anti-Cbl-Interacting Protein Sts-1 (STS1) Anticorps

STS1 encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. De plus, nous expédions Cbl-Interacting Protein Sts-1 Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
STS1 84959 Q8TF42
STS1 72828 Q8BGG7
STS1 315579  
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Top anti-Cbl-Interacting Protein Sts-1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 30 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit <br /> Target Name: Ubash3b <br /> Sample Tissue: Rat Testis lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Chien Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
$619.30
Détails
Humain Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of STS-1 staining in SKOV3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Souris Inconjugué ELISA, IHC, IHC (p), WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$537.17
Détails
Humain Souris Inconjugué IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to UBASH3B on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged UBASH3B is 1 ng/ml as a capture antibody. 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué IHC (p), IHC, WB Immunohistochemistry-Paraffin: UBASH3B/STS1/Tula-2 Antibody [NBP1-32592] - SW480 xenograft. Western Blot: UBASH3B/STS1/Tula-2 Antibody [NBP1-32592] - A:Hep G2. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$514.63
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Souris Lapin Inconjugué ELISA, WB Western blot using  Affinity Purified anti-Sts-1 antibody shows detection of a band ~70 kDa corresponding to mouse Sts-1. Approximately 1.0 ?g of recombinant (truncated) Sts-1-GST was separated by SDS-PAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 0.3?ug/ml overnight at 4° C followed by washes and reaction with a 1:10,000 dilution of IRDye800 conjugated Gt-a-Rabbit IgG [H&L] MX . IRDye800 fluorescence image was captured using the Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results. Immunohistochemistry with anti-Sts-1 antibody showing Sts-1 staining of histiocytic elements in cytoplasm of human tonsil at 20x and 40x (B & C). Formalin fixed/paraffin embedded sections were subjected to heat induced epitope retrieval (HIER) at pH 6.2 and then incubated with rabbit anti-Sts-1 antibody at 4.0 µg/ml for 60 minutes. The reaction was developed using MACH 1 universal HRP polymer detection system and visualized with 3’3-diamino-benzidine substrate (DAB). 100 μg Connectez-vous pour afficher 5 to 7 Days
$583.50
Détails
Humain Souris Inconjugué WB Western Blot analysis of UBASH3B expression in transfected 293T cell line by UBASH3B MaxPab polyclonal antibody.<br><br>Lane 1: UBASH3B transfected lysate(72.70 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μL Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué IF/ICC, IHC, WB Western blot analysis of extracts of various cell lines, using UBASH3B antibody (ABIN5974296) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded rat spleen using UBASH3B antibody (ABIN5974296) at dilution of 1/100 (40x lens). 100 μL Connectez-vous pour afficher 11 to 16 Days
$426.40
Détails

Plus d’anticorps contre Cbl-Interacting Protein Sts-1 partenaires d’interaction

Human Cbl-Interacting Protein Sts-1 (STS1) interaction partners

  1. Data suggest that Sts1 (suppressor of T-cell receptor signaling-1) negatively regulates TCR (T-cell receptor) signaling in activated T-lymphocytes via dephosphorylation of ZAP70 (Montrer ZAP70 Anticorps).

  2. The results show that the interaction between STS-1 and ShcA (Montrer SHC1 Anticorps) is regulated in response to EGF receptor (Montrer EGFR Anticorps) activation.

  3. The study reveals a role of CBL (Montrer CBL Anticorps) in restricting myeloid proliferation of human AML1 (Montrer RUNX1 Anticorps)-ETOinduced leukemia, and identifies UBASH3B as a potential target for pharmaceutical intervention.

  4. targeting Aurora B (Montrer AURKB Anticorps) to microtubules by UBASH3B is necessary for the timing and fidelity of chromosome segregation in human cells

  5. These results show that TULA-2 is a target of miR (Montrer MLXIP Anticorps)-148a-3p

  6. This recovery involves the phosphorylation of p70 (Montrer ANXA6 Anticorps) independent of mTOR (Montrer FRAP1 Anticorps).

