberg, Dobbelstein, Schäfer: Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice. dans Journal of the American Heart Association 2015 (PubMed)

  8. Human Monoclonal CA9 Primary Antibody pour FACS, IHC - ABIN2717028 : Wang, Cheng, Liu, Zhang, Li, Li: CREB is a key negative regulator of carbonic anhydrase IX (CA9) in gastric cancer. dans Cellular signalling 2015 (PubMed)

  9. Human Polyclonal CA9 Primary Antibody pour CyTOF, FACS - ABIN4900431 : Swayampakula, McDonald, Vallejo, Coyaud, Chafe, Westerback, Venkateswaran, Shankar, Gao, Laurent, Lou, Bennewith, Supuran, Nabi, Raught, Dedhar: The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion. dans Oncogene 2017 (PubMed)

  10. Human Monoclonal CA9 Primary Antibody pour FACS - ABIN4897691 : McIntyre, Patiar, Wigfield, Li, Ledaki, Turley, Leek, Snell, Gatter, Sly, Vaughan-Jones, Swietach, Harris: Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2012 (PubMed)

Plus d’anticorps contre Carbonic Anhydrase IX partenaires d’interaction

Mouse (Murine) Carbonic Anhydrase IX (CA9) interaction partners

  1. Authors demonstrate that CAIX associates with MMP14 (Montrer MMP14 Anticorps) through potential phosphorylation residues within its intracellular domain, and that CAIX enhances MMP14 (Montrer MMP14 Anticorps)-mediated collagen degradation by directly contributing hydrogen ions required for MMP14 (Montrer MMP14 Anticorps) catalytic activity.

  2. Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors.

  3. constitutive activation of the NF-kappaB (Montrer NFKB1 Anticorps) pathway in CAIX-depleted cells restored G-CSF (Montrer CSF3 Anticorps) secretion

  4. Downregulation of carbonic anhydrase IX promotes Col10a1 (Montrer COL10A1 Anticorps) expression in chondrocytes.

  5. CA IX may directly or indirectly play novel functions in brain tissue.

  6. Data show that CA9, GLUT1 (Montrer SLC2A1 Anticorps) and LOX (Montrer LOX Anticorps) mRNA levels were equally and strongly correlated to hypoxic extent in FaDudd, and the same profile was observed for CA9 and GLUT1 (Montrer SLC2A1 Anticorps), but not LOX (Montrer LOX Anticorps), in SCCVII tumors.

  7. a novel role for CA IX in the regulation of immunologic processes and digestion

  8. although CA IX-deficiency is not a tumor-promoting factor per se, it induces glandular atrophy in the body mucosa, a lesion which is considered to be a preneoplastic alteration in the stomach

  9. These results suggest that the loss of function of cytosolic CA II (Montrer CA2 Anticorps) in the stomach of Car2 (Montrer CA2 Anticorps)-/- mice leads to up-regulation of an extracellular CA, namely CA IX, which is expressed on the cell surface of the gastric epithelium.

  10. CA9 may regulate ion and pH homeostasis within the developing embryo.

Human Carbonic Anhydrase IX (CA9) interaction partners

  1. The TCGA data revealed that CAIX expression was significantly higher in bladder cancer specimens than in normal tissue.

  2. CAIX enzyme inhibition assay showed the IC50 values in nM range. Though all the three compounds (1-3) showed a good binding with CAIX, compound 2 showed the best inhibition of CAIX activity. These compounds were non-toxic on normal cell lines (HEK (Montrer EPHA3 Anticorps)-293) and significantly inhibit the proliferation of hypoxic cancer cells

  3. CA9 expression was observed in normal islets, while neuroendocrine microadenomas and small (< 1 cm) pancreatic neuroendocrine neoplasms/tumors showed CA9 expression loss.

  4. Study revealed that CA9 expression was a pivotal predictive factor for poor prognosis after radical surgery for HCC (Montrer FAM126A Anticorps). Moreover, the CA9 regulation of the expression of EMT (Montrer ITK Anticorps)-related molecules represented a mechanism that enhanced malignant potential.

  5. Report weak CA9 immunoreactivity in majority of CA9 positive colorectal carcinoma cases associated with macroscopic growth pattern.

  6. Molecular characterization of carbonic anhydrase IX catalytic domain has been presented.

  7. Authors present evidence that enhanced autophagy does not play a role in the enhanced growth of the CA9+ cells. Our study suggests a direct in vivo functional link between hypoxic cells and CICs in primary cervix cancer xenografts.

  8. Genetic disruption of the intracellular pH-regulating proteins Na+/H+ exchanger 1 (SLC9A1 (Montrer SLC9A1 Anticorps)) and carbonic anhydrase 9 reduces the proliferation of colon cancer cells.

  9. combined CA9-/CD147-capture antibodies demonstrated high efficiency for capturing circulating renal cell carcinoma (Montrer MOK Anticorps) cells

  10. Data show that targeting the hypoxic tumor compartment by knockdown of carbonic anhydrase IX (CAIX) using short hairpin RNA or by chemical inhibition of CAIX with acetazolamide potentiates the anti-cancer activity of mTOR (Montrer FRAP1 Anticorps) inhibitors rapamycin.

Carbonic Anhydrase IX (CA9) profil antigène

Profil protéine

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

Gene names and symbols associated with CA9

  • carbonic anhydrase 9 (CA9) anticorps
  • carbonic anhydrase 9 (CAH9) anticorps
  • carbonic anhydrase 9 (Car9) anticorps
  • Ca9 anticorps
  • CAIX anticorps
  • MN anticorps
  • MN/CA9 anticorps

Protein level used designations for CA9

carbonic anhydrase IX , carbonic anhydrase 9 , CA-IX , carbonate dehydratase IX , membrane antigen MN homolog , P54/58N , RCC-associated antigen G250 , RCC-associated protein G250 , carbonic dehydratase , membrane antigen MN , pMW1 , renal cell carcinoma-associated antigen G250

GENE ID SPECIES
473223 Pan troglodytes
511923 Bos taurus
5726457 Chlamydomonas reinhardtii
230099 Mus musculus
313495 Rattus norvegicus
768 Homo sapiens
611933 Canis lupus familiaris
100152792 Sus scrofa
770004 Gallus gallus
100337777 Oryctolagus cuniculus
Fournisseurs de qualité sélectionnés pour anti-Carbonic Anhydrase IX (CA9) Anticorps
Avez-vous cherché autre chose?