anti-Cell Death-Inducing DFFA-Like Effector A (CIDEA) Anticorps

CIDEA encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. De plus, nous expédions CIDEA Protéines (5) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CIDEA 1149 O60543
CIDEA 12683 O70302
CIDEA 291541  
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Top anti-CIDEA Anticorps sur anticorps-enligne.fr

Showing 10 out of 99 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ELISA, ICC, IF, IHC, IHC (p), WB Western Blot: CIDEA Antibody [NBP1-76950] - Mouse heart tissue lysate with CIDE-A antibody at 1:500 dilution. Immunohistochemistry-Paraffin: CIDEA Antibody [NBP1-76950] - Mouse heart tissue with CIDE-A antibody at 5 ug/ml. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$485.88
Détails
Humain Lapin Inconjugué WB CIDEA Antibody (C-term) (ABIN657978) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the CIDEA antibody detected the CIDEA protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Souris Inconjugué IP, ELISA, WB Immunoprecipitation of CIDEA transfected lysate using anti-CIDEA monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with CIDEA MaxPab rabbit polyclonal antibody. Western Blot analysis of CIDEA expression in transfected 293T cell line by CIDEA monoclonal antibody (M01), clone 4B9.Lane 1: CIDEA transfected lysate(28.3 KDa).Lane 2: Non-transfected lysate. 100 μg Connectez-vous pour afficher 11 to 12 Days
$354.20
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Human Testis (formalin-fixed, paraffin-embedded) stained with CIDEA antibody ABIN214587 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-CIDE A antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis of CIDEA using COS7 whole cell lysates ABIN6278967 at 1/100 staining Human spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Souris Lapin Inconjugué IHC, WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Souris Lapin Inconjugué ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Connectez-vous pour afficher 13 to 16 Days
$396.00
Détails
Humain Lapin Inconjugué IF, WB Immunofluorescence analysis of A549 cell using CIDEA antibody. Blue: DAPI for nuclear staining. Immunofluorescence analysis of A549 cell using CIDEA antibody. 100 μL Connectez-vous pour afficher 16 Days
$334.77
Détails
Humain Lapin Inconjugué IHC (p), WB 50 μg Connectez-vous pour afficher 12 to 14 Days
$685.40
Détails
Humain Lapin Inconjugué ELISA, WB   100 μL Connectez-vous pour afficher 16 Days
$298.18
Détails

anti-CIDEA Anticorps mieux référencés

  1. Human Monoclonal CIDEA Primary Antibody pour IP, ELISA - ABIN514417 : Puri, Ranjit, Konda, Nicoloro, Straubhaar, Chawla, Chouinard, Lin, Burkart, Corvera, Perugini, Czech: Cidea is associated with lipid droplets and insulin sensitivity in humans. dans Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal CIDEA Primary Antibody pour ELISA, ICC - ABIN4298761 : Rohm, Schäfer, Laurent, Üstünel, Niopek, Algire, Hautzinger, Sijmonsma, Zota, Medrikova, Pellegata, Ryden, Kulyte, Dahlman, Arner, Petrovic, Cannon, Amri, Kemp, Steinberg, Janovska, Kopecky, Wolfrum et al.: An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice. ... dans Nature medicine 2016 (PubMed)

Plus d’anticorps contre CIDEA partenaires d’interaction

Human Cell Death-Inducing DFFA-Like Effector A (CIDEA) interaction partners

  1. Cidea, unexpectedly, functions molecularly as an indirect inhibitor of thermogenesis via inhibition of UCP1 (Montrer UCP1 Anticorps) activity.

  2. These data establish a functional role for Cidea and suggest that, in humans, the association between Cidea levels in white fat and metabolic health is not only correlative but also causative.

  3. Since Cide-A protein plays a role in the development of metabolic diseases such as obesity, metabolic syndrome, type 2 diabetes and their vascular complications, CIDE -A gene and protein are potential therapeutic targets for these diseases.

  4. The lowest mean relative of the gene expression for CIDE-A was observed in the group of obese patients with aortic aneurysm and lipid disorders

  5. the association of tag-single nucleotide polymorphisms and haplotype structures of the CIDEA gene with obesity in a Han Chinese population, was investigated.

  6. CIDE proteins expression correlate with tumor and survival characteristics in patients with renal cell carcinoma (Montrer MOK Anticorps).

