anti-Cell Cycle and Apoptosis Regulator 2 (CCAR2) Anticorps

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. De plus, nous expédions CCAR2 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CCAR2 57805 Q8N163
CCAR2 219158 Q8VDP4
CCAR2 306007  
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Top anti-CCAR2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 51 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB Western blot analysis of KIAA1967 expression in A549 (A), HeLa (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IF/ICC, IHC, WB Western blot analysis of extracts of various cell lines, using CCAR2 antibody (ABIN5974285) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded human kidney using CCAR2 antibody (ABIN5974285) at dilution of 1/100 (40x lens). 100 μL Connectez-vous pour afficher 11 to 16 Days
$426.40
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from Jurkat cells, using KIAA1967 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$429.62
Détails
Humain Souris Inconjugué IF, WB Immunofluorescence of monoclonal antibody to KIAA1967 on HeLa cell (antibody concentration 10 µg/mL). KIAA1967 monoclonal antibody (M04), clone 4E6 Western Blot analysis of KIAA1967 expression in A-549. 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Humain Lapin Inconjugué IF, IP, WB Immunoprecipitation of KIAA1967 transfected lysate using anti-KIAA1967 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with KIAA1967 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of KIAA1967 expression in transfected 293T cell line by KIAA1967 MaxPab polyclonal antibody.Lane 1: KIAA1967 transfected lysate(102.9 KDa).Lane 2: Non-transfected lysate. 100 μL Connectez-vous pour afficher 11 to 12 Days
$425.71
Détails
Humain Lapin Inconjugué IF, IHC, WB Western blot analysis of extracts of various cell lines, using CCAR2 antibody. Immunohistochemistry of paraffin-embedded rat kidney using CCAR2 antibody. 120 μL Connectez-vous pour afficher 12 to 14 Days
$251.90
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, WB ABIN6274424 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. Western blot analysis of extracts from Jurkat cells, using KIAA1967 antibody. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Souris Inconjugué IF, WB Western Blot analysis of KIAA1967 expression in transfected 293T cell line by KIAA1967 MaxPab polyclonal antibody.Lane 1: KIAA1967 transfected lysate(101.53 KDa).Lane 2: Non-transfected lysate. KIAA1967 MaxPab polyclonal antibody. Western Blot analysis of KIAA1967 expression in Jurkat. 50 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Souris Inconjugué ICC, IP, WB Western blot analysis of extracts of various cells, using CCAR2 antibody. 100 μL Connectez-vous pour afficher 16 Days
$407.72
Détails

Plus d’anticorps contre CCAR2 partenaires d’interaction

Human Cell Cycle and Apoptosis Regulator 2 (CCAR2) interaction partners

  1. CCAR2/DBC1 inhibits recombination by limiting the initiation and the extent of DNA end resection, thereby acting as an antagonist of CtIP (Montrer RBBP8 Anticorps).

  2. conclude, these findings demonstrated that DBC1 was essential in tumorigenesis and proliferation. Moreover, it was identified as a potential therapeutic target for HCC (Montrer FAM126A Anticorps).

  3. Long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 (Montrer TP53 Anticorps) acetylation.

  4. Data suggest that DBC1 has a dual function in regulating beta-catenin (Montrer CTNNB1 Anticorps)-PROX1 (Montrer PROX1 Anticorps) signaling axis: as a coactivator for both beta-catenin (Montrer CTNNB1 Anticorps) and PROX1 (Montrer PROX1 Anticorps).

  5. important role for CCAR2 in maintaining cell cycle progression and promoting squamous cell carcinoma (SCC (Montrer CYP11A1 Anticorps)) tumorigenesis.

  6. Data show that the interaction between cell cycle and apoptosis regulator 2 (CCAR2) and heat shock protein 60 (Hsp60 (Montrer HSPD1 Anticorps)) increases in the presence of rotenone.

  7. Results found transcriptional levels of DBC1,a negative regulator of HDAC3 (Montrer HDAC3 Anticorps) significantly reduced in type 2 diabetes mellitus patients.

  8. DBC1 protein could be a prognostic marker of shorter recurrence-free survival in hepatocellular carcinoma patients after hepatectomy and human hepatocarcinogenesis was a multistep process accompanied by a stepwise increase in high DBC1 expression from low-grade dysplastic nodules, through high-grade dysplastic nodules, to hepatocellular carcinoma.

  9. Results suggest that DBC1 is integral to the maintenance of the circadian molecular clock.

  10. loss of DBC1 expression plays a role in tumorigenesis and tumor progression in gallbladder carcinoma.

Mouse (Murine) Cell Cycle and Apoptosis Regulator 2 (CCAR2) interaction partners

  1. Dbc1 ablation increases Scd1 (Montrer SCD Anticorps) levels, causes obesity and insulin (Montrer INS Anticorps) resistance.

  2. phosphorylation of DBC1 at its C terminus by IKKalpha (Montrer CHUK Anticorps) facilitates its interaction with RelB (Montrer RELB Anticorps) and IKKalpha (Montrer CHUK Anticorps), indicating that DBC1-mediated suppression of alternative NF-kappaB (Montrer NFKB1 Anticorps) is regulated by IKKalpha (Montrer CHUK Anticorps).

  3. induced the expression of nuclear factor kappa B (NF-kappaB (Montrer NFKB1 Anticorps))-regulated inflammatory cytokines in fully differentiated 3T3-L1 adipocytes, possibly through the inhibition of Sirt1 (Montrer SIRT1 Anticorps) activity

  4. We propose that DBC1 is part of the molecular machinery that regulates fat storage capacity in adipocytes and participates in the "turn-off" switch that limits adipocyte fat accumulation.

  5. DBC1 as a novel regulator of gluconeogenesis.

  6. HDAC3 is negatively regulated by the nuclear protein DBC1

  7. New role for DBC1 as an in vivo regulator of SIRT1 (Montrer SIRT1 Anticorps) activity and liver steatosis, in which interaction with SIRT1 (Montrer SIRT1 Anticorps) may serve as a new target for therapies aimed at nonalcoholic liver steatosis.

CCAR2 profil antigène

Profil protéine

Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.

Gene names and symbols associated with CCAR2

  • cell cycle and apoptosis regulator 2 (CCAR2) anticorps
  • cell cycle activator and apoptosis regulator 2 (Ccar2) anticorps
  • cell cycle and apoptosis regulator 2 (Ccar2) anticorps
  • 2610301G19Rik anticorps
  • DBC-1 anticorps
  • DBC1 anticorps
  • Kiaa1967 anticorps
  • mKIAA1967 anticorps
  • NET35 anticorps
  • p30 DBC anticorps
  • p30DBC anticorps
  • RGD1309922 anticorps

Protein level used designations for CCAR2

DBIRD complex subunit KIAA1967 , deleted in breast cancer 1 , p30 DBC protein , DBIRD complex subunit KIAA1967 homolog , cell cycle and apoptosis regulator protein 2

GENE ID SPECIES
57805 Homo sapiens
219158 Mus musculus
306007 Rattus norvegicus
486122 Canis lupus familiaris
100155718 Sus scrofa
100730691 Cavia porcellus
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