  7. results demonstrate the importance of STS-1 in regulating IFN-alpha-induced autophagy in B cells

  8. UBASH3B is a functional target of anti-invasive microRNA200a that is down-regulated in triple negative breast cancer. Importantly, the oncogenic potential of UBASH3B is dependent on its tyrosine phosphatase activity.

  9. Ablation of TULA-2 resulted in hyperphosphorylation of Syk (Montrer SYK Anticorps) and its downstream effector phospholipase C (Montrer PLC Anticorps)-gamma2 as well as enhanced GPVI (Montrer GP6 Anticorps)-mediated platelet functional responses.

  10. Sts-1 and Sts-2 (Montrer UBASH3A Anticorps) bind to Cbl (Montrer CBL Anticorps) and inhibit endocytosis of receptor tyrosine kinases

Mouse (Murine) Cbl-Interacting Protein Sts-1 (STS1) interaction partners

  1. Data suggest that Sts1 (suppressor of T-cell receptor signaling-1) negatively regulates TCR (T-cell receptor) signaling in activated T-lymphocytes via dephosphorylation of Zap70 (Montrer ZAP70 Anticorps).

  2. Sts-1 and Sts-2 (Montrer UBASH3A Anticorps) are not required for the immune control of murine herpesvirus 68 in a normal course of gammaherpesvirus infection.

  3. The absence of TULA-2 and also the relative level of TULA-2 expression modulates FcgammaRIIA-mediated platelet reactivity and heparin-induced thrombocytopenia in vivo.

  4. dephosphorylation of Tyr (Montrer TYR Anticorps)(P)(346) may be considered an important "checkpoint" in the regulation of Syk (Montrer SYK Anticorps) activation process. Putative biological functions of TULA-2-mediated dephosphorylation of Tyr (Montrer TYR Anticorps)(P)(346) may include deactivation of receptor-activated Syk (Montrer SYK Anticorps) or suppression of Syk (Montrer SYK Anticorps) activation by suboptimal stimulation.

  5. Biochemical analysis identified STS-1 and STS-2 as direct phosphatases of FLT3 and c-KIT.

  6. results demonstrate the importance of STS-1 in regulating IFN-alpha-induced autophagy in B cells.

  7. The lack of TULA-2 facilitates T-cell responses to TCR/CD3 (Montrer CD3E Anticorps) stimulation, thus exacerbating T-cell-dependent inflammation.

  8. TULA-2 negatively regulates osteoclast differentiation and function.

  9. Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase (Montrer YES1 Anticorps) Syk (Montrer SYK Anticorps) interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation.

  10. Ablation of TULA-2 resulted in hyperphosphorylation of Syk (Montrer SYK Anticorps) and its downstream effector phospholipase C (Montrer PLC Anticorps)-gamma2 as well as enhanced GPVI (Montrer GP6 Anticorps)-mediated platelet functional responses.

Cbl-Interacting Protein Sts-1 (STS1) profil antigène

Profil protéine

This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.

Gene names and symbols associated with STS1

  • ubiquitin associated and SH3 domain containing B (UBASH3B) anticorps
  • ubiquitin associated and SH3 domain containing, B (Ubash3b) anticorps
  • 2810457I06Rik anticorps
  • BB125008 anticorps
  • p70 anticorps
  • RGD1310357 anticorps
  • Sts-1 anticorps
  • STS1 anticorps
  • TULA-2 anticorps

Protein level used designations for STS1

Cbl-interacting protein Sts-1 , SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate , T-cell ubiquitin ligand 2 , cbl-interacting protein p70 , nm23-phosphorylated unknown substrate , suppressor of T-cell receptor signaling 1 , tyrosine-protein phosphatase STS1/TULA2 , ubiquitin-associated and SH3 domain-containing protein B , STS-1

GENE ID SPECIES
84959 Homo sapiens
72828 Mus musculus
315579 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-Cbl-Interacting Protein Sts-1 (STS1) Anticorps
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