  7. Insulin (Montrer INS Anticorps) regulates CIDEA and CIDEC (Montrer CIDEC Anticorps) expression via PI3K (Montrer PIK3CA Anticorps), and it regulates expression of each protein via Akt1 (Montrer AKT1 Anticorps)/2-and JNK2 (Montrer MAPK9 Anticorps)-dependent pathways, respectively, in human adipocytes.

  8. The proportion of subjects with CIDEA) gene V115F (G/T) polymorphism with phenotypes of metabolic syndrome in a Chinese population was significantly higher based on genotype, in the order: GG

  9. CIDEA binds to liver X receptors and regulates their activity in vitro.

  10. These data indicate that the carboxy-terminal domain of Cidea directs lipid droplet targeting, lipid droplet clustering, and triglyceride accumulation, whereas the amino terminal domain is required for Cidea-mediated development of enlarged lipid droplets

Mouse (Murine) Cell Death-Inducing DFFA-Like Effector A (CIDEA) interaction partners

  1. results suggest that FSP27beta negatively regulates CideA-promoted enlargement of lipid droplet size in brown adipocytes.

  2. The authors show demonstrate an essential role of an amphipathic helix in CIDEA, which facilitates embedding in the lipid droplet phospholipid monolayer and binds phosphatidic acid (PA).

  3. Data (including data from studies in knockout mice) suggest Cideb (Montrer CIDEB Anticorps) promotes lipid storage as droplets in hepatocytes under normal diet conditions; Cidea/Cidec (Montrer CIDEC Anticorps) promote fusion of lipid droplets leading to liver steatosis in fasting (16h) and obese mice.

  4. Cidea is highly associated with adiposity and insulin (Montrer INS Anticorps) resistance, whereas Cidec (Montrer CIDEC Anticorps) is related to insulin (Montrer INS Anticorps) sensitivity

  5. data reveal an important role of Cidea in controlling lipid droplet fusion, lipid storage in brown and white adipose tissue, and the development of obesity

  6. maternal diet modulates the age-associated changes in Cidea expression leading to the development of fatty liver

  7. Cidea is a crucial regulator of sebaceous gland lipid storage and sebum lipid secretion in mice.

  8. acts as transcriptional coactivator of C/EBPbeta (Montrer CEBPB Anticorps) in mammary glands to control lipid secretion

  9. Cidea is a critical regulator of free fatty acid-induced apoptosis as a novel downstream target for Foxo1 (Montrer FOXO1 Anticorps) in pancreatic beta-cells

  10. These data indicate that the carboxy-terminal domain of Cidea directs lipid droplet targeting, lipid droplet clustering, and triglyceride accumulation, whereas the amino terminal domain is required for Cidea-mediated development of enlarged lipid droplets

Cow (Bovine) Cell Death-Inducing DFFA-Like Effector A (CIDEA) interaction partners

  1. These results suggest that CIDE-A and UCP1 (Montrer UCP1 Anticorps) are regulated by insulin (Montrer INS Anticorps) and/or fatty acids in mammary epithelial cells and lactating mammary glands, and thereby play an important role in lipid and energy metabolism.

CIDEA profil antigène

Profil protéine

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

Gene names and symbols associated with CIDEA

  • cell death-inducing DFFA-like effector a (CIDEA) anticorps
  • cell death-inducing DNA fragmentation factor, alpha subunit-like effector A (Cidea) anticorps
  • cell death-inducing DFFA-like effector a (Cidea) anticorps
  • cell death-inducing DFFA-like effector a (cidea) anticorps
  • cell death-inducing DFFA-like effector a L homeolog (cidea.L) anticorps
  • AW212747 anticorps
  • cide-a anticorps
  • CIDEA anticorps
  • MGC89985 anticorps

Protein level used designations for CIDEA

cell death activator CIDE-A , cell death-inducing DFFA-like effector A , cell death-inducing DFFA-like effector a , cell death-inducing DNA fragmentation factor, alpha subunit-like effector A

GENE ID SPECIES
1149 Homo sapiens
12683 Mus musculus
468605 Pan troglodytes
490559 Canis lupus familiaris
527051 Bos taurus
768659 Gallus gallus
291541 Rattus norvegicus
703318 Macaca mulatta
493350 Xenopus (Silurana) tropicalis
495322 Xenopus laevis
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