Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein Protéines (CTNND2)

CTNND2 encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. De plus, nous expédions Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein Anticorps (61) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
CTNND2 18163 O35927
CTNND2 1501 Q9UQB3
CTNND2 114028  
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
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Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
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Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,684.00
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CTNND2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)

Human ,
,
Rat (Rattus)

Plus protéines pour Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2) partenaires d'interaction

Mouse (Murine) Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2) interaction partners

  1. delta-Catenin Regulates Spine Architecture via Cadherin and PDZ-dependent Interactions.

  2. Results conclude that the introduction of CTNND2 gene variation is an important milestone in prostate cancer metabolic adaptation.

  3. Delta-catenin occurs in mouse brain dendrites along with PSD-95 (Montrer DLG4 Protéines) in postsynaptic scaffolds. It forms stable complexes with glutamate (Montrer GRIN1 Protéines) receptors, suggesting a link between delta-catenin and glutamatergic synaptic transmission during neuronal development.

  4. PS-1 (Montrer PSEN1 Protéines) can affect delta-catenin-induced morphogenesis possibly through the regulation of its processing and stability.

  5. conditional targeting of p120 catenin (Montrer CTNND1 Protéines) in mice leads to progressive development of skin neoplasias associated with intrinsic NF-kappaB (Montrer NFKB1 Protéines) activation.

  6. Acute knockdown of delta-catenin leads to increases in spine and synapse density in hippocampal neurons during development.

Human Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2) interaction partners

  1. Data provide evidence that delta-catenin may serve an important role in the malignancy of lung adenocarcinoma through activation of canonical Wnt (Montrer WNT2 Protéines) signaling and cancer stem cell maintenance.

  2. Gene Ontology analysis revealed that neuronal differentiation-related genes were enriched among targets that were co-regulated by REST and TRIM28 (Montrer TRIM28 Protéines), while the level of CTNND2 was increased by the knockdown of REST and TRIM28 (Montrer TRIM28 Protéines). Consistently, during neuronal differentiation, the level of CTNND2 increased while those of REST and TRIM28 (Montrer TRIM28 Protéines) decreased, suggesting that CTNND2 expression may be co-regulated by both.

  3. We propose CTNND2 as the causal gene infamilial cortical myoclonic tremor and epilepsy-3

  4. At the molecular level, CTNND2 is at the crossroad with interactions to such signaling pathways of Wnt and Rho family small GTPases in the Ras superfamily, which are known to drive human disease pathogenesis.

  5. Our data suggested that genetic variants in GRM6 (Montrer GRM6 Protéines) are associated with high myopia. The mechanism of GRM6 (Montrer GRM6 Protéines) in the development of high myopia need to be further investigated.

  6. Multigenerational autosomal dominant inheritance of 5p chromosomal deletions resulting in Cri-du-Chat Syndrome with SEMA5A, CTNND2, and ICE1 deficiencies has been described.

  7. the effect of CTNND2 polymorphisms on normal variability and identified a polymorphism (rs2561622) with significant effect on phonological ability and white matter volume in the left frontal lobe, was investigated.

  8. Study describes two Ion-syndromic intellectual disability cases, positive for the presence of a small copy number variants, intragenic CTNND2 gene deletion.

  9. Results conclude that the introduction of CTNND2 gene variation is an important milestone in prostate cancer metabolic adaptation.

  10. co-expression of Delta-catenin and RhoA (Montrer RHOA Protéines) was significantly associated with histological type, differentiation, pTNM stage, lymphatic metastasis and a poor prognosis in non-small cell lung cancer

Profil protéine Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2)

Profil protéine

This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome.

Gene names and symbols associated with CTNND2

  • catenin delta 2 (CTNND2)
  • delta-catenin (BACOIKO001_27)
  • catenin delta-2 (LOC100070792)
  • catenin (cadherin associated protein), delta 2 (Ctnnd2)
  • catenin delta 2 (Ctnnd2)
  • catenin (cadherin-associated protein), delta 2b (ctnnd2b)
  • Catnd2 Protéine
  • ctnnd2 Protéine
  • GT24 Protéine
  • neurojugin Protéine
  • NPRAP Protéine
  • si:dkey-40c17.4 Protéine

Protein level used designations for CTNND2

catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) , delta-catenin , catenin delta-2-like , catenin delta 2 , catenin delta-2 , neural plakophilin-related arm-repeat protein , neurojungin , T-cell delta-catenin , catenin (cadherin-associated protein), delta 2

GENE ID SPECIES
420922 Gallus gallus
461724 Pan troglodytes
488048 Canis lupus familiaris
6166784 Oikopleura dioica
100070792 Equus caballus
100406541 Callithrix jacchus
100517978 Sus scrofa
18163 Mus musculus
1501 Homo sapiens
523661 Bos taurus
114028 Rattus norvegicus
558069 Danio rerio
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